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Items: 1 to 20 of 635


Instructive Role of the Microenvironment in Preventing Renal Fibrosis.

Matsumoto K, Xavier S, Chen J, Kida Y, Lipphardt M, Ikeda R, Gevertz A, Caviris M, Hatzopoulos AK, Kalajzic I, Dutton J, Ratliff BB, Zhao H, Darzynkiewicz Z, Rose-John S, Goligorsky MS.

Stem Cells Transl Med. 2016 Oct 5. pii: sctm.2016-0095.


Low level phosphorylation of histone H2AX on serine 139 (γH2AX) is not associated with DNA double-strand breaks.

Rybak P, Hoang A, Bujnowicz L, Bernas T, Berniak K, ZarÄ Bski MA, Darzynkiewicz Z, Dobrucki J.

Oncotarget. 2016 Jul 6. doi: 10.18632/oncotarget.10411. [Epub ahead of print]


Epoxyeicosatrienoic Acids Regulate Adipocyte Differentiation of Mouse 3T3 Cells, Via PGC-1α Activation, Which Is Required for HO-1 Expression and Increased Mitochondrial Function.

Waldman M, Bellner L, Vanella L, Schragenheim J, Sodhi K, Singh SP, Lin D, Lakhkar A, Li J, Hochhauser E, Arad M, Darzynkiewicz Z, Kappas A, Abraham NG.

Stem Cells Dev. 2016 Jul 15;25(14):1084-94. doi: 10.1089/scd.2016.0072. Epub 2016 Jun 27.


How Diet Intervention via Modulation of DNA Damage Response through MicroRNAs May Have an Effect on Cancer Prevention and Aging, an in Silico Study.

Carotenuto F, Albertini MC, Coletti D, Vilmercati A, Campanella L, Darzynkiewicz Z, Teodori L.

Int J Mol Sci. 2016 May 19;17(5). pii: E752. doi: 10.3390/ijms17050752.


Assessment of red blood cell distribution width as a prognostic marker in chronic lymphocytic leukemia.

Podhorecka M, Halicka D, Szymczyk A, Macheta A, Chocholska S, Hus M, Darzynkiewicz Z.

Oncotarget. 2016 May 31;7(22):32846-53. doi: 10.18632/oncotarget.9055.


Subnuclear localization, rates and effectiveness of UVC-induced unscheduled DNA synthesis visualized by fluorescence widefield, confocal and super-resolution microscopy.

Pierzyńska-Mach A, Szczurek A, Cella Zanacchi F, Pennacchietti F, Drukała J, Diaspro A, Cremer C, Darzynkiewicz Z, Dobrucki JW.

Cell Cycle. 2016;15(8):1156-67. doi: 10.1080/15384101.2016.1158377.


Gene 33/Mig6 inhibits hexavalent chromium-induced DNA damage and cell transformation in human lung epithelial cells.

Park S, Li C, Zhao H, Darzynkiewicz Z, Xu D.

Oncotarget. 2016 Feb 23;7(8):8916-30. doi: 10.18632/oncotarget.6866.


Hyperactive ERK and persistent mTOR signaling characterize vemurafenib resistance in papillary thyroid cancer cells.

Hanly EK, Tuli NY, Bednarczyk RB, Suriano R, Geliebter J, Moscatello AL, Darzynkiewicz Z, Tiwari RK.

Oncotarget. 2016 Feb 23;7(8):8676-87. doi: 10.18632/oncotarget.6779.


Rapid and simple detection of gero-suppressive agents.

Darzynkiewicz Z.

Oncotarget. 2015 Sep 15;6(27):23050-1. No abstract available.


mTOR inhibitors sensitize thyroid cancer cells to cytotoxic effect of vemurafenib.

Hanly EK, Bednarczyk RB, Tuli NY, Moscatello AL, Halicka HD, Li J, Geliebter J, Darzynkiewicz Z, Tiwari RK.

