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Items: 1 to 20 of 45

1.

Recent advances in understanding the complexities of metastasis.

Chitty JL, Filipe EC, Lucas MC, Herrmann D, Cox TR, Timpson P.

Version 2. F1000Res. 2018 Aug 1 [revised 2018 Jan 1];7. pii: F1000 Faculty Rev-1169. doi: 10.12688/f1000research.15064.2. eCollection 2018. Review.

2.

Cancer cells' ability to mechanically adjust to extracellular matrix stiffness correlates with their invasive potential.

Wullkopf L, West AV, Leijnse N, Cox TR, Madsen CD, Oddershede LB, Erler JT.

Mol Biol Cell. 2018 Oct 1;29(20):2378-2385. doi: 10.1091/mbc.E18-05-0319. Epub 2018 Aug 9.

PMID:
30091653
3.

Tumor endothelial marker 8 promotes cancer progression and metastasis.

Høye AM, Tolstrup SD, Horton ER, Nicolau M, Frost H, Woo JH, Mauldin JP, Frankel AE, Cox TR, Erler JT.

Oncotarget. 2018 Jul 10;9(53):30173-30188. doi: 10.18632/oncotarget.25734. eCollection 2018 Jul 10.

4.

Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer.

Cazet AS, Hui MN, Elsworth BL, Wu SZ, Roden D, Chan CL, Skhinas JN, Collot R, Yang J, Harvey K, Johan MZ, Cooper C, Nair R, Herrmann D, McFarland A, Deng N, Ruiz-Borrego M, Rojo F, Trigo JM, Bezares S, Caballero R, Lim E, Timpson P, O'Toole S, Watkins DN, Cox TR, Samuel MS, Martín M, Swarbrick A.

Nat Commun. 2018 Jul 24;9(1):2897. doi: 10.1038/s41467-018-05220-6.

5.

Removing physiological motion from intravital and clinical functional imaging data.

Warren SC, Nobis M, Magenau A, Mohammed YH, Herrmann D, Moran I, Vennin C, Conway JR, Mélénec P, Cox TR, Wang Y, Morton JP, Welch HC, Strathdee D, Anderson KI, Phan TG, Roberts MS, Timpson P.

Elife. 2018 Jul 9;7. pii: e35800. doi: 10.7554/eLife.35800.

6.

Charting the unexplored extracellular matrix in cancer.

Filipe EC, Chitty JL, Cox TR.

Int J Exp Pathol. 2018 Apr;99(2):58-76. doi: 10.1111/iep.12269. Epub 2018 Apr 19. Review.

PMID:
29671911
7.

The extracellular matrix as a key regulator of intracellular signalling networks.

Hastings JF, Skhinas JN, Fey D, Croucher DR, Cox TR.

Br J Pharmacol. 2018 Mar 6. doi: 10.1111/bph.14195. [Epub ahead of print] Review.

PMID:
29510460
8.

Shedding new light on RhoA signalling as a drug target in vivo using a novel RhoA-FRET biosensor mouse.

Nobis M, Herrmann D, Warren SC, Strathdee D, Cox TR, Anderson KI, Timpson P.

Small GTPases. 2018 Mar 21:1-8. doi: 10.1080/21541248.2018.1438024. [Epub ahead of print]

PMID:
29457531
9.

Reshaping the Tumor Stroma for Treatment of Pancreatic Cancer.

Vennin C, Murphy KJ, Morton JP, Cox TR, Pajic M, Timpson P.

Gastroenterology. 2018 Mar;154(4):820-838. doi: 10.1053/j.gastro.2017.11.280. Epub 2017 Dec 26. Review.

PMID:
29287624
10.

Three-dimensional organotypic matrices from alternative collagen sources as pre-clinical models for cell biology.

Conway JRW, Vennin C, Cazet AS, Herrmann D, Murphy KJ, Warren SC, Wullkopf L, Boulghourjian A, Zaratzian A, Da Silva AM, Pajic M, Morton JP, Cox TR, Timpson P.

Sci Rep. 2017 Dec 4;7(1):16887. doi: 10.1038/s41598-017-17177-5.

11.

Proteomic Characterization of Caenorhabditis elegans Larval Development.

Xia T, Horton ER, Salcini AE, Pocock R, Cox TR, Erler JT.

Proteomics. 2018 Jan;18(2). doi: 10.1002/pmic.201700238. Epub 2017 Dec 27.

PMID:
29178193
12.

The interplay between extracellular matrix remodelling and kinase signalling in cancer progression and metastasis.

