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Items: 1 to 20 of 35


Venetoclax Is Effective in Small-Cell Lung Cancers with High BCL-2 Expression.

Lochmann TL, Floros KV, Naseri M, Powell KM, Cook W, March RJ, Stein GT, Greninger P, Maves YK, Saunders LR, Dylla SJ, Costa C, Boikos SA, Leverson JD, Souers AJ, Krystal GW, Harada H, Benes CH, Faber AC.

Clin Cancer Res. 2018 Jan 15;24(2):360-369. doi: 10.1158/1078-0432.CCR-17-1606. Epub 2017 Nov 8.


The ZDSD rat: a novel model of diabetic nephropathy.

Peterson RG, Jackson CV, Zimmerman KM.

Am J Transl Res. 2017 Sep 15;9(9):4236-4249. eCollection 2017.


Comparison of Continuous Glucose Monitoring between Dexcom G4 Platinum and HD-XG Systems in Nonhuman Primates (Macaca Fascicularis).

Wang B, Qiao W, Ye W, Wang X, Liu Y, Wang YJ, Xiao YF.

Sci Rep. 2017 Aug 29;7(1):9596. doi: 10.1038/s41598-017-09806-w.


EGFR gene status predicts response and survival benefit in a preclinical gastric cancer trial treating patient‑derived xenografts with cetuximab.

Wang X, Fu R, Hu Y, Du H, Li S, Li Z, Liu Y, Li Q, Zhang L, Ji J.

Oncol Rep. 2017 Oct;38(4):2387-2393. doi: 10.3892/or.2017.5907. Epub 2017 Aug 14.


Identification of Novel Proteins Interacting with Vascular Endothelial Growth Inhibitor 174 in Renal Cell Carcinoma.

Zhao Q, Kun D, Hong B, Deng X, Guo S, Tang X, Yang Y, Gong K, Li Q, Ye L, Jiang WG, Zhang N.

Anticancer Res. 2017 Aug;37(8):4379-4388.


Correlation of disease severity with body weight and high fat diet in the FATZO/Pco mouse.

Droz BA, Sneed BL, Jackson CV, Zimmerman KM, Michael MD, Emmerson PJ, Coskun T, Peterson RG.

PLoS One. 2017 Jun 22;12(6):e0179808. doi: 10.1371/journal.pone.0179808. eCollection 2017.


Glucose dysregulation and response to common anti-diabetic agents in the FATZO/Pco mouse.

Peterson RG, Jackson CV, Zimmerman KM, Alsina-Fernandez J, Michael MD, Emmerson PJ, Coskun T.

PLoS One. 2017 Jun 22;12(6):e0179856. doi: 10.1371/journal.pone.0179856. eCollection 2017.


Drugging the catalytically inactive state of RET kinase in RET-rearranged tumors.

Plenker D, Riedel M, Brägelmann J, Dammert MA, Chauhan R, Knowles PP, Lorenz C, Keul M, Bührmann M, Pagel O, Tischler V, Scheel AH, Schütte D, Song Y, Stark J, Mrugalla F, Alber Y, Richters A, Engel J, Leenders F, Heuckmann JM, Wolf J, Diebold J, Pall G, Peifer M, Aerts M, Gevaert K, Zahedi RP, Buettner R, Shokat KM, McDonald NQ, Kast SM, Gautschi O, Thomas RK, Sos ML.

Sci Transl Med. 2017 Jun 14;9(394). pii: eaah6144. doi: 10.1126/scitranslmed.aah6144.


Intra-tumour molecular heterogeneity of clear cell renal cell carcinoma reveals the diversity of the response to targeted therapies using patient-derived xenograft models.

Hong B, Yang Y, Guo S, Duoerkun S, Deng X, Chen D, Yu S, Qian W, Li Q, Li Q, Gong K, Zhang N.

Oncotarget. 2017 Jul 25;8(30):49839-49850. doi: 10.18632/oncotarget.17765.


The Stearoyl-CoA Desaturase-1 (Desat1) in Drosophila cooperated with Myc to Induce Autophagy and Growth, a Potential New Link to Tumor Survival.

Paiardi C, Mirzoyan Z, Zola S, Parisi F, Vingiani A, Pasini ME, Bellosta P.

Genes (Basel). 2017 Apr 28;8(5). pii: E131. doi: 10.3390/genes8050131.


Long-term blood glucose monitoring with implanted telemetry device in conscious and stress-free cynomolgus monkeys.

Wang B, Sun G, Qiao W, Liu Y, Qiao J, Ye W, Wang H, Wang X, Lindquist R, Wang Y, Xiao YF.

J Endocrinol Invest. 2017 Sep;40(9):967-977. doi: 10.1007/s40618-017-0651-9. Epub 2017 Apr 1.


Experimental animal modeling for immuno-oncology.

Li QX, Feuer G, Ouyang X, An X.

Pharmacol Ther. 2017 May;173:34-46. doi: 10.1016/j.pharmthera.2017.02.002. Epub 2017 Feb 4. Review.


Phenotyping of adipose, liver, and skeletal muscle insulin resistance and response to pioglitazone in spontaneously obese rhesus monkeys.

Shang J, Previs SF, Conarello S, Chng K, Zhu Y, Souza SC, Staup M, Chen Y, Xie D, Zycband E, Schlessinger K, Johnson VP, Arreaza G, Liu F, Levitan D, Wang L, van Heek M, Erion M, Wang Y, Kelley DE.

Am J Physiol Endocrinol Metab. 2017 Apr 1;312(4):E235-E243. doi: 10.1152/ajpendo.00398.2016. Epub 2017 Jan 31.


Identification of apilimod as a first-in-class PIKfyve kinase inhibitor for treatment of B-cell non-Hodgkin lymphoma.

Gayle S, Landrette S, Beeharry N, Conrad C, Hernandez M, Beckett P, Ferguson SM, Mandelkern T, Zheng M, Xu T, Rothberg J, Lichenstein H.

Blood. 2017 Mar 30;129(13):1768-1778. doi: 10.1182/blood-2016-09-736892. Epub 2017 Jan 19.


Characterization of Metabolic Status in Nonhuman Primates with the Intravenous Glucose Tolerance Test.

Staup M, Aoyagi G, Bayless T, Wang Y, Chng K.

J Vis Exp. 2016 Nov 13;(117). doi: 10.3791/52895.


Nuclear Export of Ubiquitinated Proteins Determines the Sensitivity of Colorectal Cancer to Proteasome Inhibitor.

Wu T, Chen W, Zhong Y, Hou X, Fang S, Liu CY, Wang G, Yu T, Huang YY, Ouyang X, Li HQ, Cui L, Yang Y.

Mol Cancer Ther. 2017 Apr;16(4):717-728. doi: 10.1158/1535-7163.MCT-16-0553. Epub 2016 Nov 30.


AC220 and AraC cause differential inhibitory dynamics in patient-derived M5-AML with FLT3-ITD and, thus, ultimately distinct therapeutic outcomes.

An X, Liu J, Wang N, Wang D, Huang L, Zhang L, Cai J, Wery JP, Zhou D, Zhou J, Li QX.

Exp Hematol. 2017 Jan;45:36-44.e2. doi: 10.1016/j.exphem.2016.09.004. Epub 2016 Sep 23.


Cetuximab response in CRC patient-derived xenografts seems predicted by an expression based RAS pathway signature.

Guo S, Chen D, Huang X, Cai J, Wery JP, Li QX.

Oncotarget. 2016 Aug 2;7(31):50575-50581. doi: 10.18632/oncotarget.10499.

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