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Items: 14

1.

p38 inhibition and not MK2 inhibition enhances the secretion of chemokines from TNF-α activated rheumatoid arthritis fibroblast-like synoviocytes.

Dulos J, Wijnands FP, van den Hurk-van Alebeek JA, van Vugt MJ, Rullmann JA, Schot JJ, de Groot MW, Wagenaars JL, van Ravestein-van Os R, Smets RL, Vink PM, Hofstra CL, Nelissen RL, van Eenennaam H.

Clin Exp Rheumatol. 2013 Jul-Aug;31(4):515-25. Epub 2013 Apr 3.

PMID:
23558031
2.

Exposure to Candida albicans polarizes a T-cell driven arthritis model towards Th17 responses, resulting in a more destructive arthritis.

Marijnissen RJ, Koenders MI, van de Veerdonk FL, Dulos J, Netea MG, Boots AM, Joosten LA, van den Berg WB.

PLoS One. 2012;7(6):e38889. doi: 10.1371/journal.pone.0038889. Epub 2012 Jun 12.

3.

PD-1 blockade augments Th1 and Th17 and suppresses Th2 responses in peripheral blood from patients with prostate and advanced melanoma cancer.

Dulos J, Carven GJ, van Boxtel SJ, Evers S, Driessen-Engels LJ, Hobo W, Gorecka MA, de Haan AF, Mulders P, Punt CJ, Jacobs JF, Schalken JA, Oosterwijk E, van Eenennaam H, Boots AM.

J Immunother. 2012 Feb-Mar;35(2):169-78. doi: 10.1097/CJI.0b013e318247a4e7.

PMID:
22306905
4.

T cell lessons from the rheumatoid arthritis synovium SCID mouse model: CD3-rich synovium lacks response to CTLA-4Ig but is successfully treated by interleukin-17 neutralization.

Koenders MI, Marijnissen RJ, Joosten LA, Abdollahi-Roodsaz S, Di Padova FE, van de Loo FA, Dulos J, van den Berg WB, Boots AM.

Arthritis Rheum. 2012 Jun;64(6):1762-70. doi: 10.1002/art.34352. Epub 2011 Dec 27.

5.

Discovery of selective and orally available spiro-3-piperidyl ATP-competitive MK2 inhibitors.

Kaptein A, Oubrie A, de Zwart E, Hoogenboom N, de Wit J, van de Kar B, van Hoek M, Vogel G, de Kimpe V, Schultz-Fademrecht C, Borsboom J, van Zeeland M, Versteegh J, Kazemier B, de Roos J, Wijnands F, Dulos J, Jaeger M, Leandro-Garcia P, Barf T.

Bioorg Med Chem Lett. 2011 Jun 15;21(12):3823-7. doi: 10.1016/j.bmcl.2011.04.016. Epub 2011 Apr 16.

PMID:
21565498
6.

Suppression of the inflammatory response in experimental arthritis is mediated via estrogen receptor alpha but not estrogen receptor beta.

Dulos J, Vijn P, van Doorn C, Hofstra CL, Veening-Griffioen D, de Graaf J, Dijcks FA, Boots AM.

Arthritis Res Ther. 2010;12(3):R101. doi: 10.1186/ar3032. Epub 2010 May 24.

7.

Therapeutic antibody targeting of CD97 in experimental arthritis: the role of antigen expression, shedding, and internalization on the pharmacokinetics of anti-CD97 monoclonal antibody 1B2.

de Groot DM, Vogel G, Dulos J, Teeuwen L, Stebbins K, Hamann J, Owens BM, van Eenennaam H, Bos E, Boots AM.

J Immunol. 2009 Sep 15;183(6):4127-34. doi: 10.4049/jimmunol.0901253. Epub 2009 Aug 28.

8.

A potent and selective p38 inhibitor protects against bone damage in murine collagen-induced arthritis: a comparison with neutralization of mouse TNFalpha.

Mihara K, Almansa C, Smeets RL, Loomans EE, Dulos J, Vink PM, Rooseboom M, Kreutzer H, Cavalcanti F, Boots AM, Nelissen RL.

Br J Pharmacol. 2008 May;154(1):153-64. doi: 10.1038/bjp.2008.53. Epub 2008 Feb 25.

9.
11.

CYP7B expression and activity in fibroblast-like synoviocytes from patients with rheumatoid arthritis: regulation by proinflammatory cytokines.

Dulos J, van der Vleuten MA, Kavelaars A, Heijnen CJ, Boots AM.

Arthritis Rheum. 2005 Mar;52(3):770-8.

12.
13.

A study on cell lineage, especially the germ cell line, in embryos of the teleost fish,Barbus conchonius.

Gevers P, Dulos J, van den Boogaart JG, Timmermans LP.

Roux Arch Dev Biol. 1992 Sep;201(5):275-283. doi: 10.1007/BF00592108.

PMID:
28305831
14.

Origin of primordial germ cells, as characterized by the presence of nuage, in embryos of the teleost fish Barbus conchonius.

Gevers P, Dulos J, Schipper H, Timmermans LP.

Eur J Morphol. 1992;30(3):195-204.

PMID:
1295556

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