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Items: 1 to 20 of 38


Unhealthy smokers: scopes for prophylactic intervention and clinical treatment.

Prasad S, Kaisar MA, Cucullo L.

BMC Neurosci. 2017 Oct 4;18(1):70. doi: 10.1186/s12868-017-0388-6. Review.


Proximate Mediators of Microvascular Dysfunction at the Blood-Brain Barrier: Neuroinflammatory Pathways to Neurodegeneration.

Festoff BW, Sajja RK, Cucullo L.

Biomed Res Int. 2017;2017:1549194. doi: 10.1155/2017/1549194. Epub 2017 Aug 14. Review.


Offsetting the impact of smoking and e-cigarette vaping on the cerebrovascular system and stroke injury: Is Metformin a viable countermeasure?

Kaisar MA, Villalba H, Prasad S, Liles T, Sifat AE, Sajja RK, Abbruscato TJ, Cucullo L.

Redox Biol. 2017 Oct;13:353-362. doi: 10.1016/j.redox.2017.06.006. Epub 2017 Jun 17.


Role of Nrf2 and protective effects of Metformin against tobacco smoke-induced cerebrovascular toxicity.

Prasad S, Sajja RK, Kaisar MA, Park JH, Villalba H, Liles T, Abbruscato T, Cucullo L.

Redox Biol. 2017 Aug;12:58-69. doi: 10.1016/j.redox.2017.02.007. Epub 2017 Feb 12.


New experimental models of the blood-brain barrier for CNS drug discovery.

Kaisar MA, Sajja RK, Prasad S, Abhyankar VV, Liles T, Cucullo L.

Expert Opin Drug Discov. 2017 Jan;12(1):89-103. Epub 2016 Nov 7. Review.


Membrane Transporters and Pharmacological Implications.

Cucullo L, Liles T.

J Pharmacovigil. 2016 Jun;4(3). pii: e155. Epub 2016 Jun 8. No abstract available.


HMGB1 and thrombin mediate the blood-brain barrier dysfunction acting as biomarkers of neuroinflammation and progression to neurodegeneration in Alzheimer's disease.

Festoff BW, Sajja RK, van Dreden P, Cucullo L.

J Neuroinflammation. 2016 Aug 24;13(1):194. doi: 10.1186/s12974-016-0670-z.


A decade of e-cigarettes: Limited research & unresolved safety concerns.

Kaisar MA, Prasad S, Liles T, Cucullo L.

Toxicology. 2016 Jul 15;365:67-75. doi: 10.1016/j.tox.2016.07.020. Epub 2016 Jul 28. Review.


Hyperglycemia exacerbates antiretroviral drug combination induced blood-brain barrier endothelial toxicity.

Prasad S, Sajja RK, Kaisar MA, Cucullo L.

Neurotoxicology. 2016 Sep;56:1-6. doi: 10.1016/j.neuro.2016.06.011. Epub 2016 Jun 23.


Impact of Tobacco Smoking and Type-2 Diabetes Mellitus on Public Health: A Cerebrovascular Perspective.

Prasad S, Cucullo L.

J Pharmacovigil. 2015 Nov;Suppl 2. pii: e003. Epub 2015 Nov 12. No abstract available.


Drugs of abuse and blood-brain barrier endothelial dysfunction: A focus on the role of oxidative stress.

Sajja RK, Rahman S, Cucullo L.

J Cereb Blood Flow Metab. 2016 Mar;36(3):539-54. doi: 10.1177/0271678X15616978. Epub 2015 Nov 17. Review.


Pathobiology of tobacco smoking and neurovascular disorders: untied strings and alternative products.

Naik P, Cucullo L.

Fluids Barriers CNS. 2015 Oct 31;12:25. doi: 10.1186/s12987-015-0022-x. Review.


Protecting the BBB endothelium against cigarette smoke-induced oxidative stress using popular antioxidants: Are they really beneficial?

Kaisar MA, Prasad S, Cucullo L.

Brain Res. 2015 Nov 19;1627:90-100. doi: 10.1016/j.brainres.2015.09.018. Epub 2015 Sep 26.


Impact of cigarette smoke extract and hyperglycemic conditions on blood-brain barrier endothelial cells.

Prasad S, Sajja RK, Park JH, Naik P, Kaisar MA, Cucullo L.

Fluids Barriers CNS. 2015 Jul 24;12:18. doi: 10.1186/s12987-015-0014-x.


OTC Antioxidant Products for the Treatment of Cardiovascular and other Disorders: Popular Myth or Fact?

Kaisar MA, Cucullo L.

J Pharmacovigil. 2015 Apr;3(2). pii: e136. No abstract available.


Altered glycaemia differentially modulates efflux transporter expression and activity in hCMEC/D3 cell line.

Sajja RK, Cucullo L.

Neurosci Lett. 2015 Jun 26;598:59-65. doi: 10.1016/j.neulet.2015.05.015. Epub 2015 May 14.


Altered Nrf2 signaling mediates hypoglycemia-induced blood-brain barrier endothelial dysfunction in vitro.

Sajja RK, Green KN, Cucullo L.

PLoS One. 2015 Mar 25;10(3):e0122358. doi: 10.1371/journal.pone.0122358. eCollection 2015.


Differential Cerebrovascular Toxicity of Various Tobacco Products: A Regulatory Perspective.

Sajja RK, Naik P, Cucullo L.

J Pharmacovigil. 2015;3(1). pii: 1000e130. No abstract available.

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