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Items: 1 to 20 of 146

1.

Causal Associations of Adiposity and Body Fat Distribution with Coronary Heart Disease, Stroke Subtypes and Type 2 Diabetes: A Mendelian Randomization Analysis.

Dale C, Fatemifar G, Palmer T, White J, Prieto-Merino D, Zabaneh D, Engmann JEL, Shah T, Wong A, Warren HR, McLachlan S, Trompet S, Moldovan M, Morris RW, Sofat R, Kumari M, Hyppönen E, Jefferis BJ, Gaunt TR, Ben-Shlomo Y, Zhou A, Gentry-Maharaj A, Ryan A, de Mutsert R, Noordam R, Caulfield MJ, Jukema JW, Worrall BB, Munroe PB, Menon U, Power C, Kuh D, Lawlor DA, Humphries SE, Mook-Kanamori DO, Davey Smith G, Sattar N, Kivimaki M, Price JF, Dudbridge F, Hingorani AD, Holmes MV, Casas JP; UCLEB consortium and METASTROKE consortium ..

Circulation. 2017 May 12. pii: CIRCULATIONAHA.116.026560. doi: 10.1161/CIRCULATIONAHA.116.026560. [Epub ahead of print]

PMID:
28500271
2.

Genome-wide association study meta-analysis for quantitative ultrasound parameters of bone identifies five novel loci for broadband ultrasound attenuation.

Mullin BH, Hua Zhao J, Brown SJ, Perry JRB, Luan J, Zheng HF, Langenberg C, Dudbridge F, Scott R, Wareham NJ, Spector TD, Brent Richards J, Walsh JP, Wilson SG.

Hum Mol Genet. 2017 May 4. doi: 10.1093/hmg/ddx174. [Epub ahead of print]

PMID:
28472463
3.

Genetic correlation between amyotrophic lateral sclerosis and schizophrenia.

McLaughlin RL, Schijven D, van Rheenen W, van Eijk KR, O'Brien M, Kahn RS, Ophoff RA, Goris A, Bradley DG, Al-Chalabi A, van den Berg LH, Luykx JJ, Hardiman O, Veldink JH; Project MinE GWAS Consortium.; Schizophrenia Working Group of the Psychiatric Genomics Consortium..

Nat Commun. 2017 Mar 21;8:14774. doi: 10.1038/ncomms14774.

4.

Exploration of a Polygenic Risk Score for Alcohol Consumption: A Longitudinal Analysis from the ALSPAC Cohort.

Taylor M, Simpkin AJ, Haycock PC, Dudbridge F, Zuccolo L.

PLoS One. 2016 Nov 30;11(11):e0167360. doi: 10.1371/journal.pone.0167360. eCollection 2016.

5.

Comparison of variance estimators for meta-analysis of instrumental variable estimates.

Schmidt AF, Hingorani AD, Jefferis BJ, White J, Groenwold RH, Dudbridge F; UCLEB Consortium..

Int J Epidemiol. 2016 Sep 2. pii: dyw123. [Epub ahead of print]

PMID:
27591262
6.

Marginal role for 53 common genetic variants in cardiovascular disease prediction.

Morris RW, Cooper JA, Shah T, Wong A, Drenos F, Engmann J, McLachlan S, Jefferis B, Dale C, Hardy R, Kuh D, Ben-Shlomo Y, Wannamethee SG, Whincup PH, Casas JP, Kivimaki M, Kumari M, Talmud PJ, Price JF, Dudbridge F, Hingorani AD, Humphries SE; UCLEB Consortium..

Heart. 2016 Oct 15;102(20):1640-7. doi: 10.1136/heartjnl-2016-309298. Epub 2016 Jun 30.

7.

Mendelian Randomisation study of the influence of eGFR on coronary heart disease.

