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CCR6+ Th cells in the cerebrospinal fluid of persons with multiple sclerosis are dominated by pathogenic non-classic Th1 cells and GM-CSF-only-secreting Th cells.

Restorick SM, Durant L, Kalra S, Hassan-Smith G, Rathbone E, Douglas MR, Curnow SJ.

Brain Behav Immun. 2017 Mar 20. pii: S0889-1591(17)30098-3. doi: 10.1016/j.bbi.2017.03.008. [Epub ahead of print]


Meta-analysis of individual-patient data from EVAR-1, DREAM, OVER and ACE trials comparing outcomes of endovascular or open repair for abdominal aortic aneurysm over 5 years.

Powell JT, Sweeting MJ, Ulug P, Blankensteijn JD, Lederle FA, Becquemin JP, Greenhalgh RM; EVAR-1, DREAM, OVER and ACE Trialists..

Br J Surg. 2017 Feb;104(3):166-178. doi: 10.1002/bjs.10430. Review.


Integrative review of factors related to the nursing diagnosis nausea during antineoplastic chemotherapy.

Moysés AM, Durant LC, Almeida AM, Gozzo TO.

Rev Lat Am Enfermagem. 2016 Oct 10;24:e2812. doi: 10.1590/1518-8345.1176.2812. English, Portuguese, Spanish.


Age-related alterations in blood and colonic dendritic cell properties.

Vora R, Bernardo D, Durant L, Reddi D, Hart AL, Fell JM, Al-Hassi HO, Knight SC.

Oncotarget. 2016 Mar 15;7(11):11913-22. doi: 10.18632/oncotarget.7799.


Chemokine (C-C Motif) Receptor 2 Mediates Dendritic Cell Recruitment to the Human Colon but Is Not Responsible for Differences Observed in Dendritic Cell Subsets, Phenotype, and Function Between the Proximal and Distal Colon.

Bernardo D, Durant L, Mann ER, Bassity E, Montalvillo E, Man R, Vora R, Reddi D, Bayiroglu F, Fernández-Salazar L, English NR, Peake ST, Landy J, Lee GH, Malietzis G, Siaw YH, Murugananthan AU, Hendy P, Sánchez-Recio E, Phillips RK, Garrote JA, Scott P, Parkhill J, Paulsen M, Hart AL, Al-Hassi HO, Arranz E, Walker AW, Carding SR, Knight SC.

Cell Mol Gastroenterol Hepatol. 2015 Sep 3;2(1):22-39.e5. eCollection 2016 Jan.


T cell responses are elicited against Respiratory Syncytial Virus in the absence of signalling through TLRs, RLRs and IL-1R/IL-18R.

Goritzka M, Pereira C, Makris S, Durant LR, Johansson C.

Sci Rep. 2015 Dec 21;5:18533. doi: 10.1038/srep18533.


Alveolar macrophage-derived type I interferons orchestrate innate immunity to RSV through recruitment of antiviral monocytes.

Goritzka M, Makris S, Kausar F, Durant LR, Pereira C, Kumagai Y, Culley FJ, Mack M, Akira S, Johansson C.

J Exp Med. 2015 May 4;212(5):699-714. doi: 10.1084/jem.20140825. Epub 2015 Apr 20.


High sensitivity and specificity of elevated cerebrospinal fluid kappa free light chains in suspected multiple sclerosis.

Hassan-Smith G, Durant L, Tsentemeidou A, Assi LK, Faint JM, Kalra S, Douglas MR, Curnow SJ.

J Neuroimmunol. 2014 Nov 15;276(1-2):175-9. doi: 10.1016/j.jneuroim.2014.08.003. Epub 2014 Aug 8.


DNGR-1 is dispensable for CD8+ T-cell priming during respiratory syncytial virus infection.

Durant LR, Pereira C, Boakye A, Makris S, Kausar F, Goritzka M, Johansson C.

Eur J Immunol. 2014 Aug;44(8):2340-8. doi: 10.1002/eji.201444454. Epub 2014 May 30.


The VACS index accurately predicts mortality and treatment response among multi-drug resistant HIV infected patients participating in the options in management with antiretrovirals (OPTIMA) study.

Brown ST, Tate JP, Kyriakides TC, Kirkwood KA, Holodniy M, Goulet JL, Angus BJ, Cameron DW, Justice AC; OPTIMA Team..

PLoS One. 2014 Mar 25;9(3):e92606. doi: 10.1371/journal.pone.0092606. eCollection 2014.


