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Persistent lymphopenia is a risk factor for ICU-acquired infections and for death in ICU patients with sustained hypotension at admission.

Adrie C, Lugosi M, Sonneville R, Souweine B, Ruckly S, Cartier JC, Garrouste-Orgeas M, Schwebel C, Timsit JF; OUTCOMEREA study group.

Ann Intensive Care. 2017 Dec;7(1):30. doi: 10.1186/s13613-017-0242-0. Epub 2017 Mar 17.


Colonization and infection with extended-spectrum β-lactamase-producing Enterobacteriaceae in ICU patients: what impact on outcomes and carbapenem exposure?

Barbier F, Pommier C, Essaied W, Garrouste-Orgeas M, Schwebel C, Ruckly S, Dumenil AS, Lemiale V, Mourvillier B, Clec'h C, Darmon M, Laurent V, Marcotte G, Lucet JC, Souweine B, Zahar JR, Timsit JF; OUTCOMEREA Study Group.

J Antimicrob Chemother. 2016 Apr;71(4):1088-97. doi: 10.1093/jac/dkv423. Epub 2016 Jan 10.


Decreased Risk of Ventilator-Associated Pneumonia in Sepsis Due to Intra-Abdominal Infection.

Philippart F, Bouroche G, Timsit JF, Garrouste-Orgeas M, Azoulay E, Darmon M, Adrie C, Allaouchiche B, Ara-Somohano C, Ruckly S, Dumenil AS, Souweine B, Goldgran-Toledano D, Bouadma L, Misset B; Outcomerea study group.

PLoS One. 2015 Sep 4;10(9):e0137262. doi: 10.1371/journal.pone.0137262. eCollection 2015.


Sepsis severe or septic shock: outcome according to immune status and immunodeficiency profile.

Tolsma V, Schwebel C, Azoulay E, Darmon M, Souweine B, Vesin A, Goldgran-Toledano D, Lugosi M, Jamali S, Cheval C, Adrie C, Kallel H, Descorps-Declere A, Garrouste-Orgeas M, Bouadma L, Timsit JF.

Chest. 2014 Nov;146(5):1205-1213. doi: 10.1378/chest.13-2618.


Safety of intrahospital transport in ventilated critically ill patients: a multicenter cohort study*.

Schwebel C, Clec'h C, Magne S, Minet C, Garrouste-Orgeas M, Bonadona A, Dumenil AS, Jamali S, Kallel H, Goldgran-Toledano D, Marcotte G, Azoulay E, Darmon M, Ruckly S, Souweine B, Timsit JF; OUTCOMEREA Study Group.

Crit Care Med. 2013 Aug;41(8):1919-28. doi: 10.1097/CCM.0b013e31828a3bbd.


Pseudomonas aeruginosa ventilator-associated pneumonia. predictive factors of treatment failure.

Planquette B, Timsit JF, Misset BY, Schwebel C, Azoulay E, Adrie C, Vesin A, Jamali S, Zahar JR, Allaouchiche B, Souweine B, Darmon M, Dumenil AS, Goldgran-Toledano D, Mourvillier BH, Bédos JP; OUTCOMEREA Study Group.

Am J Respir Crit Care Med. 2013 Jul 1;188(1):69-76. doi: 10.1164/rccm.201210-1897OC.


A model to predict short-term death or readmission after intensive care unit discharge.

Ouanes I, Schwebel C, Français A, Bruel C, Philippart F, Vesin A, Soufir L, Adrie C, Garrouste-Orgeas M, Timsit JF, Misset B; Outcomerea Study Group.

J Crit Care. 2012 Aug;27(4):422.e1-9. doi: 10.1016/j.jcrc.2011.08.003. Epub 2011 Dec 14.


Designing and conducting a randomized trial for pandemic critical illness: the 2009 H1N1 influenza pandemic.

Annane D, Antona M, Lehmann B, Kedzia C, Chevret S; CORTIFLU Investigators; CRICs; AZUREA; REVA/SRLF networks.

Intensive Care Med. 2012 Jan;38(1):29-39. doi: 10.1007/s00134-011-2409-8. Epub 2011 Nov 26.


Attributable mortality of ventilator-associated pneumonia: a reappraisal using causal analysis.

Bekaert M, Timsit JF, Vansteelandt S, Depuydt P, Vésin A, Garrouste-Orgeas M, Decruyenaere J, Clec'h C, Azoulay E, Benoit D; Outcomerea Study Group.

Am J Respir Crit Care Med. 2011 Nov 15;184(10):1133-9. doi: 10.1164/rccm.201105-0867OC.


Multiple-center evaluation of mortality associated with acute kidney injury in critically ill patients: a competing risks analysis.

Clec'h C, Gonzalez F, Lautrette A, Nguile-Makao M, Garrouste-Orgeas M, Jamali S, Golgran-Toledano D, Descorps-Declere A, Chemouni F, Hamidfar-Roy R, Azoulay E, Timsit JF.

Crit Care. 2011;15(3):R128. doi: 10.1186/cc10241. Epub 2011 May 17.


Outcomes in severe sepsis and patients with septic shock: pathogen species and infection sites are not associated with mortality.

