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Items: 1 to 20 of 265

1.

Chemically induced proximity in biology and medicine.

Stanton BZ, Chory EJ, Crabtree GR.

Science. 2018 Mar 9;359(6380). pii: eaao5902. doi: 10.1126/science.aao5902. Review.

PMID:
29590011
2.

Rapid chromatin repression by Aire provides precise control of immune tolerance.

Koh AS, Miller EL, Buenrostro JD, Moskowitz DM, Wang J, Greenleaf WJ, Chang HY, Crabtree GR.

Nat Immunol. 2018 Feb;19(2):162-172. doi: 10.1038/s41590-017-0032-8. Epub 2018 Jan 15.

PMID:
29335648
3.

Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers.

Hodges HC, Stanton BZ, Cermakova K, Chang CY, Miller EL, Kirkland JG, Ku WL, Veverka V, Zhao K, Crabtree GR.

Nat Struct Mol Biol. 2018 Jan;25(1):61-72. doi: 10.1038/s41594-017-0007-3. Epub 2017 Dec 11.

4.

Rapid and reversible epigenome editing by endogenous chromatin regulators.

Braun SMG, Kirkland JG, Chory EJ, Husmann D, Calarco JP, Crabtree GR.

Nat Commun. 2017 Sep 15;8(1):560. doi: 10.1038/s41467-017-00644-y.

5.

DNA binding drives the association of BRG1/hBRM bromodomains with nucleosomes.

Morrison EA, Sanchez JC, Ronan JL, Farrell DP, Varzavand K, Johnson JK, Gu BX, Crabtree GR, Musselman CA.

Nat Commun. 2017 Jul 14;8:16080. doi: 10.1038/ncomms16080.

6.

Tethering of Lsh at the Oct4 locus promotes gene repression associated with epigenetic changes.

Ren J, Hathaway NA, Crabtree GR, Muegge K.

Epigenetics. 2018;13(2):173-181. doi: 10.1080/15592294.2017.1338234. Epub 2018 Feb 6.

PMID:
28621576
7.

Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits.

Platt RJ, Zhou Y, Slaymaker IM, Shetty AS, Weisbach NR, Kim JA, Sharma J, Desai M, Sood S, Kempton HR, Crabtree GR, Feng G, Zhang F.

Cell Rep. 2017 Apr 11;19(2):335-350. doi: 10.1016/j.celrep.2017.03.052.

8.

A General Non-Radioactive ATPase Assay for Chromatin Remodeling Complexes.

Stanton BZ, Hodges C, Crabtree GR, Zhao K.

Curr Protoc Chem Biol. 2017 Mar 2;9(1):1-10. doi: 10.1002/cpch.16.

9.

TOP2 synergizes with BAF chromatin remodeling for both resolution and formation of facultative heterochromatin.

Miller EL, Hargreaves DC, Kadoch C, Chang CY, Calarco JP, Hodges C, Buenrostro JD, Cui K, Greenleaf WJ, Zhao K, Crabtree GR.

Nat Struct Mol Biol. 2017 Apr;24(4):344-352. doi: 10.1038/nsmb.3384. Epub 2017 Feb 27.

10.

Dynamics of BAF-Polycomb complex opposition on heterochromatin in normal and oncogenic states.

Kadoch C, Williams RT, Calarco JP, Miller EL, Weber CM, Braun SM, Pulice JL, Chory EJ, Crabtree GR.

Nat Genet. 2017 Feb;49(2):213-222. doi: 10.1038/ng.3734. Epub 2016 Dec 12.

11.

Smarca4 ATPase mutations disrupt direct eviction of PRC1 from chromatin.

Stanton BZ, Hodges C, Calarco JP, Braun SM, Ku WL, Kadoch C, Zhao K, Crabtree GR.

Nat Genet. 2017 Feb;49(2):282-288. doi: 10.1038/ng.3735. Epub 2016 Dec 12.

12.

The BAF45a/PHF10 subunit of SWI/SNF-like chromatin remodeling complexes is essential for hematopoietic stem cell maintenance.

Krasteva V, Crabtree GR, Lessard JA.

Exp Hematol. 2017 Apr;48:58-71.e15. doi: 10.1016/j.exphem.2016.11.008. Epub 2016 Dec 5.

PMID:
27931852
13.

The Many Roles of BAF (mSWI/SNF) and PBAF Complexes in Cancer.

Hodges C, Kirkland JG, Crabtree GR.

Cold Spring Harb Perspect Med. 2016 Aug 1;6(8). pii: a026930. doi: 10.1101/cshperspect.a026930. Review.

14.

Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics.

Kadoch C, Crabtree GR.

Sci Adv. 2015 Jun 12;1(5):e1500447. doi: 10.1126/sciadv.1500447. eCollection 2015 Jun. Review.

15.

Generation of BAF53b-Cre transgenic mice with pan-neuronal Cre activities.

Zhan X, Cao M, Yoo AS, Zhang Z, Chen L, Crabtree GR, Wu JI.

Genesis. 2015 Jul;53(7):440-8. doi: 10.1002/dvg.22866. Epub 2015 Jun 23.

16.

The role of BAF (mSWI/SNF) complexes in mammalian neural development.

Son EY, Crabtree GR.

Am J Med Genet C Semin Med Genet. 2014 Sep;166C(3):333-49. doi: 10.1002/ajmg.c.31416. Epub 2014 Sep 5.

17.

Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance.

Buscarlet M, Krasteva V, Ho L, Simon C, H├ębert J, Wilhelm B, Crabtree GR, Sauvageau G, Thibault P, Lessard JA.

Blood. 2014 Mar 13;123(11):1720-8. doi: 10.1182/blood-2013-02-483495. Epub 2014 Jan 29.

18.

Murine esBAF chromatin remodeling complex subunits BAF250a and Brg1 are necessary to maintain and reprogram pluripotency-specific replication timing of select replication domains.

Takebayashi S, Lei I, Ryba T, Sasaki T, Dileep V, Battaglia D, Gao X, Fang P, Fan Y, Esteban MA, Tang J, Crabtree GR, Wang Z, Gilbert DM.

Epigenetics Chromatin. 2013 Dec 13;6(1):42. doi: 10.1186/1756-8935-6-42.

19.

Creating a neural specific chromatin landscape by npBAF and nBAF complexes.

Staahl BT, Crabtree GR.

Curr Opin Neurobiol. 2013 Dec;23(6):903-13. doi: 10.1016/j.conb.2013.09.003. Epub 2013 Oct 1. Review.

20.

Reprogramming human fibroblasts to neurons by recapitulating an essential microRNA-chromatin switch.

Tang J, Yoo AS, Crabtree GR.

Curr Opin Genet Dev. 2013 Oct;23(5):591-8. doi: 10.1016/j.gde.2013.07.001.

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