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Items: 1 to 20 of 218


A mutation in the Tubb4a gene leads to microtubule accumulation with hypomyelination and demyelination.

Duncan ID, Bugiani M, Radcliff AB, Moran JJ, Lopez-Anido C, Duong P, August BK, Wolf NI, van der Knaap MS, Svaren J.

Ann Neurol. 2017 May;81(5):690-702. doi: 10.1002/ana.24930. Epub 2017 May 9.


Modeling the Chronic Loss of Optic Nerve Axons and the Effects on the Retinal Nerve Fiber Layer Structure in Primary Disorder of Myelin.

Teixeira LB, Hoeve JN, Mayer JA, Dubielzig RR, Smith CM, Radcliff AB, Duncan ID.

Invest Ophthalmol Vis Sci. 2016 Sep 1;57(11):4859-4868. doi: 10.1167/iovs.16-19871.


Myelin repair by transplantation of myelin-forming cells in globoid cell leukodystrophy.

Kondo Y, Duncan ID.

J Neurosci Res. 2016 Nov;94(11):1195-202. doi: 10.1002/jnr.23909. Epub 2016 Aug 25. Review.


Inherited and acquired disorders of myelin: The underlying myelin pathology.

Duncan ID, Radcliff AB.

Exp Neurol. 2016 Sep;283(Pt B):452-75. doi: 10.1016/j.expneurol.2016.04.002. Epub 2016 Apr 9. Review.


Myelin and oligodendrocyte development in the canine spinal cord.

Mayer JA, Figari C, Radcliff AB, Mckee C, Duncan ID.

J Comp Neurol. 2016 Apr 1;524(5):930-9. doi: 10.1002/cne.23882. Epub 2015 Sep 4.


Modeling the natural history of Pelizaeus-Merzbacher disease.

Mayer JA, Griffiths IR, Goldman JE, Smith CM, Cooksey E, Radcliff AB, Duncan ID.

Neurobiol Dis. 2015 Mar;75:115-30. doi: 10.1016/j.nbd.2014.12.023. Epub 2015 Jan 3.


A mutation in the canine gene encoding folliculin-interacting protein 2 (FNIP2) associated with a unique disruption in spinal cord myelination.

Pemberton TJ, Choi S, Mayer JA, Li FY, Gokey N, Svaren J, Safra N, Bannasch DL, Sullivan K, Breuhaus B, Patel PI, Duncan ID.

Glia. 2014 Jan;62(1):39-51. doi: 10.1002/glia.22582.


Modality-based organization of ascending somatosensory axons in the direct dorsal column pathway.

Niu J, Ding L, Li JJ, Kim H, Liu J, Li H, Moberly A, Badea TC, Duncan ID, Son YJ, Scherer SS, Luo W.

J Neurosci. 2013 Nov 6;33(45):17691-709. doi: 10.1523/JNEUROSCI.3429-13.2013.


q-Space diffusion MRI (QSI) of the disease progression in the spinal cords of the Long Evans shaker: diffusion time and apparent anisotropy.

Anaby D, Duncan ID, Smith CM, Cohen Y.

NMR Biomed. 2013 Dec;26(12):1879-86. doi: 10.1002/nbm.3043. Epub 2013 Oct 9.


White matter maturation in the brains of Long Evans shaker myelin mutant rats by ex-vivo QSI and DTI.

Anaby D, Duncan ID, Smith CM, Cohen Y.

Magn Reson Imaging. 2013 Sep;31(7):1097-104. doi: 10.1016/j.mri.2013.03.020. Epub 2013 May 6.


Autophagy promotes oligodendrocyte survival and function following dysmyelination in a long-lived myelin mutant.

Smith CM, Mayer JA, Duncan ID.

J Neurosci. 2013 May 1;33(18):8088-100. doi: 10.1523/JNEUROSCI.0233-13.2013.


Spontaneous optic nerve compression in the osteopetrotic (op/op) mouse: a novel model of myelination failure.

Kondo Y, Ramaker JM, Radcliff AB, Baldassari S, Mayer JA, Ver Hoeve JN, Zhang CL, Chiu SY, Colello RJ, Duncan ID.

J Neurosci. 2013 Feb 20;33(8):3514-25. doi: 10.1523/JNEUROSCI.4849-12.2013.


Myelin loss does not lead to axonal degeneration in a long-lived model of chronic demyelination.

Smith CM, Cooksey E, Duncan ID.

J Neurosci. 2013 Feb 6;33(6):2718-27. doi: 10.1523/JNEUROSCI.4627-12.2013.


CD44 is required for the migration of transplanted oligodendrocyte progenitor cells to focal inflammatory demyelinating lesions in the spinal cord.

Piao JH, Wang Y, Duncan ID.

Glia. 2013 Mar;61(3):361-7. doi: 10.1002/glia.22438. Epub 2012 Dec 22.


Cervical spinal demyelination with ethidium bromide impairs respiratory (phrenic) activity and forelimb motor behavior in rats.

Nichols NL, Punzo AM, Duncan ID, Mitchell GS, Johnson RA.

Neuroscience. 2013 Jan 15;229:77-87. doi: 10.1016/j.neuroscience.2012.10.066. Epub 2012 Nov 14.


Quantitative MR imaging of two-pool magnetization transfer model parameters in myelin mutant shaking pup.

Samsonov A, Alexander AL, Mossahebi P, Wu YC, Duncan ID, Field AS.

Neuroimage. 2012 Sep;62(3):1390-8. doi: 10.1016/j.neuroimage.2012.05.077. Epub 2012 Jun 1.


Hyccin, the molecule mutated in the leukodystrophy hypomyelination and congenital cataract (HCC), is a neuronal protein.

Gazzerro E, Baldassari S, Giacomini C, Musante V, Fruscione F, La Padula V, Biancheri R, Scarfì S, Prada V, Sotgia F, Duncan ID, Zara F, Werner HB, Lisanti MP, Nobbio L, Corradi A, Minetti C.

PLoS One. 2012;7(3):e32180. doi: 10.1371/journal.pone.0032180. Epub 2012 Mar 26.


The myelin mutants as models to study myelin repair in the leukodystrophies.

Duncan ID, Kondo Y, Zhang SC.

Neurotherapeutics. 2011 Oct;8(4):607-24. doi: 10.1007/s13311-011-0080-y. Review.


Migration and remyelination by oligodendrocyte progenitor cells transplanted adjacent to focal areas of spinal cord inflammation.

Wang Y, Piao JH, Larsen EC, Kondo Y, Duncan ID.

J Neurosci Res. 2011 Nov;89(11):1737-46. doi: 10.1002/jnr.22716. Epub 2011 Jul 25.


Characterization of a PLP-overexpressing transgenic rat, a model for the connatal form of Pelizaeus-Merzbacher disease.

Mayer JA, Larsen EC, Kondo Y, Duncan ID.

Neurobiol Dis. 2011 Nov;44(2):231-8. doi: 10.1016/j.nbd.2011.07.007. Epub 2011 Jul 18. Erratum in: Neurobiol Dis. 2012 Dec;48(3):507.


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