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Items: 7


Promoter methylation of argininosuccinate synthetase-1 sensitises lymphomas to arginine deiminase treatment, autophagy and caspase-dependent apoptosis.

Delage B, Luong P, Maharaj L, O'Riain C, Syed N, Crook T, Hatzimichael E, Papoudou-Bai A, Mitchell TJ, Whittaker SJ, Cerio R, Gribben J, Lemoine N, Bomalaski J, Li CF, Joel S, Fitzgibbon J, Chen LT, Szlosarek PW.

Cell Death Dis. 2012 Jul 5;3:e342. doi: 10.1038/cddis.2012.83.


Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly.

Rajendran P, Delage B, Dashwood WM, Yu TW, Wuth B, Williams DE, Ho E, Dashwood RH.

Mol Cancer. 2011 May 30;10:68. doi: 10.1186/1476-4598-10-68.


Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: studies with sulforaphane and garlic organosulfur compounds.

Nian H, Delage B, Ho E, Dashwood RH.

Environ Mol Mutagen. 2009 Apr;50(3):213-21. doi: 10.1002/em.20454. Review.


Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 promoter.

Nian H, Delage B, Pinto JT, Dashwood RH.

Carcinogenesis. 2008 Sep;29(9):1816-24. doi: 10.1093/carcin/bgn165. Epub 2008 Jul 14.


Dietary manipulation of histone structure and function.

Delage B, Dashwood RH.

Annu Rev Nutr. 2008;28:347-66. doi: 10.1146/annurev.nutr.28.061807.155354. Review.


Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis.

Higdon JV, Delage B, Williams DE, Dashwood RH.

Pharmacol Res. 2007 Mar;55(3):224-36. Epub 2007 Jan 25. Review.

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