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Items: 1 to 20 of 141


Interdependency of EGF and GLP-2 Signaling in Attenuating Mucosal Atrophy in a Mouse Model of Parenteral Nutrition.

Feng Y, Demehri FR, Xiao W, Tsai YH, Jones JC, Brindley CD, Threadgill DW, Holst JJ, Hartmann B, Barrett TA, Teitelbaum DH, Dempsey PJ.

Cell Mol Gastroenterol Hepatol. 2017 Jan 17;3(3):447-468. doi: 10.1016/j.jcmgh.2016.12.005. eCollection 2017 May.


ErbB4 signaling stimulates pro-inflammatory macrophage apoptosis and limits colonic inflammation.

Schumacher MA, Hedl M, Abraham C, Bernard JK, Lozano PR, Hsieh JJ, Almohazey D, Bucar EB, Punit S, Dempsey PJ, Frey MR.

Cell Death Dis. 2017 Feb 23;8(2):e2622. doi: 10.1038/cddis.2017.42.


Advances in Interventional Oncology: Lung Cancer.

Dempsey PJ, Ridge CA, Solomon SB.

Cancer J. 2016 Nov/Dec;22(6):393-400.


Are Facultative Reserve ISCs the Cellular Origin of Familial Small Intestinal Neuroendocrine Tumors?

Dempsey PJ.

Gastroenterology. 2016 Jul;151(1):27-9. doi: 10.1053/j.gastro.2016.05.020. Epub 2016 May 27. No abstract available.


ADAM Proteases and Gastrointestinal Function.

Jones JC, Rustagi S, Dempsey PJ.

Annu Rev Physiol. 2016;78:243-76. doi: 10.1146/annurev-physiol-021014-071720. Epub 2015 Nov 19. Review.


Loss of ADAM17-Mediated Tumor Necrosis Factor Alpha Signaling in Intestinal Cells Attenuates Mucosal Atrophy in a Mouse Model of Parenteral Nutrition.

Feng Y, Tsai YH, Xiao W, Ralls MW, Stoeck A, Wilson CL, Raines EW, Teitelbaum DH, Dempsey PJ.

Mol Cell Biol. 2015 Nov;35(21):3604-21. doi: 10.1128/MCB.00143-15. Epub 2015 Aug 17.


Transcriptome-wide Analysis Reveals Hallmarks of Human Intestine Development and Maturation In Vitro and In Vivo.

Finkbeiner SR, Hill DR, Altheim CH, Dedhia PH, Taylor MJ, Tsai YH, Chin AM, Mahe MM, Watson CL, Freeman JJ, Nattiv R, Thomson M, Klein OD, Shroyer NF, Helmrath MA, Teitelbaum DH, Dempsey PJ, Spence JR.

Stem Cell Reports. 2015 Jun 3. pii: S2213-6711(15)00122-8. doi: 10.1016/j.stemcr.2015.04.010. [Epub ahead of print]


TPN-associated intestinal epithelial cell atrophy is modulated by TLR4/EGF signaling pathways.

Freeman JJ, Feng Y, Demehri FR, Dempsey PJ, Teitelbaum DH.

FASEB J. 2015 Jul;29(7):2943-58. doi: 10.1096/fj.14-269480. Epub 2015 Mar 17.


ADAM10 regulates Notch function in intestinal stem cells of mice.

Tsai YH, VanDussen KL, Sawey ET, Wade AW, Kasper C, Rakshit S, Bhatt RG, Stoeck A, Maillard I, Crawford HC, Samuelson LC, Dempsey PJ.

Gastroenterology. 2014 Oct;147(4):822-834.e13. doi: 10.1053/j.gastro.2014.07.003. Epub 2014 Jul 16.


N-cadherin promotes recruitment and migration of neural progenitor cells from the SVZ neural stem cell niche into demyelinated lesions.

Klingener M, Chavali M, Singh J, McMillan N, Coomes A, Dempsey PJ, Chen EI, Aguirre A.

J Neurosci. 2014 Jul 16;34(29):9590-606. doi: 10.1523/JNEUROSCI.3699-13.2014.


Jay J. Listinsky, MD, PhD.

Dempsey PJ.

Radiology. 2014 May;271(2):621. doi: 10.1148/radiol.14144006. No abstract available.


A Lactobacillus rhamnosus GG-derived soluble protein, p40, stimulates ligand release from intestinal epithelial cells to transactivate epidermal growth factor receptor.

Yan F, Liu L, Dempsey PJ, Tsai YH, Raines EW, Wilson CL, Cao H, Cao Z, Liu L, Polk DB.

J Biol Chem. 2013 Oct 18;288(42):30742-51. doi: 10.1074/jbc.M113.492397. Epub 2013 Sep 16.


Distinct TCR signaling pathways drive proliferation and cytokine production in T cells.

Guy CS, Vignali KM, Temirov J, Bettini ML, Overacre AE, Smeltzer M, Zhang H, Huppa JB, Tsai YH, Lobry C, Xie J, Dempsey PJ, Crawford HC, Aifantis I, Davis MM, Vignali DA.

Nat Immunol. 2013 Mar;14(3):262-70. doi: 10.1038/ni.2538. Epub 2013 Feb 3.


Constitutive α- and β-secretase cleavages of the amyloid precursor protein are partially coupled in neurons, but not in frequently used cell lines.

Colombo A, Wang H, Kuhn PH, Page R, Kremmer E, Dempsey PJ, Crawford HC, Lichtenthaler SF.

Neurobiol Dis. 2013 Jan;49:137-47. doi: 10.1016/j.nbd.2012.08.011. Epub 2012 Aug 24.


Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells.

VanDussen KL, Carulli AJ, Keeley TM, Patel SR, Puthoff BJ, Magness ST, Tran IT, Maillard I, Siebel C, Kolterud Å, Grosse AS, Gumucio DL, Ernst SA, Tsai YH, Dempsey PJ, Samuelson LC.

Development. 2012 Feb;139(3):488-97. doi: 10.1242/dev.070763. Epub 2011 Dec 21.


TNF-α converting enzyme-mediated ErbB4 transactivation by TNF promotes colonic epithelial cell survival.

Hilliard VC, Frey MR, Dempsey PJ, Peek RM Jr, Polk DB.

Am J Physiol Gastrointest Liver Physiol. 2011 Aug;301(2):G338-46. doi: 10.1152/ajpgi.00057.2011. Epub 2011 May 26.


The need for breast cancer screening in women undergoing elective breast surgery: an assessment of risk and risk factors for breast cancer in young women.

Sharabi SE, Bullocks JM, Dempsey PJ, Singletary SE.

Aesthet Surg J. 2010 Nov-Dec;30(6):821-31. doi: 10.1177/1090820X10386589.


Conditional gene targeting in mouse pancreatic ß-Cells: analysis of ectopic Cre transgene expression in the brain.

Wicksteed B, Brissova M, Yan W, Opland DM, Plank JL, Reinert RB, Dickson LM, Tamarina NA, Philipson LH, Shostak A, Bernal-Mizrachi E, Elghazi L, Roe MW, Labosky PA, Myers MG Jr, Gannon M, Powers AC, Dempsey PJ.

Diabetes. 2010 Dec;59(12):3090-8. doi: 10.2337/db10-0624. Epub 2010 Aug 29.


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