Alpha/beta interferon receptor signaling amplifies early proinflammatory cytokine production in the lung during respiratory syncytial virus infection.

Goritzka M, Durant LR, Pereira C, Salek-Ardakani S, Openshaw PJ, Johansson C.

J Virol. 2014 Jun;88(11):6128-36. doi: 10.1128/JVI.00333-14. Epub 2014 Mar 19.


Regulatory T cells prevent Th2 immune responses and pulmonary eosinophilia during respiratory syncytial virus infection in mice.

Durant LR, Makris S, Voorburg CM, Loebbermann J, Johansson C, Openshaw PJ.

J Virol. 2013 Oct;87(20):10946-54. doi: 10.1128/JVI.01295-13. Epub 2013 Aug 7.


Novel HldE-K inhibitors leading to attenuated Gram negative bacterial virulence.

Desroy N, Denis A, Oliveira C, Atamanyuk D, Briet S, Faivre F, LeFralliec G, Bonvin Y, Oxoby M, Escaich S, Floquet S, Drocourt E, Vongsouthi V, Durant L, Moreau F, Verhey TB, Lee TW, Junop MS, Gerusz V.

J Med Chem. 2013 Feb 28;56(4):1418-30. doi: 10.1021/jm301499r. Epub 2013 Feb 14.


Defective immunoregulation in RSV vaccine-augmented viral lung disease restored by selective chemoattraction of regulatory T cells.

Loebbermann J, Durant L, Thornton H, Johansson C, Openshaw PJ.

Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):2987-92. doi: 10.1073/pnas.1217580110. Epub 2013 Feb 4.


Long-term comparison of endovascular and open repair of abdominal aortic aneurysm.

Lederle FA, Freischlag JA, Kyriakides TC, Matsumura JS, Padberg FT Jr, Kohler TR, Kougias P, Jean-Claude JM, Cikrit DF, Swanson KM; OVER Veterans Affairs Cooperative Study Group..

N Engl J Med. 2012 Nov 22;367(21):1988-97. doi: 10.1056/NEJMoa1207481.


From triclosan toward the clinic: discovery of nonbiocidal, potent FabI inhibitors for the treatment of resistant bacteria.

Gerusz V, Denis A, Faivre F, Bonvin Y, Oxoby M, Briet S, LeFralliec G, Oliveira C, Desroy N, Raymond C, Peltier L, Moreau F, Escaich S, Vongsouthi V, Floquet S, Drocourt E, Walton A, Prouvensier L, Saccomani M, Durant L, Genevard JM, Sam-Sambo V, Soulama-Mouze C.

J Med Chem. 2012 Nov 26;55(22):9914-28. doi: 10.1021/jm301113w. Epub 2012 Oct 23.


Cost-effectiveness of open versus endovascular repair of abdominal aortic aneurysm in the OVER trial.

Stroupe KT, Lederle FA, Matsumura JS, Kyriakides TC, Jonk YC, Ge L, Freischlag JA; Open Versus Endovascular Repair (OVER) Veterans Affairs Cooperative Study Group..

J Vasc Surg. 2012 Oct;56(4):901-9.e2. doi: 10.1016/j.jvs.2012.01.086. Epub 2012 May 27.


IL-10 regulates viral lung immunopathology during acute respiratory syncytial virus infection in mice.

Loebbermann J, Schnoeller C, Thornton H, Durant L, Sweeney NP, Schuijs M, O'Garra A, Johansson C, Openshaw PJ.

PLoS One. 2012;7(2):e32371. doi: 10.1371/journal.pone.0032371. Epub 2012 Feb 29.


Regulatory T cells expressing granzyme B play a critical role in controlling lung inflammation during acute viral infection.

Loebbermann J, Thornton H, Durant L, Sparwasser T, Webster KE, Sprent J, Culley FJ, Johansson C, Openshaw PJ.

Mucosal Immunol. 2012 Mar;5(2):161-72. doi: 10.1038/mi.2011.62. Epub 2012 Jan 11.


The MUT056399 inhibitor of FabI is a new antistaphylococcal compound.

Escaich S, Prouvensier L, Saccomani M, Durant L, Oxoby M, Gerusz V, Moreau F, Vongsouthi V, Maher K, Morrissey I, Soulama-Mouze C.

Antimicrob Agents Chemother. 2011 Oct;55(10):4692-7. doi: 10.1128/AAC.01248-10. Epub 2011 Aug 8.

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