Charoen P, Nitsch D, Engmann J, Shah T, White J, Zabaneh D, Jefferis B, Wannamethee G, Whincup P, Mulick Cassidy A, Gaunt T, Day I, McLachlan S, Price J, Kumari M, Kivimaki M, Brunner E, Langenberg C, Ben-Shlomo Y, Hingorani A, Whittaker J, Pablo Casas J, Dudbridge F; UCLEB Consortium..

Sci Rep. 2016 Jun 24;6:28514. doi: 10.1038/srep28514.

8.

Polygenic Epidemiology.

Dudbridge F.

Genet Epidemiol. 2016 May;40(4):268-72. doi: 10.1002/gepi.21966. Epub 2016 Apr 7. Review.

9.

Cytochrome P450 Allele CYP3A7*1C Associates with Adverse Outcomes in Chronic Lymphocytic Leukemia, Breast, and Lung Cancer.

Johnson N, De Ieso P, Migliorini G, Orr N, Broderick P, Catovsky D, Matakidou A, Eisen T, Goldsmith C, Dudbridge F, Peto J, Dos-Santos-Silva I, Ashworth A, Ross G, Houlston RS, Fletcher O.

Cancer Res. 2016 Mar 15;76(6):1485-93. doi: 10.1158/0008-5472.CAN-15-1410.

10.

Genome-wide association study using family-based cohorts identifies the WLS and CCDC170/ESR1 loci as associated with bone mineral density.

Mullin BH, Walsh JP, Zheng HF, Brown SJ, Surdulescu GL, Curtis C, Breen G, Dudbridge F, Richards JB, Spector TD, Wilson SG.

BMC Genomics. 2016 Feb 25;17:136. doi: 10.1186/s12864-016-2481-0.

11.

Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept.

Franke B, Stein JL, Ripke S, Anttila V, Hibar DP, van Hulzen KJ, Arias-Vasquez A, Smoller JW, Nichols TE, Neale MC, McIntosh AM, Lee P, McMahon FJ, Meyer-Lindenberg A, Mattheisen M, Andreassen OA, Gruber O, Sachdev PS, Roiz-Santiañez R, Saykin AJ, Ehrlich S, Mather KA, Turner JA, Schwarz E, Thalamuthu A, Yao Y, Ho YY, Martin NG, Wright MJ; Schizophrenia Working Group of the Psychiatric Genomics Consortium.; Psychosis Endophenotypes International Consortium.; Wellcome Trust Case Control Consortium 2.; Enigma Consortium., O'Donovan MC, Thompson PM, Neale BM, Medland SE, Sullivan PF.

Nat Neurosci. 2016 Mar;19(3):420-31. doi: 10.1038/nn.4228. Epub 2016 Feb 1.

12.

Schizophrenia risk from complex variation of complement component 4.

Sekar A, Bialas AR, de Rivera H, Davis A, Hammond TR, Kamitaki N, Tooley K, Presumey J, Baum M, Van Doren V, Genovese G, Rose SA, Handsaker RE; Schizophrenia Working Group of the Psychiatric Genomics Consortium., Daly MJ, Carroll MC, Stevens B, McCarroll SA.

Nature. 2016 Feb 11;530(7589):177-83. doi: 10.1038/nature16549. Epub 2016 Jan 27.

13.

Re: Is the Risk Difference Really a More Heterogeneous Measure?

Schmidt AF, Dudbridge F, Groenwold RH.

Epidemiology. 2016 May;27(3):e12. doi: 10.1097/EDE.0000000000000444. No abstract available.

PMID:
26808601
14.

Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis.

White J, Sofat R, Hemani G, Shah T, Engmann J, Dale C, Shah S, Kruger FA, Giambartolomei C, Swerdlow DI, Palmer T, McLachlan S, Langenberg C, Zabaneh D, Lovering R, Cavadino A, Jefferis B, Finan C, Wong A, Amuzu A, Ong K, Gaunt TR, Warren H, Davies TL, Drenos F, Cooper J, Ebrahim S, Lawlor DA, Talmud PJ, Humphries SE, Power C, Hypponen E, Richards M, Hardy R, Kuh D, Wareham N, Ben-Shlomo Y, Day IN, Whincup P, Morris R, Strachan MW, Price J, Kumari M, Kivimaki M, Plagnol V, Whittaker JC; International Consortium for Blood Pressure (ICBP)., Smith GD, Dudbridge F, Casas JP, Holmes MV, Hingorani AD; UCLEB (University College London-London School of Hygiene & Tropical Medicine-Edinburgh-Bristol Consortium..

