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Items: 1 to 20 of 133


HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning.

Ferrari A, Longo R, Fiorino E, Silva R, Mitro N, Cermenati G, Gilardi F, Desvergne B, Andolfo A, Magagnotti C, Caruso D, Fabiani E, Hiebert SW, Crestani M.

Nat Commun. 2017 Jul 21;8(1):93. doi: 10.1038/s41467-017-00182-7.


From chronic overnutrition to metaflammation and insulin resistance: adipose tissue and liver contributions.

Caputo T, Gilardi F, Desvergne B.

FEBS Lett. 2017 Jul 5. doi: 10.1002/1873-3468.12742. [Epub ahead of print] Review.


Diurnal regulation of RNA polymerase III transcription is under the control of both the feeding-fasting response and the circadian clock.

Mange F, Praz V, Migliavacca E, Willis IM, Schütz F, Hernandez N; CycliX Consortium.

Genome Res. 2017 Jun;27(6):973-984. doi: 10.1101/gr.217521.116. Epub 2017 Mar 24.


Nephropathy in Pparg-null mice highlights PPARγ systemic activities in metabolism and in the immune system.

Toffoli B, Gilardi F, Winkler C, Soderberg M, Kowalczuk L, Arsenijevic Y, Bamberg K, Bonny O, Desvergne B.

PLoS One. 2017 Feb 9;12(2):e0171474. doi: 10.1371/journal.pone.0171474. eCollection 2017.


PPARγ controls pregnancy outcome through activation of EG-VEGF: new insights into the mechanism of placental development.

Garnier V, Traboulsi W, Salomon A, Brouillet S, Fournier T, Winkler C, Desvergne B, Hoffmann P, Zhou QY, Congiu C, Onnis V, Benharouga M, Feige JJ, Alfaidy N.

Am J Physiol Endocrinol Metab. 2015 Aug 15;309(4):E357-69. doi: 10.1152/ajpendo.00093.2015. Epub 2015 Jun 16.


Integrative and systemic approaches for evaluating PPARβ/δ (PPARD) function.

Giordano Attianese GM, Desvergne B.

Nucl Recept Signal. 2015 Apr 27;13:e001. doi: 10.1621/nrs.13001. eCollection 2015. Review.


Design, synthesis and biological evaluation of a class of bioisosteric oximes of the novel dual peroxisome proliferator-activated receptor α/γ ligand LT175.

Piemontese L, Fracchiolla G, Carrieri A, Parente M, Laghezza A, Carbonara G, Sblano S, Tauro M, Gilardi F, Tortorella P, Lavecchia A, Crestani M, Desvergne B, Loiodice F.

Eur J Med Chem. 2015 Jan 27;90:583-94. doi: 10.1016/j.ejmech.2014.11.044. Epub 2014 Nov 24.


Impaired musculoskeletal response to age and exercise in PPARβ(-/-) diabetic mice.

Fu H, Desvergne B, Ferrari S, Bonnet N.

Endocrinology. 2014 Dec;155(12):4686-96. doi: 10.1210/en.2014-1585. Epub 2014 Oct 3.


RXRs: collegial partners.

Gilardi F, Desvergne B.

Subcell Biochem. 2014;70:75-102. doi: 10.1007/978-94-017-9050-5_5. Review.


Quantifying ChIP-seq data: a spiking method providing an internal reference for sample-to-sample normalization.

Bonhoure N, Bounova G, Bernasconi D, Praz V, Lammers F, Canella D, Willis IM, Herr W, Hernandez N, Delorenzi M; CycliX Consortium.

Genome Res. 2014 Jul;24(7):1157-68. doi: 10.1101/gr.168260.113. Epub 2014 Apr 7.


Genome-wide analysis of SREBP1 activity around the clock reveals its combined dependency on nutrient and circadian signals.

Gilardi F, Migliavacca E, Naldi A, Baruchet M, Canella D, Le Martelot G, Guex N, Desvergne B; CycliX Consortium.

