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Items: 1 to 20 of 369

1.

Cell-to-cell heterogeneity of EWSR1-FLI1 activity determines proliferation/migration choices in Ewing sarcoma cells.

Franzetti GA, Laud-Duval K, van der Ent W, Brisac A, Irondelle M, Aubert S, Dirksen U, Bouvier C, de Pinieux G, Snaar-Jagalska E, Chavrier P, Delattre O.

Oncogene. 2017 Jan 30. doi: 10.1038/onc.2016.498. [Epub ahead of print]

PMID:
28135250
2.

DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma.

Sheffield NC, Pierron G, Klughammer J, Datlinger P, Schönegger A, Schuster M, Hadler J, Surdez D, Guillemot D, Lapouble E, Freneaux P, Champigneulle J, Bouvier R, Walder D, Ambros IM, Hutter C, Sorz E, Amaral AT, de Álava E, Schallmoser K, Strunk D, Rinner B, Liegl-Atzwanger B, Huppertz B, Leithner A, de Pinieux G, Terrier P, Laurence V, Michon J, Ladenstein R, Holter W, Windhager R, Dirksen U, Ambros PF, Delattre O, Kovar H, Bock C, Tomazou EM.

Nat Med. 2017 Jan 30. doi: 10.1038/nm.4273. [Epub ahead of print]

PMID:
28134926
3.

Rhabdoid component emerging as a subclonal evolution of paediatric glioneuronal tumours.

Bertrand A, Rondenet C, Masliah-Planchon J, Leblond P, de la Fourchardière A, Pissaloux D, Aït-Raïs K, Lequin D, Jouvet A, Freneaux P, Sevestre H, Ranchere-Vince D, Tauziede-Espariat A, Maurage CA, Silva K, Pierron G, Delattre O, Varlet P, Frappaz D, Bourdeaut F.

Neuropathol Appl Neurobiol. 2017 Jan 5. doi: 10.1111/nan.12379. [Epub ahead of print]

PMID:
28054381
4.

Kids Enter the MATCH.

Schleiermacher G, Delattre O.

J Natl Cancer Inst. 2016 Dec 31;109(5). pii: djw305. doi: 10.1093/jnci/djw305. No abstract available.

PMID:
28040695
5.

MicroRNA and gene co-expression networks characterize biological and clinical behavior of rhabdomyosarcomas.

Missiaglia E, Shepherd CJ, Aladowicz E, Olmos D, Selfe J, Pierron G, Delattre O, Walters Z, Shipley J.

Cancer Lett. 2016 Oct 28. pii: S0304-3835(16)30623-1. doi: 10.1016/j.canlet.2016.10.011. [Epub ahead of print]

6.

Feasibility and clinical integration of molecular profiling for target identification in pediatric solid tumors.

Pincez T, Clément N, Lapouble E, Pierron G, Kamal M, Bieche I, Bernard V, Fréneaux P, Michon J, Orbach D, Aerts I, Pacquement H, Bourdeaut F, Jiménez I, Thébaud E, Oudot C, Vérité C, Taque S, Owens C, Doz F, Le Tourneau C, Delattre O, Schleiermacher G.

Pediatr Blood Cancer. 2016 Nov 29. doi: 10.1002/pbc.26365. [Epub ahead of print]

PMID:
27896933
7.

[Over-reduction after distal radius fracture pinning in young active patients: Prevention by multiple mixed pinning].

Delattre O, Greffe G, Stratan L, Duroux F, Donatien J.

Hand Surg Rehabil. 2016 Dec;35S:S89-S94. doi: 10.1016/j.hansur.2016.09.011. French.

PMID:
27890219
8.

High-throughput RNAi screen in Ewing sarcoma cells identifies leucine rich repeats and WD repeat domain containing 1 (LRWD1) as a regulator of EWS-FLI1 driven cell viability.

He T, Surdez D, Rantala JK, Haapa-Paananen S, Ban J, Kauer M, Tomazou E, Fey V, Alonso J, Kovar H, Delattre O, Iljin K.

Gene. 2017 Jan 5;596:137-146. doi: 10.1016/j.gene.2016.10.021.

PMID:
27760381
9.

68Ga-DOTATOC and FDG PET Imaging of Preclinical Neuroblastoma Models.

Provost C, Prignon A, Cazes A, Combaret V, Delattre O, Janoueix-Lerosey I, Montravers F, Talbot JN.

Anticancer Res. 2016 Sep;36(9):4459-66.

PMID:
27630282
10.

Genomic Copy Number Profiling Using Circulating Free Tumor DNA Highlights Heterogeneity in Neuroblastoma.

Chicard M, Boyault S, Colmet Daage L, Richer W, Gentien D, Pierron G, Lapouble E, Bellini A, Clement N, Iacono I, Bréjon S, Carrere M, Reyes C, Hocking T, Bernard V, Peuchmaur M, Corradini N, Faure-Conter C, Coze C, Plantaz D, Defachelles AS, Thebaud E, Gambart M, Millot F, Valteau-Couanet D, Michon J, Puisieux A, Delattre O, Combaret V, Schleiermacher G.

Clin Cancer Res. 2016 Nov 15;22(22):5564-5573. doi: 10.1158/1078-0432.CCR-16-0500.

PMID:
27440268
11.

EWS-FLI1-mediated suppression of the RAS-antagonist Sprouty 1 (SPRY1) confers aggressiveness to Ewing sarcoma.