Oncotarget. 2015 Nov 24;6(37):39702-13. doi: 10.18632/oncotarget.4052.


Effect of different N7 substitution of dinucleotide cap analogs on the hydrolytic susceptibility towards scavenger decapping enzymes (DcpS).

Piecyk K, Darzynkiewicz ZM, Jankowska-Anyszka M, Ferenc-Mrozek A, Stepinski J, Darzynkiewicz E, Bojarska E.

Biochem Biophys Res Commun. 2015 Aug 14;464(1):89-93. doi: 10.1016/j.bbrc.2015.06.001. Epub 2015 Jun 4.


Biguanides and targeted anti-cancer treatments.

Hanly EK, Darzynkiewicz Z, Tiwari RK.

Genes Cancer. 2015 Mar;6(3-4):82-3. No abstract available.

Free PMC Article

Expression of the p12 subunit of human DNA polymerase δ (Pol δ), CDK inhibitor p21(WAF1), Cdt1, cyclin A, PCNA and Ki-67 in relation to DNA replication in individual cells.

Zhao H, Zhang S, Xu D, Lee MY, Zhang Z, Lee EY, Darzynkiewicz Z.

Cell Cycle. 2014;13(22):3529-40. doi: 10.4161/15384101.2014.958910.


Synthesis, properties, and biological activity of boranophosphate analogs of the mRNA cap: versatile tools for manipulation of therapeutically relevant cap-dependent processes.

Kowalska J, Wypijewska del Nogal A, Darzynkiewicz ZM, Buck J, Nicola C, Kuhn AN, Lukaszewicz M, Zuberek J, Strenkowska M, Ziemniak M, Maciejczyk M, Bojarska E, Rhoads RE, Darzynkiewicz E, Sahin U, Jemielity J.

Nucleic Acids Res. 2014;42(16):10245-64. doi: 10.1093/nar/gku757. Epub 2014 Aug 22.


Attenuation of replication stress-induced premature cellular senescence to assess anti-aging modalities.

Zhao H, Darzynkiewicz Z.

Curr Protoc Cytom. 2014 Jul 1;69:9.47.1-9.47.10. doi: 10.1002/0471142956.cy0947s69.


Different rates of DNA replication at early versus late S-phase sections: multiscale modeling of stochastic events related to DNA content/EdU (5-ethynyl-2'deoxyuridine) incorporation distributions.

Li B, Zhao H, Rybak P, Dobrucki JW, Darzynkiewicz Z, Kimmel M.

Cytometry A. 2014 Sep;85(9):785-97. doi: 10.1002/cyto.a.22484. Epub 2014 Jun 3.


Cytotoxic activity of the amphibian ribonucleases onconase and r-amphinase on tumor cells from B cell lymphoproliferative disorders.

Smolewski P, Witkowska M, Zwolinska M, Cebula-Obrzut B, Majchrzak A, Jeske A, Darzynkiewicz Z, Ardelt W, Ardelt B, Robak T.

Int J Oncol. 2014 Jul;45(1):419-25. doi: 10.3892/ijo.2014.2405. Epub 2014 Apr 28.


In search of antiaging modalities: evaluation of mTOR- and ROS/DNA damage-signaling by cytometry.

Darzynkiewicz Z, Zhao H, Halicka HD, Li J, Lee YS, Hsieh TC, Wu JM.

Cytometry A. 2014 May;85(5):386-99. doi: 10.1002/cyto.a.22452. Epub 2014 Feb 22. Review.


Disruption of mutated BRAF signaling modulates thyroid cancer phenotype.

Hanly EK, Rajoria S, Darzynkiewicz Z, Zhao H, Suriano R, Tuli N, George AL, Bednarczyk R, Shin EJ, Geliebter J, Tiwari RK.

BMC Res Notes. 2014 Mar 28;7:187. doi: 10.1186/1756-0500-7-187.

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