Skhinas JN, Cox TR.

Cell Adh Migr. 2017 Dec 29:1-9. doi: 10.1080/19336918.2017.1405208. [Epub ahead of print]

PMID:
29168660
13.

Transient targeting of the pancreatic cancer stroma as a 'fine-tuned' anti-tumor and anti-metastatic therapy.

Vennin C, Cox TR, Pajic M, Timpson P.

Oncotarget. 2017 Oct 3;8(49):84635-84636. doi: 10.18632/oncotarget.21468. eCollection 2017 Oct 17. No abstract available.

14.

Established Models and New Paradigms for Hypoxia-Driven Cancer-Associated Bone Disease.

Cox TR, Erler JT, Rumney RMH.

Calcif Tissue Int. 2018 Feb;102(2):163-173. doi: 10.1007/s00223-017-0352-6. Epub 2017 Nov 2. Review.

15.

Tailored first-line and second-line CDK4-targeting treatment combinations in mouse models of pancreatic cancer.

Chou A, Froio D, Nagrial AM, Parkin A, Murphy KJ, Chin VT, Wohl D, Steinmann A, Stark R, Drury A, Walters SN, Vennin C, Burgess A, Pinese M, Chantrill LA, Cowley MJ, Molloy TJ; Australian Pancreatic Cancer Genome Initiative (APGI), Waddell N, Johns A, Grimmond SM, Chang DK, Biankin AV, Sansom OJ, Morton JP, Grey ST, Cox TR, Turchini J, Samra J, Clarke SJ, Timpson P, Gill AJ, Pajic M.

Gut. 2018 Dec;67(12):2142-2155. doi: 10.1136/gutjnl-2017-315144. Epub 2017 Oct 28.

16.

Dynamic Rearrangement of Cell States Detected by Systematic Screening of Sequential Anticancer Treatments.

Koplev S, Longden J, Ferkinghoff-Borg J, Blicher Bjerregård M, Cox TR, Erler JT, Pedersen JT, Voellmy F, Sommer MOA, Linding R.

Cell Rep. 2017 Sep 19;20(12):2784-2791. doi: 10.1016/j.celrep.2017.08.095.

17.

Fibrosis and Cancer: Partners in Crime or Opposing Forces?

Cox TR, Erler JT.

Trends Cancer. 2016 Jun;2(6):279-282. doi: 10.1016/j.trecan.2016.05.004. Epub 2016 May 30.

PMID:
28741525
18.

ISDoT: in situ decellularization of tissues for high-resolution imaging and proteomic analysis of native extracellular matrix.

Mayorca-Guiliani AE, Madsen CD, Cox TR, Horton ER, Venning FA, Erler JT.

Nat Med. 2017 Jul;23(7):890-898. doi: 10.1038/nm.4352. Epub 2017 Jun 12.

PMID:
28604702
19.

Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis.

Vennin C, Chin VT, Warren SC, Lucas MC, Herrmann D, Magenau A, Melenec P, Walters SN, Del Monte-Nieto G, Conway JR, Nobis M, Allam AH, McCloy RA, Currey N, Pinese M, Boulghourjian A, Zaratzian A, Adam AA, Heu C, Nagrial AM, Chou A, Steinmann A, Drury A, Froio D, Giry-Laterriere M, Harris NL, Phan T, Jain R, Weninger W, McGhee EJ, Whan R, Johns AL, Samra JS, Chantrill L, Gill AJ, Kohonen-Corish M, Harvey RP, Biankin AV; Australian Pancreatic Cancer Genome Initiative (APGI), Evans TR, Anderson KI, Grey ST, Ormandy CJ, Gallego-Ortega D, Wang Y, Samuel MS, Sansom OJ, Burgess A, Cox TR, Morton JP, Pajic M, Timpson P.

Sci Transl Med. 2017 Apr 5;9(384). pii: eaai8504. doi: 10.1126/scitranslmed.aai8504.

20.

Pre-metastatic niches: organ-specific homes for metastases.

Peinado H, Zhang H, Matei IR, Costa-Silva B, Hoshino A, Rodrigues G, Psaila B, Kaplan RN, Bromberg JF, Kang Y, Bissell MJ, Cox TR, Giaccia AJ, Erler JT, Hiratsuka S, Ghajar CM, Lyden D.

Nat Rev Cancer. 2017 May;17(5):302-317. doi: 10.1038/nrc.2017.6. Epub 2017 Mar 17. Review.

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