Cidre-Aranaz F, Grünewald TG, Surdez D, García-García L, Carlos Lázaro J, Kirchner T, González-González L, Sastre A, García-Miguel P, López-Pérez SE, Monzón S, Delattre O, Alonso J.

Oncogene. 2017 Feb 9;36(6):766-776. doi: 10.1038/onc.2016.244.

PMID:
27375017
12.

Cooperation between somatic mutations and germline susceptibility variants in tumorigenesis - a dangerous liaison.

Grünewald TG, Delattre O.

Mol Cell Oncol. 2015 Oct 6;3(3):e1086853. doi: 10.1080/23723556.2015.1086853.

13.

Identification of genetic variants in pharmacokinetic genes associated with Ewing Sarcoma treatment outcome.

Ruiz-Pinto S, Pita G, Patiño-García A, García-Miguel P, Alonso J, Pérez-Martínez A, Sastre A, Gómez-Mariano G, Lissat A, Scotlandi K, Serra M, Ladenstein R, Lapouble E, Pierron G, Kontny U, Picci P, Kovar H, Delattre O, González-Neira A.

Ann Oncol. 2016 Sep;27(9):1788-93. doi: 10.1093/annonc/mdw234.

PMID:
27287205
14.

Combined experience of six independent laboratories attempting to create an Ewing sarcoma mouse model.

Minas TZ, Surdez D, Javaheri T, Tanaka M, Howarth M, Kang HJ, Han J, Han ZY, Sax B, Kream BE, Hong SH, Çelik H, Tirode F, Tuckermann J, Toretsky JA, Kenner L, Kovar H, Lee S, Sweet-Cordero EA, Nakamura T, Moriggl R, Delattre O, Üren A.

Oncotarget. 2016 May 15. doi: 10.18632/oncotarget.9388. [Epub ahead of print]

15.

[Cooperation between a somatic mutation and a genetic susceptibility variant in Ewing sarcoma].

Grünewald TG, Gilardi-Hebenstreit P, Charnay P, Delattre O.

Med Sci (Paris). 2016 Apr;32(4):323-6. doi: 10.1051/medsci/20163204004. French. No abstract available.

PMID:
27137684
16.

LIN7A is a major determinant of cell-polarity defects in breast carcinomas.

Gruel N, Fuhrmann L, Lodillinsky C, Benhamo V, Mariani O, Cédenot A, Arnould L, Macgrogan G, Sastre-Garau X, Chavrier P, Delattre O, Vincent-Salomon A.

Breast Cancer Res. 2016 Feb 17;18(1):23. doi: 10.1186/s13058-016-0680-x.

17.

Segmental Chromosomal Aberrations in Localized Neuroblastoma Can be Detected in Formalin-Fixed Paraffin-Embedded Tissue Samples and Are Associated With Recurrence.

Pinto N, Mayfield JR, Raca G, Applebaum MA, Chlenski A, Sukhanova M, Bagatell R, Irwin MS, Little A, Rawwas J, Gosiengfiao Y, Delattre O, Janoueix-Lerosey I, Lapouble E, Schleiermacher G, Cohn SL.

Pediatr Blood Cancer. 2016 Jun;63(6):1019-23. doi: 10.1002/pbc.25934.

PMID:
26864375
18.

The occurrence of intracranial rhabdoid tumours in mice depends on temporal control of Smarcb1 inactivation.

Han ZY, Richer W, Fréneaux P, Chauvin C, Lucchesi C, Guillemot D, Grison C, Lequin D, Pierron G, Masliah-Planchon J, Nicolas A, Ranchère-Vince D, Varlet P, Puget S, Janoueix-Lerosey I, Ayrault O, Surdez D, Delattre O, Bourdeaut F.

Nat Commun. 2016 Jan 28;7:10421. doi: 10.1038/ncomms10421.

19.

The second European interdisciplinary Ewing sarcoma research summit--A joint effort to deconstructing the multiple layers of a complex disease.

Kovar H, Amatruda J, Brunet E, Burdach S, Cidre-Aranaz F, de Alava E, Dirksen U, van der Ent W, Grohar P, Grünewald TG, Helman L, Houghton P, Iljin K, Korsching E, Ladanyi M, Lawlor E, Lessnick S, Ludwig J, Meltzer P, Metzler M, Mora J, Moriggl R, Nakamura T, Papamarkou T, Radic Sarikas B, Rédini F, Richter GH, Rossig C, Schadler K, Schäfer BW, Scotlandi K, Sheffield NC, Shelat A, Snaar-Jagalska E, Sorensen P, Stegmaier K, Stewart E, Sweet-Cordero A, Szuhai K, Tirado OM, Tirode F, Toretsky J, Tsafou K, Üren A, Zinovyev A, Delattre O.

Oncotarget. 2016 Feb 23;7(8):8613-24. doi: 10.18632/oncotarget.6937. Review.

20.

Lin28B and Let-7 in the Control of Sympathetic Neurogenesis and Neuroblastoma Development.

Hennchen M, Stubbusch J, Abarchan-El Makhfi I, Kramer M, Deller T, Pierre-Eugene C, Janoueix-Lerosey I, Delattre O, Ernsberger U, Schulte JB, Rohrer H.

J Neurosci. 2015 Dec 16;35(50):16531-44. doi: 10.1523/JNEUROSCI.2560-15.2015.

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