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Items: 1 to 20 of 91

1.

Novel Therapeutics Identification for Fibrosis in Renal Allograft Using Integrative Informatics Approach.

Li L, Greene I, Readhead B, Menon MC, Kidd BA, Uzilov AV, Wei C, Philippe N, Schroppel B, He JC, Chen R, Dudley JT, Murphy B.

Sci Rep. 2017 Jan 4;7:39487. doi: 10.1038/srep39487.

2.

Intracoronary Imaging, Cholesterol Efflux, and Transcriptomes after Intensive Statin Treatment: The YELLOW II study.

Kini AS, Vengrenyuk Y, Shameer K, Maehara A, Purushothaman M, Yoshimura T, Matsumura M, Aquino M, Haider N, Johnson KW, Readhead B, Kidd BA, Feig JE, Krishnan P, Sweeny J, Mahajan M, Moreno P, Mehran R, Kovacic JC, Baber U, Dudley JT, Narula J, Sharma S.

J Am Coll Cardiol. 2016 Oct 27. pii: S0735-1097(16)36776-6. doi: 10.1016/j.jacc.2016.10.029. [Epub ahead of print]

PMID:
27989886
3.

Genomic Analysis of Kidney Allograft Injury Identifies Hematopoietic Cell Kinase as a Key Driver of Renal Fibrosis.

Wei C, Li L, Menon MC, Zhang W, Fu J, Kidd B, Keung KL, Woytovich C, Greene I, Xiao W, Salem F, Yi Z, He JC, Dudley JT, Murphy B.

J Am Soc Nephrol. 2016 Dec 7. pii: ASN.2016020238. [Epub ahead of print]

PMID:
27927780
4.

PREDICTIVE MODELING OF HOSPITAL READMISSION RATES USING ELECTRONIC MEDICAL RECORD-WIDE MACHINE LEARNING: A CASE-STUDY USING MOUNT SINAI HEART FAILURE COHORT.

Shameer K, Johnson KW, Yahi A, Miotto R, Li LI, Ricks D, Jebakaran J, Kovatch P, Sengupta PP, Gelijns S, Moskovitz A, Darrow B, David DL, Kasarskis A, Tatonetti NP, Pinney S, Dudley JT.

Pac Symp Biocomput. 2016;22:276-287.

5.

EXPLORING THE REPRODUCIBILITY OF PROBABILISTIC CAUSAL MOLECULAR NETWORK MODELS.

Cohain A, Divaraniya AA, Zhu K, Scarpa JR, Kasarskis A, Zhu J, Chang R, Dudley JT, Schadt EE.

Pac Symp Biocomput. 2016;22:120-131.

6.

Machine-Learning Algorithms to Automate Morphological and Functional Assessments in 2D Echocardiography.

Narula S, Shameer K, Salem Omar AM, Dudley JT, Sengupta PP.

J Am Coll Cardiol. 2016 Nov 29;68(21):2287-2295. doi: 10.1016/j.jacc.2016.08.062.

PMID:
27884247
7.

Transcriptional Profiling of Egg Allergy and Relationship to Disease Phenotype.

Kosoy R, Agashe C, Grishin A, Leung DY, Wood RA, Sicherer SH, Jones SM, Burks AW, Davidson WF, Lindblad RW, Dawson P, Merad M, Kidd BA, Dudley JT, Sampson HA, Berin MC.

PLoS One. 2016 Oct 27;11(10):e0163831. doi: 10.1371/journal.pone.0163831.

8.

Gene expression elucidates functional impact of polygenic risk for schizophrenia.

Fromer M, Roussos P, Sieberts SK, Johnson JS, Kavanagh DH, Perumal TM, Ruderfer DM, Oh EC, Topol A, Shah HR, Klei LL, Kramer R, Pinto D, Gümüş ZH, Cicek AE, Dang KK, Browne A, Lu C, Xie L, Readhead B, Stahl EA, Xiao J, Parvizi M, Hamamsy T, Fullard JF, Wang YC, Mahajan MC, Derry JM, Dudley JT, Hemby SE, Logsdon BA, Talbot K, Raj T, Bennett DA, De Jager PL, Zhu J, Zhang B, Sullivan PF, Chess A, Purcell SM, Shinobu LA, Mangravite LM, Toyoshiba H, Gur RE, Hahn CG, Lewis DA, Haroutunian V, Peters MA, Lipska BK, Buxbaum JD, Schadt EE, Hirai K, Roeder K, Brennand KJ, Katsanis N, Domenici E, Devlin B, Sklar P.

Nat Neurosci. 2016 Nov;19(11):1442-1453. doi: 10.1038/nn.4399.

PMID:
27668389
9.

Gold Nanoparticle Reprograms Pancreatic Tumor Microenvironment and Inhibits Tumor Growth.

Saha S, Xiong X, Chakraborty PK, Shameer K, Arvizo RR, Kudgus RA, Dwivedi SK, Hossen MN, Gillies EM, Robertson JD, Dudley JT, Urrutia RA, Postier RG, Bhattacharya R, Mukherjee P.

