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Items: 1 to 20 of 335

1.

FAF1 phosphorylation by AKT accumulates TGF-β type II receptor and drives breast cancer metastasis.

Xie F, Jin K, Shao L, Fan Y, Tu Y, Li Y, Yang B, van Dam H, Ten Dijke P, Weng H, Dooley S, Wang S, Jia J, Jin J, Zhou F, Zhang L.

Nat Commun. 2017 Apr 26;8:15021. doi: 10.1038/ncomms15021.

2.

BMP-9 interferes with liver regeneration and promotes liver fibrosis.

Breitkopf-Heinlein K, Meyer C, König C, Gaitantzi H, Addante A, Thomas M, Wiercinska E, Cai C, Li Q, Wan F, Hellerbrand C, Valous NA, Hahnel M, Ehlting C, Bode JG, Müller-Bohl S, Klingmüller U, Altenöder J, Ilkavets I, Goumans MJ, Hawinkels LJ, Lee SJ, Wieland M, Mogler C, Ebert MP, Herrera B, Augustin H, Sánchez A, Dooley S, Ten Dijke P.

Gut. 2017 May;66(5):939-954. doi: 10.1136/gutjnl-2016-313314. Epub 2017 Mar 23.

PMID:
28336518
3.

Hydrogen sulfide promotes autophagy of hepatocellular carcinoma cells through the PI3K/Akt/mTOR signaling pathway.

Wang SS, Chen YH, Chen N, Wang LJ, Chen DX, Weng HL, Dooley S, Ding HG.

Cell Death Dis. 2017 Mar 23;8(3):e2688. doi: 10.1038/cddis.2017.18.

4.

Robust detection and segmentation of cell nuclei in biomedical images based on a computational topology framework.

Rojas-Moraleda R, Xiong W, Halama N, Breitkopf-Heinlein K, Dooley S, Salinas L, Heermann DW, Valous NA.

Med Image Anal. 2017 May;38:90-103. doi: 10.1016/j.media.2017.02.009. Epub 2017 Mar 6.

PMID:
28314191
5.

Quantification of substrate and cellular strains in stretchable 3D cell cultures: an experimental and computational framework.

González-Avalos P, Mürnseer M, Deeg J, Bachmann A, Spatz J, Dooley S, Eils R, Gladilin E.

J Microsc. 2017 May;266(2):115-125. doi: 10.1111/jmi.12520. Epub 2017 Mar 7.

PMID:
28267878
6.

Pharmacokinetics and pharmacodynamics of buprenorphine and sustained-release buprenorphine after administration to adult alpacas.

Dooley SB, Aarnes TK, Lakritz J, Lerche P, Bednarski RM, Hubbell JA.

Am J Vet Res. 2017 Mar;78(3):321-329. doi: 10.2460/ajvr.78.3.321.

PMID:
28240955
7.

Global Transcriptional Response of Human Liver Cells to Ethanol Stress of Different Strength Reveals Hormetic Behavior.

Schmidt-Heck W, Wönne EC, Hiller T, Menzel U, Koczan D, Damm G, Seehofer D, Knöspel F, Freyer N, Guthke R, Dooley S, Zeilinger K.

Alcohol Clin Exp Res. 2017 May;41(5):883-894. doi: 10.1111/acer.13361. Epub 2017 Mar 27.

PMID:
28226195
8.

Hepatocyte-specific Smad7 deletion accelerates DEN-induced HCC via activation of STAT3 signaling in mice.

Feng T, Dzieran J, Yuan X, Dropmann A, Maass T, Teufel A, Marhenke S, Gaiser T, Rückert F, Kleiter I, Kanzler S, Ebert MP, Vogel A, Ten Dijke P, Dooley S, Meindl-Beinker NM.

Oncogenesis. 2017 Jan 30;6(1):e294. doi: 10.1038/oncsis.2016.85.

9.

Quantitative and integrative analysis of paracrine hepatocyte activation by nonparenchymal cells upon lipopolysaccharide induction.

Beuke K, Schildberg FA, Pinna F, Albrecht U, Liebe R, Bissinger M, Schirmacher P, Dooley S, Bode JG, Knolle PA, Kummer U, Breuhahn K, Sahle S.

FEBS J. 2017 Mar;284(5):796-813. doi: 10.1111/febs.14022. Epub 2017 Feb 17.

PMID:
28109179
10.

Blood-based detection of RAS mutations to guide anti-EGFR therapy in colorectal cancer patients: concordance of results from circulating tumor DNA and tissue-based RAS testing.

Schmiegel W, Scott RJ, Dooley S, Lewis W, Meldrum CJ, Pockney P, Draganic B, Smith S, Hewitt C, Philimore H, Lucas A, Shi E, Namdarian K, Chan T, Acosta D, Ping-Chang S, Tannapfel A, Reinacher-Schick A, Uhl W, Teschendorf C, Wolters H, Stern J, Viebahn R, Friess H, Janssen KP, Nitsche U, Slotta-Huspenina J, Pohl M, Vangala D, Baraniskin A, Dockhorn-Dworniczak B, Hegewisch-Becker S, Ronga P, Edelstein DL, Jones FS, Hahn S, Fox SB.

