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Items: 1 to 20 of 135

1.

Therapeutic Hypothermia after In-Hospital Cardiac Arrest in Children.

Moler FW, Silverstein FS, Holubkov R, Slomine BS, Christensen JR, Nadkarni VM, Meert KL, Browning B, Pemberton VL, Page K, Gildea MR, Scholefield BR, Shankaran S, Hutchison JS, Berger JT, Ofori-Amanfo G, Newth CJ, Topjian A, Bennett KS, Koch JD, Pham N, Chanani NK, Pineda JA, Harrison R, Dalton HJ, Alten J, Schleien CL, Goodman DM, Zimmerman JJ, Bhalala US, Schwarz AJ, Porter MB, Shah S, Fink EL, McQuillen P, Wu T, Skellett S, Thomas NJ, Nowak JE, Baines PB, Pappachan J, Mathur M, Lloyd E, van der Jagt EW, Dobyns EL, Meyer MT, Sanders RC Jr, Clark AE, Dean JM; THAPCA Trial Investigators.

N Engl J Med. 2017 Jan 26;376(4):318-329. doi: 10.1056/NEJMoa1610493. Epub 2017 Jan 24.

2.

Association of Delay in Appendectomy With Perforation in Children With Appendicitis.

Meltzer JA, Kunkov S, Chao JH, Tay ET, George JP, Borukhov D, Alerhand S, Harrison PA, Hom J, Crain EF.

Pediatr Emerg Care. 2016 Sep 30. [Epub ahead of print]

PMID:
27749630
3.

Pediatric Out-of-Hospital Cardiac Arrest Characteristics and Their Association With Survival and Neurobehavioral Outcome.

Meert KL, Telford R, Holubkov R, Slomine BS, Christensen JR, Dean JM, Moler FW; Therapeutic Hypothermia after Pediatric Cardiac Arrest (THAPCA) Trial Investigators.

Pediatr Crit Care Med. 2016 Dec;17(12):e543-e550.

PMID:
27679965
4.
5.

Association of RNA Biosignatures With Bacterial Infections in Febrile Infants Aged 60 Days or Younger.

Mahajan P, Kuppermann N, Mejias A, Suarez N, Chaussabel D, Casper TC, Smith B, Alpern ER, Anders J, Atabaki SM, Bennett JE, Blumberg S, Bonsu B, Borgialli D, Brayer A, Browne L, Cohen DM, Crain EF, Cruz AT, Dayan PS, Gattu R, Greenberg R, Hoyle JD Jr, Jaffe DM, Levine DA, Lillis K, Linakis JG, Muenzer J, Nigrovic LE, Powell EC, Rogers AJ, Roosevelt G, Ruddy RM, Saunders M, Tunik MG, Tzimenatos L, Vitale M, Dean JM, Ramilo O; Pediatric Emergency Care Applied Research Network (PECARN).

JAMA. 2016 Aug 23-30;316(8):846-57. doi: 10.1001/jama.2016.9207. Erratum in: JAMA. 2016 Nov 8;316(18):1924.

6.

Novel phenylalanine derived diamides as Factor XIa inhibitors.

Smith LM 2nd, Orwat MJ, Hu Z, Han W, Wang C, Rossi KA, Gilligan PJ, Pabbisetty KB, Osuna H, Corte JR, Rendina AR, Luettgen JM, Wong PC, Narayanan R, Harper TW, Bozarth JM, Crain EJ, Wei A, Ramamurthy V, Morin PE, Xin B, Zheng J, Seiffert DA, Quan ML, Lam PYS, Wexler RR, Pinto DJP.

Bioorg Med Chem Lett. 2016 Jan 15;26(2):472-478. doi: 10.1016/j.bmcl.2015.11.089. Epub 2015 Nov 26.

PMID:
26704266
7.

The P2Y1 receptor antagonist MRS2500 prevents carotid artery thrombosis in cynomolgus monkeys.

Wong PC, Watson C, Crain EJ.

J Thromb Thrombolysis. 2016 Apr;41(3):514-21. doi: 10.1007/s11239-015-1302-7.

PMID:
26660522
8.

Development, Evaluation and Implementation of Chief Complaint Groupings to Activate Data Collection: A Multi-Center Study of Clinical Decision Support for Children with Head Trauma.

Deakyne SJ, Bajaj L, Hoffman J, Alessandrini E, Ballard DW, Norris R, Tzimenatos L, Swietlik M, Tham E, Grundmeier RW, Kuppermann N, Dayan PS; Pediatric Emergency Care Applied Research Network (PECARN).

Appl Clin Inform. 2015 Aug 19;6(3):521-35. doi: 10.4338/ACI-2015-02-RA-0019. eCollection 2015.

9.

Microaggressions, Feelings of Difference, and Resilience Among Adopted Children with Sexual Minority Parents.

Farr RH, Crain EE, Oakley MK, Cashen KK, Garber KJ.

J Youth Adolesc. 2016 Jan;45(1):85-104. doi: 10.1007/s10964-015-0353-6. Epub 2015 Sep 15.

PMID:
26374241
10.

Near misses and unsafe conditions reported in a Pediatric Emergency Research Network.

Ruddy RM, Chamberlain JM, Mahajan PV, Funai T, O'Connell KJ, Blumberg S, Lichenstein R, Gramse HL, Shaw KN; Pediatric Emergency Care Applied Research Network.