Lancet Diabetes Endocrinol. 2016 Apr;4(4):327-36. doi: 10.1016/S2213-8587(15)00386-1. Epub 2016 Jan 16.

15.

Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness.

Bigdeli TB, Ripke S, Bacanu SA, Lee SH, Wray NR, Gejman PV, Rietschel M, Cichon S, St Clair D, Corvin A, Kirov G, McQuillin A, Gurling H, Rujescu D, Andreassen OA, Werge T, Blackwood DH, Pato CN, Pato MT, Malhotra AK, O'Donovan MC, Kendler KS, Fanous AH; Schizophrenia Working Group of the Psychiatric Genomics Consortium..

Am J Med Genet B Neuropsychiatr Genet. 2016 Mar;171B(2):276-89. doi: 10.1002/ajmg.b.32402. Epub 2015 Dec 11.

PMID:
26663532
16.

Combining information on multiple instrumental variables in Mendelian randomization: comparison of allele score and summarized data methods.

Burgess S, Dudbridge F, Thompson SG.

Stat Med. 2016 May 20;35(11):1880-906. doi: 10.1002/sim.6835. Epub 2015 Dec 13.

17.

A genome-wide association study of asthma symptoms in Latin American children.

Costa GN, Dudbridge F, Fiaccone RL, da Silva TM, Conceição JS, Strina A, Figueiredo CA, Magalhães WC, Rodrigues MR, Gouveia MH, Kehdy FS, Horimoto AR, Horta B, Burchard EG, Pino-Yanes M, Del Rio Navarro B, Romieu I, Hancock DB, London S, Lima-Costa MF, Pereira AC, Tarazona E, Rodrigues LC, Barreto ML.

BMC Genet. 2015 Dec 3;16:141. doi: 10.1186/s12863-015-0296-7.

18.

Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis.

Loh PR, Bhatia G, Gusev A, Finucane HK, Bulik-Sullivan BK, Pollack SJ; Schizophrenia Working Group of Psychiatric Genomics Consortium., de Candia TR, Lee SH, Wray NR, Kendler KS, O'Donovan MC, Neale BM, Patterson N, Price AL.

Nat Genet. 2015 Dec;47(12):1385-92. doi: 10.1038/ng.3431. Epub 2015 Nov 2.

19.

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores.

Vilhjálmsson BJ, Yang J, Finucane HK, Gusev A, Lindström S, Ripke S, Genovese G, Loh PR, Bhatia G, Do R, Hayeck T, Won HH; Schizophrenia Working Group of the Psychiatric Genomics Consortium, Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE) study., Kathiresan S, Pato M, Pato C, Tamimi R, Stahl E, Zaitlen N, Pasaniuc B, Belbin G, Kenny EE, Schierup MH, De Jager P, Patsopoulos NA, McCarroll S, Daly M, Purcell S, Chasman D, Neale B, Goddard M, Visscher PM, Kraft P, Patterson N, Price AL.

Am J Hum Genet. 2015 Oct 1;97(4):576-92. doi: 10.1016/j.ajhg.2015.09.001.

20.

Retrospective analysis of the quality of reports by author-suggested and non-author-suggested reviewers in journals operating on open or single-blind peer review models.

Kowalczuk MK, Dudbridge F, Nanda S, Harriman SL, Patel J, Moylan EC.

BMJ Open. 2015 Sep 29;5(9):e008707. doi: 10.1136/bmjopen-2015-008707.

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