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Items: 1 to 20 of 103

1.

Novel N,N-dialkyl cyanocinnamic acids as monocarboxylate transporter 1 and 4 inhibitors.

Jonnalagadda S, Jonnalagadda SK, Ronayne CT, Nelson GL, Solano LN, Rumbley J, Holy J, Mereddy VR, Drewes LR.

Oncotarget. 2019 Mar 22;10(24):2355-2368. doi: 10.18632/oncotarget.26760. eCollection 2019 Mar 22.

2.

Development and radiosynthesis of the first 18 F-labeled inhibitor of monocarboxylate transporters (MCTs).

Sadeghzadeh M, Moldovan RP, Fischer S, Wenzel B, Ludwig FA, Teodoro R, Deuther-Conrad W, Jonnalagadda S, Jonnalagadda SK, Gudelis E, Šačkus A, Higuchi K, Ganapathy V, Mereddy VR, Drewes LR, Brust P.

J Labelled Comp Radiopharm. 2019 Jun 30;62(8):411-424. doi: 10.1002/jlcr.3739.

PMID:
31017677
3.

The year in review: progress in brain barriers and brain fluid research in 2018.

Keep RF, Jones HC, Drewes LR.

Fluids Barriers CNS. 2019 Feb 5;16(1):4. doi: 10.1186/s12987-019-0124-y.

4.

Vascular dysfunction-The disregarded partner of Alzheimer's disease.

Sweeney MD, Montagne A, Sagare AP, Nation DA, Schneider LS, Chui HC, Harrington MG, Pa J, Law M, Wang DJJ, Jacobs RE, Doubal FN, Ramirez J, Black SE, Nedergaard M, Benveniste H, Dichgans M, Iadecola C, Love S, Bath PM, Markus HS, Salman RA, Allan SM, Quinn TJ, Kalaria RN, Werring DJ, Carare RO, Touyz RM, Williams SCR, Moskowitz MA, Katusic ZS, Lutz SE, Lazarov O, Minshall RD, Rehman J, Davis TP, Wellington CL, González HM, Yuan C, Lockhart SN, Hughes TM, Chen CLH, Sachdev P, O'Brien JT, Skoog I, Pantoni L, Gustafson DR, Biessels GJ, Wallin A, Smith EE, Mok V, Wong A, Passmore P, Barkof F, Muller M, Breteler MMB, Román GC, Hamel E, Seshadri S, Gottesman RF, van Buchem MA, Arvanitakis Z, Schneider JA, Drewes LR, Hachinski V, Finch CE, Toga AW, Wardlaw JM, Zlokovic BV.

Alzheimers Dement. 2019 Jan;15(1):158-167. doi: 10.1016/j.jalz.2018.07.222.

5.

mTOR signaling in VIP neurons regulates circadian clock synchrony and olfaction.

Liu D, Stowie A, de Zavalia N, Leise T, Pathak SS, Drewes LR, Davidson AJ, Amir S, Sonenberg N, Cao R.

Proc Natl Acad Sci U S A. 2018 Apr 3;115(14):E3296-E3304. doi: 10.1073/pnas.1721578115. Epub 2018 Mar 19.

6.

Progress in brain barriers and brain fluid research in 2017.

Keep RF, Jones HC, Drewes LR.

Fluids Barriers CNS. 2018 Feb 2;15(1):6. doi: 10.1186/s12987-018-0091-8.

7.

Neurovascular Unit: Basic and Clinical Imaging with Emphasis on Advantages of Ferumoxytol.

Netto JP, Iliff J, Stanimirovic D, Krohn KA, Hamilton B, Varallyay C, Gahramanov S, Daldrup-Link H, d'Esterre C, Zlokovic B, Sair H, Lee Y, Taheri S, Jain R, Panigrahy A, Reich DS, Drewes LR, Castillo M, Neuwelt EA.

Neurosurgery. 2018 Jun 1;82(6):770-780. doi: 10.1093/neuros/nyx357.

8.

Hibernation-based blood loss therapy increases survivability of lethal hemorrhagic shock in rats.

Perez de Lara Rodriguez CE, Drewes LR, Andrews MT.

J Comp Physiol B. 2017 Jul;187(5-6):769-778. doi: 10.1007/s00360-017-1076-7. Epub 2017 Mar 21.

PMID:
28324159
9.