PLoS Genet. 2014 Mar 6;10(3):e1004155. doi: 10.1371/journal.pgen.1004155. eCollection 2014 Mar.


SOCS3 transactivation by PPARγ prevents IL-17-driven cancer growth.

Berger H, Végran F, Chikh M, Gilardi F, Ladoire S, Bugaut H, Mignot G, Chalmin F, Bruchard M, Derangère V, Chevriaux A, Rébé C, Ryffel B, Pot C, Hichami A, Desvergne B, Ghiringhelli F, Apetoh L.

Cancer Res. 2013 Jun 15;73(12):3578-90. doi: 10.1158/0008-5472.CAN-12-4018. Epub 2013 Apr 25.


PPARβ/δ governs Wnt signaling and bone turnover.

Scholtysek C, Katzenbeisser J, Fu H, Uderhardt S, Ipseiz N, Stoll C, Zaiss MM, Stock M, Donhauser L, Böhm C, Kleyer A, Hess A, Engelke K, David JP, Djouad F, Tuckermann JP, Desvergne B, Schett G, Krönke G.

Nat Med. 2013 May;19(5):608-13. doi: 10.1038/nm.3146. Epub 2013 Mar 31.


Genome-wide RNA polymerase II profiles and RNA accumulation reveal kinetics of transcription and associated epigenetic changes during diurnal cycles.

Le Martelot G, Canella D, Symul L, Migliavacca E, Gilardi F, Liechti R, Martin O, Harshman K, Delorenzi M, Desvergne B, Herr W, Deplancke B, Schibler U, Rougemont J, Guex N, Hernandez N, Naef F; CycliX Consortium.

PLoS Biol. 2012;10(11):e1001442. doi: 10.1371/journal.pbio.1001442. Epub 2012 Nov 27.


Cell autonomous lipin 1 function is essential for development and maintenance of white and brown adipose tissue.

Nadra K, Médard JJ, Mul JD, Han GS, Grès S, Pende M, Metzger D, Chambon P, Cuppen E, Saulnier-Blache JS, Carman GM, Desvergne B, Chrast R.

Mol Cell Biol. 2012 Dec;32(23):4794-810. doi: 10.1128/MCB.00512-12. Epub 2012 Oct 1.


Epineurial adipocytes are dispensable for Schwann cell myelination.

Nadra K, Médard JJ, Quignodon L, Verheijen MH, Desvergne B, Chrast R.

J Neurochem. 2012 Dec;123(5):662-7. doi: 10.1111/j.1471-4159.2012.07896.x. Epub 2012 Oct 10.


Morbillivirus glycoprotein expression induces ER stress, alters Ca2+ homeostasis and results in the release of vasostatin.

Brunner JM, Plattet P, Doucey MA, Rosso L, Curie T, Montagner A, Wittek R, Vandelvelde M, Zurbriggen A, Hirling H, Desvergne B.

PLoS One. 2012;7(3):e32803. doi: 10.1371/journal.pone.0032803. Epub 2012 Mar 5.


A multiplicity of factors contributes to selective RNA polymerase III occupancy of a subset of RNA polymerase III genes in mouse liver.

Canella D, Bernasconi D, Gilardi F, LeMartelot G, Migliavacca E, Praz V, Cousin P, Delorenzi M, Hernandez N; CycliX Consortium.

Genome Res. 2012 Apr;22(4):666-80. doi: 10.1101/gr.130286.111. Epub 2012 Jan 27.


NCoR1 is a conserved physiological modulator of muscle mass and oxidative function.

Yamamoto H, Williams EG, Mouchiroud L, Cantó C, Fan W, Downes M, Héligon C, Barish GD, Desvergne B, Evans RM, Schoonjans K, Auwerx J.

Cell. 2011 Nov 11;147(4):827-39. doi: 10.1016/j.cell.2011.10.017.


Endocrine disruptors: from endocrine to metabolic disruption.

Casals-Casas C, Desvergne B.

Annu Rev Physiol. 2011;73:135-62. doi: 10.1146/annurev-physiol-012110-142200. Review.


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