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Acute In Vivo Analysis of ATP Release in Rat Kidneys in Response to Changes of Renal Perfusion Pressure.

Palygin O, Evans LC, Cowley AW Jr, Staruschenko A.

J Am Heart Assoc. 2017 Sep 12;6(9). pii: e006658. doi: 10.1161/JAHA.117.006658.


Inhibition of Mammalian Target of Rapamycin Complex 1 Attenuates Salt-Induced Hypertension and Kidney Injury in Dahl Salt-Sensitive Rats.

Kumar V, Wollner C, Kurth T, Bukowy JD, Cowley AW Jr.

Hypertension. 2017 Oct;70(4):813-821. doi: 10.1161/HYPERTENSIONAHA.117.09456. Epub 2017 Aug 21.


MicroRNA-21 regulates peroxisome proliferator-activated receptor alpha, a molecular mechanism of cardiac pathology in Cardiorenal Syndrome Type 4.

Chuppa S, Liang M, Liu P, Liu Y, Casati MC, Cowley AW, Patullo L, Kriegel AJ.

Kidney Int. 2017 Jul 28. pii: S0085-2538(17)30354-X. doi: 10.1016/j.kint.2017.05.014. [Epub ahead of print]


How can precision medicine be applied to temporomandibular disorders and its comorbidities?

Wilentz JB, Cowley AW Jr.

Mol Pain. 2017 Jan-Dec;13:1744806917710094. doi: 10.1177/1744806917710094.


Increased Perfusion Pressure Drives Renal T-Cell Infiltration in the Dahl Salt-Sensitive Rat.

Evans LC, Petrova G, Kurth T, Yang C, Bukowy JD, Mattson DL, Cowley AW Jr.

Hypertension. 2017 Sep;70(3):543-551. doi: 10.1161/HYPERTENSIONAHA.117.09208. Epub 2017 Jul 10.


Renal Delivery of Anti-microRNA Oligonucleotides in Rats.

Usa KS, Liu Y, Kurth T, Kriegel AJ, Mattson DL, Cowley AW Jr, Liang M.

Methods Mol Biol. 2017;1527:409-419. doi: 10.1007/978-1-4939-6625-7_31.


Breaking the Cycle: Estrous Variation Does Not Require Increased Sample Size in the Study of Female Rats.

Dayton A, Exner EC, Bukowy JD, Stodola TJ, Kurth T, Skelton M, Greene AS, Cowley AW Jr.

Hypertension. 2016 Nov;68(5):1139-1144. Epub 2016 Sep 26.


Role of Nox4 and p67phox subunit of Nox2 in ROS production in response to increased tubular flow in the mTAL of Dahl salt-sensitive rats.

Zheleznova NN, Yang C, Cowley AW Jr.

Am J Physiol Renal Physiol. 2016 Aug 1;311(2):F450-8. doi: 10.1152/ajprenal.00187.2016. Epub 2016 Jun 8.


p66Shc regulates renal vascular tone in hypertension-induced nephropathy.

Miller B, Palygin O, Rufanova VA, Chong A, Lazar J, Jacob HJ, Mattson D, Roman RJ, Williams JM, Cowley AW Jr, Geurts AM, Staruschenko A, Imig JD, Sorokin A.

J Clin Invest. 2016 Jul 1;126(7):2533-46. doi: 10.1172/JCI75079. Epub 2016 Jun 6.


Introduction to the American Heart Association's Hypertension Strategically Focused Research Network.

Muntner P, Becker RC, Calhoun D, Chen D, Cowley AW Jr, Flynn JT, Grobe JL, Kidambi S, Kotchen TA, Lackland DT, Leslie KK, Li Y, Liang M, Lloyd A, Mattson DL, Mendizabal B, Mitsnefes M, Nair A, Pierce GL, Pollock JS, Safford MM, Santillan MK, Sigmund CD, Thomas SJ, Urbina EM.

Hypertension. 2016 Apr;67(4):674-80. doi: 10.1161/HYPERTENSIONAHA.115.06433. Epub 2016 Feb 22. Review. No abstract available.


Ushering Hypertension Into a New Era of Precision Medicine.

Kotchen TA, Cowley AW Jr, Liang M.

JAMA. 2016 Jan 26;315(4):343-4. doi: 10.1001/jama.2015.18359. No abstract available.


Evidence of the Importance of Nox4 in Production of Hypertension in Dahl Salt-Sensitive Rats.

Cowley AW Jr, Yang C, Zheleznova NN, Staruschenko A, Kurth T, Rein L, Kumar V, Sadovnikov K, Dayton A, Hoffman M, Ryan RP, Skelton MM, Salehpour F, Ranji M, Geurts A.

Hypertension. 2016 Feb;67(2):440-50. doi: 10.1161/HYPERTENSIONAHA.115.06280. Epub 2015 Dec 7.


Pappa2 is linked to salt-sensitive hypertension in Dahl S rats.

Cowley AW Jr, Yang C, Kumar V, Lazar J, Jacob H, Geurts AM, Liu P, Dayton A, Kurth T, Liang M.

Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3.


Use of Enzymatic Biosensors to Quantify Endogenous ATP or H2O2 in the Kidney.

Palygin O, Levchenko V, Evans LC, Blass G, Cowley AW Jr, Staruschenko A.

J Vis Exp. 2015 Oct 12;(104). doi: 10.3791/53059.


Endogenous microRNAs in human microvascular endothelial cells regulate mRNAs encoded by hypertension-related genes.

Kriegel AJ, Baker MA, Liu Y, Liu P, Cowley AW Jr, Liang M.

Hypertension. 2015 Oct;66(4):793-9. doi: 10.1161/HYPERTENSIONAHA.115.05645. Epub 2015 Aug 17.


Antithrombin III/SerpinC1 insufficiency exacerbates renal ischemia/reperfusion injury.

Wang F, Zhang G, Lu Z, Geurts AM, Usa K, Jacob HJ, Cowley AW, Wang N, Liang M.

Kidney Int. 2015 Oct;88(4):796-803. doi: 10.1038/ki.2015.176. Epub 2015 Jun 24.


deGPS is a powerful tool for detecting differential expression in RNA-sequencing studies.

Chu C, Fang Z, Hua X, Yang Y, Chen E, Cowley AW Jr, Liang M, Liu P, Lu Y.

BMC Genomics. 2015 Jun 13;16:455. doi: 10.1186/s12864-015-1676-0.


Effects of p67phox on the mitochondrial oxidative state in the kidney of Dahl salt-sensitive rats: optical fluorescence 3-D cryoimaging.

Salehpour F, Ghanian Z, Yang C, Zheleznova NN, Kurth T, Dash RK, Cowley AW Jr, Ranji M.

Am J Physiol Renal Physiol. 2015 Aug 15;309(4):F377-82. doi: 10.1152/ajprenal.00098.2015. Epub 2015 Jun 10.


Genetic, epigenetic, and mechanistic studies of temporomandibular disorders and overlapping pain conditions.

Munzenmaier DH, Wilentz J, Cowley AW Jr.

Mol Pain. 2014 Dec 15;10:72. doi: 10.1186/1744-8069-10-72.


Null mutation of the nicotinamide adenine dinucleotide phosphate-oxidase subunit p67phox protects the Dahl-S rat from salt-induced reductions in medullary blood flow and glomerular filtration rate.

Evans LC, Ryan RP, Broadway E, Skelton MM, Kurth T, Cowley AW Jr.

Hypertension. 2015 Mar;65(3):561-8. doi: 10.1161/HYPERTENSIONAHA.114.04468. Epub 2014 Dec 8.

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