Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 148

1.

Structural and biochemical investigations of the [4Fe-4S] cluster-containing fumarate hydratase from Leishmania major.

Feliciano PR, Drennan CL.

Biochemistry. 2019 Nov 19. doi: 10.1021/acs.biochem.9b00923. [Epub ahead of print]

PMID:
31743022
2.

Structural insight into metallocofactor maturation in carbon monoxide dehydrogenase.

Wittenborn EC, Cohen SE, Merrouch M, Léger C, Fourmond V, Dementin S, Drennan CL.

J Biol Chem. 2019 Aug 30;294(35):13017-13026. doi: 10.1074/jbc.RA119.009610. Epub 2019 Jul 11.

PMID:
31296570
3.

Solution structure and biochemical characterization of a spare part protein that restores activity to an oxygen-damaged glycyl radical enzyme.

Bowman SEJ, Backman LRF, Bjork RE, Andorfer MC, Yori S, Caruso A, Stultz CM, Drennan CL.

J Biol Inorg Chem. 2019 Sep;24(6):817-829. doi: 10.1007/s00775-019-01681-2. Epub 2019 Jun 27.

PMID:
31250200
4.

X-ray crystallography-based structural elucidation of enzyme-bound intermediates along the 1-deoxy-d-xylulose 5-phosphate synthase reaction coordinate.

Chen PY, DeColli AA, Freel Meyers CL, Drennan CL.

J Biol Chem. 2019 Aug 16;294(33):12405-12414. doi: 10.1074/jbc.RA119.009321. Epub 2019 Jun 25.

PMID:
31239351
5.

DNA repair enzymes ALKBH2, ALKBH3, and AlkB oxidize 5-methylcytosine to 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine in vitro.

Bian K, Lenz SAP, Tang Q, Chen F, Qi R, Jost M, Drennan CL, Essigmann JM, Wetmore SD, Li D.

Nucleic Acids Res. 2019 Jun 20;47(11):5522-5529. doi: 10.1093/nar/gkz395.

6.

A reverse TCA cycle 2-oxoacid:ferredoxin oxidoreductase that makes C-C bonds from CO2.

Chen PY, Li B, Drennan CL, Elliott SJ.

Joule. 2019 Feb 20;3(2):595-611. doi: 10.1016/j.joule.2018.12.006. Epub 2019 Jan 4.

PMID:
31080943
7.

A widely distributed diheme enzyme from Burkholderia that displays an atypically stable bis-Fe(IV) state.

Rizzolo K, Cohen SE, Weitz AC, López Muñoz MM, Hendrich MP, Drennan CL, Elliott SJ.

Nat Commun. 2019 Mar 7;10(1):1101. doi: 10.1038/s41467-019-09020-4.

8.

Crystal Structures of Fumarate Hydratases from Leishmania major in a Complex with Inhibitor 2-Thiomalate.

Feliciano PR, Drennan CL, Nonato MC.

ACS Chem Biol. 2019 Feb 15;14(2):266-275. doi: 10.1021/acschembio.8b00972. Epub 2019 Jan 24.

PMID:
30645090
9.

Structure-Guided Identification of a Small Molecule That Inhibits Anaerobic Choline Metabolism by Human Gut Bacteria.

Orman M, Bodea S, Funk MA, Campo AM, Bollenbach M, Drennan CL, Balskus EP.

J Am Chem Soc. 2019 Jan 9;141(1):33-37. doi: 10.1021/jacs.8b04883. Epub 2018 Dec 17.

PMID:
30557011
10.

Crystal structure of AdoMet radical enzyme 7-carboxy-7-deazaguanine synthase from Escherichia coli suggests how modifications near [4Fe-4S] cluster engender flavodoxin specificity.

Grell TAJ, Bell BN, Nguyen C, Dowling DP, Bruender NA, Bandarian V, Drennan CL.

Protein Sci. 2019 Jan;28(1):202-215. doi: 10.1002/pro.3529.

PMID:
30341796
11.

Redox-dependent rearrangements of the NiFeS cluster of carbon monoxide dehydrogenase.

Wittenborn EC, Merrouch M, Ueda C, Fradale L, Léger C, Fourmond V, Pandelia ME, Dementin S, Drennan CL.

Elife. 2018 Oct 2;7. pii: e39451. doi: 10.7554/eLife.39451.

12.

Structural and spectroscopic analyses of the sporulation killing factor biosynthetic enzyme SkfB, a bacterial AdoMet radical sactisynthase.

Grell TAJ, Kincannon WM, Bruender NA, Blaesi EJ, Krebs C, Bandarian V, Drennan CL.

J Biol Chem. 2018 Nov 9;293(45):17349-17361. doi: 10.1074/jbc.RA118.005369. Epub 2018 Sep 14.

13.

Metalloenzymes in natural product biosynthetic pathways.

Ryan KS, Drennan CL.

Nat Prod Rep. 2018 Jul 18;35(7):612-614. doi: 10.1039/c8np90023j. No abstract available.

PMID:
30009301
14.

A Rich Man, Poor Man Story of S-Adenosylmethionine and Cobalamin Revisited.

Bridwell-Rabb J, Grell TAJ, Drennan CL.

Annu Rev Biochem. 2018 Jun 20;87:555-584. doi: 10.1146/annurev-biochem-062917-012500. Review.

PMID:
29925255
15.

Isonitrile Formation by a Non-Heme Iron(II)-Dependent Oxidase/Decarboxylase.

Harris NC, Born DA, Cai W, Huang Y, Martin J, Khalaf R, Drennan CL, Zhang W.

Angew Chem Int Ed Engl. 2018 Jul 26;57(31):9707-9710. doi: 10.1002/anie.201804307. Epub 2018 Jul 3.

16.

Biophysical Examination of the Calcium-Modulated Nickel-Binding Properties of Human Calprotectin Reveals Conformational Change in the EF-Hand Domains and His3Asp Site.

Nakashige TG, Bowman SEJ, Zygiel EM, Drennan CL, Nolan EM.

Biochemistry. 2018 Jul 17;57(28):4155-4164. doi: 10.1021/acs.biochem.8b00415. Epub 2018 Jun 26.

17.

Biochemical and Structural Characterization of a Schiff Base in the Radical-Mediated Biosynthesis of 4-Demethylwyosine by TYW1.

Grell TAJ, Young AP, Drennan CL, Bandarian V.

J Am Chem Soc. 2018 Jun 6;140(22):6842-6852. doi: 10.1021/jacs.8b01493. Epub 2018 May 24.

18.

Disruption of an oligomeric interface prevents allosteric inhibition of Escherichia coli class Ia ribonucleotide reductase.

Chen PY, Funk MA, Brignole EJ, Drennan CL.

J Biol Chem. 2018 Jun 29;293(26):10404-10412. doi: 10.1074/jbc.RA118.002569. Epub 2018 Apr 26.

19.

Binding site for coenzyme A revealed in the structure of pyruvate:ferredoxin oxidoreductase from Moorella thermoacetica.

Chen PY, Aman H, Can M, Ragsdale SW, Drennan CL.

Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):3846-3851. doi: 10.1073/pnas.1722329115. Epub 2018 Mar 26.

20.

3.3-Å resolution cryo-EM structure of human ribonucleotide reductase with substrate and allosteric regulators bound.

Brignole EJ, Tsai KL, Chittuluru J, Li H, Aye Y, Penczek PA, Stubbe J, Drennan CL, Asturias F.

Elife. 2018 Feb 20;7. pii: e31502. doi: 10.7554/eLife.31502.

Supplemental Content

Loading ...
Support Center