BMJ Open. 2015 Sep 2;5(9):e007541. doi: 10.1136/bmjopen-2014-007541.

11.

In vitro, antithrombotic and bleeding time studies of BMS-654457, a small-molecule, reversible and direct inhibitor of factor XIa.

Wong PC, Quan ML, Watson CA, Crain EJ, Harpel MR, Rendina AR, Luettgen JM, Wexler RR, Schumacher WA, Seiffert DA.

J Thromb Thrombolysis. 2015 Nov;40(4):416-23. doi: 10.1007/s11239-015-1258-7.

PMID:
26249722
12.

Discovery of a Potent Parenterally Administered Factor XIa Inhibitor with Hydroxyquinolin-2(1H)-one as the P2' Moiety.

Hu Z, Wong PC, Gilligan PJ, Han W, Pabbisetty KB, Bozarth JM, Crain EJ, Harper T, Luettgen JM, Myers JE Jr, Ramamurthy V, Rossi KA, Sheriff S, Watson CA, Wei A, Zheng JJ, Seiffert DA, Wexler RR, Quan ML.

ACS Med Chem Lett. 2015 Apr 8;6(5):590-5. doi: 10.1021/acsmedchemlett.5b00066. eCollection 2015 May 14.

13.

RNA transcriptional biosignature analysis for identifying febrile infants with serious bacterial infections in the emergency department: a feasibility study.

Mahajan P, Kuppermann N, Suarez N, Mejias A, Casper C, Dean JM, Ramilo O; Febrile Infant Working Group for the Pediatric Emergency Care Applied Research Network (PECARN).

Pediatr Emerg Care. 2015 Jan;31(1):1-5. doi: 10.1097/PEC.0000000000000324.

14.

Discovery of 4-aryl-7-hydroxyindoline-based P2Y1 antagonists as novel antiplatelet agents.

Yang W, Wang Y, Lai A, Qiao JX, Wang TC, Hua J, Price LA, Shen H, Chen XQ, Wong P, Crain E, Watson C, Huang CS, Seiffert DA, Rehfuss R, Wexler RR, Lam PY.

J Med Chem. 2014 Jul 24;57(14):6150-64. doi: 10.1021/jm5006226. Epub 2014 Jul 7.

PMID:
24931384
15.

Lorazepam vs diazepam for pediatric status epilepticus: a randomized clinical trial.

Chamberlain JM, Okada P, Holsti M, Mahajan P, Brown KM, Vance C, Gonzalez V, Lichenstein R, Stanley R, Brousseau DC, Grubenhoff J, Zemek R, Johnson DW, Clemons TE, Baren J; Pediatric Emergency Care Applied Research Network (PECARN).

JAMA. 2014 Apr 23-30;311(16):1652-60. doi: 10.1001/jama.2014.2625.

PMID:
24756515
16.

Pediatrics and the lure of technology.

Crain EF.

Acad Pediatr. 2014 Jan-Feb;14(1):4-7. doi: 10.1016/j.acap.2013.09.004. No abstract available.

PMID:
24369862
17.

Predictors of severe H1N1 infection in children presenting within Pediatric Emergency Research Networks (PERN): retrospective case-control study.

Dalziel SR, Thompson JM, Macias CG, Fernandes RM, Johnson DW, Waisman Y, Cheng N, Acworth J, Chamberlain JM, Osmond MH, Plint A, Valerio P, Black KJ, Fitzpatrick E, Newton AS, Kuppermann N, Klassen TP; Pediatric Emergency Research Networks H1N1 Working Group.

BMJ. 2013 Aug 12;347:f4836. doi: 10.1136/bmj.f4836.

18.

Informing the design of clinical decision support services for evaluation of children with minor blunt head trauma in the emergency department: a sociotechnical analysis.

Sheehan B, Nigrovic LE, Dayan PS, Kuppermann N, Ballard DW, Alessandrini E, Bajaj L, Goldberg H, Hoffman J, Offerman SR, Mark DG, Swietlik M, Tham E, Tzimenatos L, Vinson DR, Jones GS, Bakken S; Pediatric Emergency Care Applied Research Network (PECARN).

J Biomed Inform. 2013 Oct;46(5):905-13. doi: 10.1016/j.jbi.2013.07.005. Epub 2013 Jul 24.

19.

Calling 911! What role does the pediatrician play?

Grossman D, Kunkov S, Kaplan C, Crain EF.

Pediatr Emerg Care. 2013 Jun;29(6):726-8. doi: 10.1097/PEC.0b013e318294dd98.

PMID:
23714760
20.

Discovery of diarylurea P2Y(1) antagonists with improved aqueous solubility.

Wang TC, Qiao JX, Clark CG, Jua J, Price LA, Wu Q, Chang M, Zheng J, Huang CS, Everlof G, Schumacher WA, Wong PC, Seiffert DA, Stewart AB, Bostwick JS, Crain EJ, Watson CA, Rehfuss R, Wexler RR, Lam PY.

Bioorg Med Chem Lett. 2013 Jun 1;23(11):3239-43. doi: 10.1016/j.bmcl.2013.03.125. Epub 2013 Apr 6.

PMID:
23602442

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