Mol Oncol. 2017 Feb;11(2):208-219. doi: 10.1002/1878-0261.12023. Epub 2017 Jan 20.

11.

Caveolin-1 in the regulation of cell metabolism: a cancer perspective.

Nwosu ZC, Ebert MP, Dooley S, Meyer C.

Mol Cancer. 2016 Nov 16;15(1):71. Review.

12.

Definitive IMRT for Stage III Thymic Carcinoma: A Brief Report and Literature Review.

Dooley SA, Anderson CM.

Front Oncol. 2016 Oct 24;6:219. eCollection 2016.

13.

Orphan nuclear receptor SHP regulates iron metabolism through inhibition of BMP6-mediated hepcidin expression.

Kim DK, Kim YH, Jung YS, Kim KS, Jeong JH, Lee YS, Yuk JM, Oh BC, Choy HE, Dooley S, Muckenthaler MU, Lee CH, Choi HS.

Sci Rep. 2016 Sep 30;6:34630. doi: 10.1038/srep34630.

14.

Maternal and Neonatal Morbidity for Women Who Would Be Added to the Diagnosis of GDM Using IADPSG Criteria: A Secondary Analysis of the Hyperglycemia and Adverse Pregnancy Outcome Study.

Waters TP, Dyer AR, Scholtens DM, Dooley SL, Herer E, Lowe LP, Oats JJ, Persson B, Sacks DA, Metzger BE, Catalano PM; HAPO Cooperative Study Research Group..

Diabetes Care. 2016 Dec;39(12):2204-2210. Epub 2016 Sep 15.

PMID:
27634392
15.

BMP9 a possible alternative drug for the recently withdrawn BMP7? New perspectives for (re-)implementation by personalized medicine.

Sreekumar V, Aspera-Werz RH, Tendulkar G, Reumann MK, Freude T, Breitkopf-Heinlein K, Dooley S, Pscherer S, Ochs BG, Flesch I, Hofmann V, Nussler AK, Ehnert S.

Arch Toxicol. 2017 Mar;91(3):1353-1366. doi: 10.1007/s00204-016-1796-6. Epub 2016 Jul 9.

PMID:
27394662
16.

Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue.

Godoy P, Widera A, Schmidt-Heck W, Campos G, Meyer C, Cadenas C, Reif R, Stöber R, Hammad S, Pütter L, Gianmoena K, Marchan R, Ghallab A, Edlund K, Nüssler A, Thasler WE, Damm G, Seehofer D, Weiss TS, Dirsch O, Dahmen U, Gebhardt R, Chaudhari U, Meganathan K, Sachinidis A, Kelm J, Hofmann U, Zahedi RP, Guthke R, Blüthgen N, Dooley S, Hengstler JG.

Arch Toxicol. 2016 Oct;90(10):2513-29. doi: 10.1007/s00204-016-1761-4. Epub 2016 Jun 23.

17.

Evolving Insights on Metabolism, Autophagy, and Epigenetics in Liver Myofibroblasts.

Nwosu ZC, Alborzinia H, Wölfl S, Dooley S, Liu Y.

Front Physiol. 2016 Jun 1;7:191. doi: 10.3389/fphys.2016.00191. eCollection 2016. Review.

18.

Delta-Like Ligand 4 Modulates Liver Damage by Down-Regulating Chemokine Expression.

Shen Z, Liu Y, Dewidar B, Hu J, Park O, Feng T, Xu C, Yu C, Li Q, Meyer C, Ilkavets I, Müller A, Stump-Guthier C, Munker S, Liebe R, Zimmer V, Lammert F, Mertens PR, Li H, Ten Dijke P, Augustin HG, Li J, Gao B, Ebert MP, Dooley S, Li Y, Weng HL.

Am J Pathol. 2016 Jul;186(7):1874-89. doi: 10.1016/j.ajpath.2016.03.010. Epub 2016 May 10.

PMID:
27171900
19.

Vitamin C enhances epigenetic modifications induced by 5-azacytidine and cell cycle arrest in the hepatocellular carcinoma cell lines HLE and Huh7.

Sajadian SO, Tripura C, Samani FS, Ruoss M, Dooley S, Baharvand H, Nussler AK.

Clin Epigenetics. 2016 Apr 30;8:46. doi: 10.1186/s13148-016-0213-6. eCollection 2016.

20.

Transforming Growth Factor β1 (TGF-β1) Activates Hepcidin mRNA Expression in Hepatocytes.

Chen S, Feng T, Vujić Spasić M, Altamura S, Breitkopf-Heinlein K, Altenöder J, Weiss TS, Dooley S, Muckenthaler MU.

J Biol Chem. 2016 Jun 17;291(25):13160-74. doi: 10.1074/jbc.M115.691543. Epub 2016 Apr 27.

PMID:
27129231

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