Brain barriers and brain fluid research in 2016: advances, challenges and controversies.

Keep RF, Jones HC, Drewes LR.

Fluids Barriers CNS. 2017 Feb 2;14(1):4. doi: 10.1186/s12987-017-0052-7.

10.

Coumarin carboxylic acids as monocarboxylate transporter 1 inhibitors: In vitro and in vivo studies as potential anticancer agents.

Gurrapu S, Jonnalagadda SK, Alam MA, Ronayne CT, Nelson GL, Solano LN, Lueth EA, Drewes LR, Mereddy VR.

Bioorg Med Chem Lett. 2016 Jul 15;26(14):3282-3286. doi: 10.1016/j.bmcl.2016.05.054. Epub 2016 May 19.

11.

A ketogenic diet increases transport and oxidation of ketone bodies in RG2 and 9L gliomas without affecting tumor growth.

De Feyter HM, Behar KL, Rao JU, Madden-Hennessey K, Ip KL, Hyder F, Drewes LR, Geschwind JF, de Graaf RA, Rothman DL.

Neuro Oncol. 2016 Aug;18(8):1079-87. doi: 10.1093/neuonc/now088. Epub 2016 May 3.

12.

Regulation of Monocarboxylic Acid Transporter 1 Trafficking by the Canonical Wnt/β-Catenin Pathway in Rat Brain Endothelial Cells Requires Cross-talk with Notch Signaling.

Liu Z, Sneve M, Haroldson TA, Smith JP, Drewes LR.

J Biol Chem. 2016 Apr 8;291(15):8059-69. doi: 10.1074/jbc.M115.710277. Epub 2016 Feb 12.

13.

Advances in brain barriers and brain fluid research and news from Fluids and Barriers of the CNS.

Drewes LR, Jones HC, Keep RF.

Fluids Barriers CNS. 2016 Jan 28;13:1. doi: 10.1186/s12987-016-0026-1.

14.

Monocarboxylate transporter 1 inhibitors as potential anticancer agents.

Gurrapu S, Jonnalagadda SK, Alam MA, Nelson GL, Sneve MG, Drewes LR, Mereddy VR.

ACS Med Chem Lett. 2015 Mar 19;6(5):558-61. doi: 10.1021/acsmedchemlett.5b00049. eCollection 2015 May 14.

15.

News from the editors of Fluids and Barriers of the CNS.

Drewes LR, Jones HC, Keep RF.

Fluids Barriers CNS. 2014 Jun 17;11:13. doi: 10.1186/2045-8118-11-13. eCollection 2014.

16.

Frizzled fissure to improve central nervous system drug delivery?

Drewes LR.

J Cereb Blood Flow Metab. 2014 Aug;34(8):1257. doi: 10.1038/jcbfm.2014.98. Epub 2014 Jun 4.

17.

Immunologic privilege in the central nervous system and the blood-brain barrier.

Muldoon LL, Alvarez JI, Begley DJ, Boado RJ, Del Zoppo GJ, Doolittle ND, Engelhardt B, Hallenbeck JM, Lonser RR, Ohlfest JR, Prat A, Scarpa M, Smeyne RJ, Drewes LR, Neuwelt EA.

J Cereb Blood Flow Metab. 2013 Jan;33(1):13-21. doi: 10.1038/jcbfm.2012.153. Epub 2012 Oct 17. Review.

18.

Regulation of Mct1 by cAMP-dependent internalization in rat brain endothelial cells.

Smith JP, Uhernik AL, Li L, Liu Z, Drewes LR.

Brain Res. 2012 Oct 22;1480:1-11. doi: 10.1016/j.brainres.2012.08.026. Epub 2012 Aug 20.

19.

Making connexons in the neurovascular unit.

Drewes LR.

J Cereb Blood Flow Metab. 2012 Aug;32(8):1455-6. doi: 10.1038/jcbfm.2012.44. Epub 2012 Apr 4. No abstract available.

20.

Engaging neuroscience to advance translational research in brain barrier biology.

Neuwelt EA, Bauer B, Fahlke C, Fricker G, Iadecola C, Janigro D, Leybaert L, Molnár Z, O'Donnell ME, Povlishock JT, Saunders NR, Sharp F, Stanimirovic D, Watts RJ, Drewes LR.

Nat Rev Neurosci. 2011 Mar;12(3):169-82. doi: 10.1038/nrn2995. Review.

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