Zahar JR, Timsit JF, Garrouste-Orgeas M, Français A, Vesin A, Descorps-Declere A, Dubois Y, Souweine B, Haouache H, Goldgran-Toledano D, Allaouchiche B, Azoulay E, Adrie C.

Crit Care Med. 2011 Aug;39(8):1886-95. doi: 10.1097/CCM.0b013e31821b827c. Erratum in: Crit Care Med. 2011 Oct;39(10):2392. Vesim, Aurélien [corrected to Vesin, Aurélien].


Impact of ureido/carboxypenicillin resistance on the prognosis of ventilator-associated pneumonia due to Pseudomonas aeruginosa.

Kaminski C, Timsit JF, Dubois Y, Zahar JR, Garrouste-Orgeas M, Vesin A, Azoulay E, Feger C, Dumenil AS, Adrie C, Cohen Y, Allaouchiche B; OUTCOMEREA study group.

Crit Care. 2011;15(2):R112. doi: 10.1186/cc10136. Epub 2011 Apr 11.


Selected medical errors in the intensive care unit: results of the IATROREF study: parts I and II.

Garrouste-Orgeas M, Timsit JF, Vesin A, Schwebel C, Arnodo P, Lefrant JY, Souweine B, Tabah A, Charpentier J, Gontier O, Fieux F, Mourvillier B, Troché G, Reignier J, Dumay MF, Azoulay E, Reignier B, Carlet J, Soufir L; OUTCOMEREA Study Group.

Am J Respir Crit Care Med. 2010 Jan 15;181(2):134-42. doi: 10.1164/rccm.200812-1820OC. Epub 2009 Oct 29.


Study of prone positioning to reduce ventilator-associated pneumonia in hypoxaemic patients.

Mounier R, Adrie C, Français A, Garrouste-Orgeas M, Cheval C, Allaouchiche B, Jamali S, Dinh-Xuan AT, Goldgran-Toledano D, Cohen Y, Azoulay E, Timsit JF, Ricard JD; OUTCOMEREA Study Group.

Eur Respir J. 2010 Apr;35(4):795-804. doi: 10.1183/09031936.00057509. Epub 2009 Sep 9.


Prevalence and factors of intensive care unit conflicts: the conflicus study.

Azoulay E, Timsit JF, Sprung CL, Soares M, Rusinová K, Lafabrie A, Abizanda R, Svantesson M, Rubulotta F, Ricou B, Benoit D, Heyland D, Joynt G, Français A, Azeivedo-Maia P, Owczuk R, Benbenishty J, de Vita M, Valentin A, Ksomos A, Cohen S, Kompan L, Ho K, Abroug F, Kaarlola A, Gerlach H, Kyprianou T, Michalsen A, Chevret S, Schlemmer B; Conflicus Study Investigators and for the Ethics Section of the European Society of Intensive Care Medicine.

Am J Respir Crit Care Med. 2009 Nov 1;180(9):853-60. doi: 10.1164/rccm.200810-1614OC. Epub 2009 Jul 30.


Model for predicting short-term mortality of severe sepsis.

Adrie C, Francais A, Alvarez-Gonzalez A, Mounier R, Azoulay E, Zahar JR, Clec'h C, Goldgran-Toledano D, Hammer L, Descorps-Declere A, Jamali S, Timsit JF; Outcomerea Study Group.

Crit Care. 2009;13(3):R72. doi: 10.1186/cc7881. Epub 2009 May 19.


Comparison of two versions of the Vigileo-FloTrac system (1.03 and 1.07) for stroke volume estimation: a multicentre, blinded comparison with oesophageal Doppler measurements.

Chatti R, de Rudniki S, Marqué S, Dumenil AS, Descorps-Declère A, Cariou A, Duranteau J, Aout M, Vicaut E, Cholley BP.

Br J Anaesth. 2009 Apr;102(4):463-9. doi: 10.1093/bja/aep020. Epub 2009 Feb 25.


Using pulse pressure variation in patients with acute respiratory distress syndrome.

Michard F, Descorps-Declere A, Lopes MR.

Crit Care Med. 2008 Oct;36(10):2946-8. doi: 10.1097/CCM.0b013e318187b6fd. No abstract available.


Impact of adverse events on outcomes in intensive care unit patients.

Garrouste Orgeas M, Timsit JF, Soufir L, Tafflet M, Adrie C, Philippart F, Zahar JR, Clec'h C, Goldran-Toledano D, Jamali S, Dumenil AS, Azoulay E, Carlet J; Outcomerea Study Group.

Crit Care Med. 2008 Jul;36(7):2041-7. doi: 10.1097/CCM.0b013e31817b879c.


Does catheter-associated urinary tract infection increase mortality in critically ill patients?

Clec'h C, Schwebel C, Français A, Toledano D, Fosse JP, Garrouste-Orgeas M, Azoulay E, Adrie C, Jamali S, Descorps-Declere A, Nakache D, Timsit JF, Cohen Y; OutcomeRea Study Group.

Infect Control Hosp Epidemiol. 2007 Dec;28(12):1367-73. Epub 2007 Nov 1.


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