ACS Nano. 2016 Dec 27;10(12):10636-10651. doi: 10.1021/acsnano.6b02231.

PMID:
27758098
10.

Influence of age on androgen deprivation therapy-associated Alzheimer's disease.

Nead KT, Gaskin G, Chester C, Swisher-McClure S, Dudley JT, Leeper NJ, Shah NH.

Sci Rep. 2016 Oct 18;6:35695. doi: 10.1038/srep35695.

11.

Replicating Cardiovascular Condition-Birth Month Associations.

Li L, Boland MR, Miotto R, Tatonetti NP, Dudley JT.

Sci Rep. 2016 Sep 14;6:33166. doi: 10.1038/srep33166.

12.

Deep phenotyping predicts Huntington's genotype.

Ruderfer DM, Dudley JT.

Nat Biotechnol. 2016 Aug 9;34(8):823-4. doi: 10.1038/nbt.3648. No abstract available.

PMID:
27504774
13.

Systems Genetic Analyses Highlight a TGFβ-FOXO3 Dependent Striatal Astrocyte Network Conserved across Species and Associated with Stress, Sleep, and Huntington's Disease.

Scarpa JR, Jiang P, Losic B, Readhead B, Gao VD, Dudley JT, Vitaterna MH, Turek FW, Kasarskis A.

PLoS Genet. 2016 Jul 8;12(7):e1006137. doi: 10.1371/journal.pgen.1006137.

14.

Evaluation of direct-to-consumer low-volume lab tests in healthy adults.

Kidd BA, Hoffman G, Zimmerman N, Li L, Morgan JW, Glowe PK, Botwin GJ, Parekh S, Babic N, Doust MW, Stock GB, Schadt EE, Dudley JT.

J Clin Invest. 2016 Jul 1;126(7):2773. doi: 10.1172/JCI88464. No abstract available.

15.

Comparative analyses of population-scale phenomic data in electronic medical records reveal race-specific disease networks.

Glicksberg BS, Li L, Badgeley MA, Shameer K, Kosoy R, Beckmann ND, Pho N, Hakenberg J, Ma M, Ayers KL, Hoffman GE, Dan Li S, Schadt EE, Patel CJ, Chen R, Dudley JT.

Bioinformatics. 2016 Jun 15;32(12):i101-i110. doi: 10.1093/bioinformatics/btw282.

16.

Reply to R.L. Bowen et al, M. Froehner et al, J.L. Leow et al, and C. Brady et al.

Nead KT, Gaskin G, Chester C, Swisher-McClure S, Dudley JT, Leeper NJ, Shah NH.

J Clin Oncol. 2016 Aug 10;34(23):2804-5. doi: 10.1200/JCO.2016.67.9449. No abstract available.

PMID:
27298415
17.

Important role of kallikrein 6 for the development of keratinocyte proliferative resistance to topical glucocorticoids.

Kishibe M, Baida G, Bhalla P, Lavker RM, Schlosser B, Iinuma S, Yoshida S, Dudley JT, Budunova I.

Oncotarget. 2016 Oct 25;7(43):69479-69488. doi: 10.18632/oncotarget.9926.

18.

Cognitive Machine-Learning Algorithm for Cardiac Imaging: A Pilot Study for Differentiating Constrictive Pericarditis From Restrictive Cardiomyopathy.

Sengupta PP, Huang YM, Bansal M, Ashrafi A, Fisher M, Shameer K, Gall W, Dudley JT.

Circ Cardiovasc Imaging. 2016 Jun;9(6). pii: e004330. doi: 10.1161/CIRCIMAGING.115.004330.

PMID:
27266599
19.

Development and clinical application of an integrative genomic approach to personalized cancer therapy.

Uzilov AV, Ding W, Fink MY, Antipin Y, Brohl AS, Davis C, Lau CY, Pandya C, Shah H, Kasai Y, Powell J, Micchelli M, Castellanos R, Zhang Z, Linderman M, Kinoshita Y, Zweig M, Raustad K, Cheung K, Castillo D, Wooten M, Bourzgui I, Newman LC, Deikus G, Mathew B, Zhu J, Glicksberg BS, Moe AS, Liao J, Edelmann L, Dudley JT, Maki RG, Kasarskis A, Holcombe RF, Mahajan M, Hao K, Reva B, Longtine J, Starcevic D, Sebra R, Donovan MJ, Li S, Schadt EE, Chen R.

Genome Med. 2016 Jun 1;8(1):62. doi: 10.1186/s13073-016-0313-0.

20.

Data-Driven Identification of Risk Factors of Patient Satisfaction at a Large Urban Academic Medical Center.

Li L, Lee NJ, Glicksberg BS, Radbill BD, Dudley JT.

PLoS One. 2016 May 26;11(5):e0156076. doi: 10.1371/journal.pone.0156076.

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