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Fit-for-purpose biomarker immunoassay qualification and validation: three case studies.

Cowan K, Gao X, Parab V, Nguy T, Wu L, Arron JR, Townsend M, Wallin J, Cheu M, Morimoto A, Wakshull E.

Bioanalysis. 2016 Oct 7.


Top 10 research priorities for eating disorders.

van Furth EF, van der Meer A, Cowan K.

Lancet Psychiatry. 2016 Aug;3(8):706-7. doi: 10.1016/S2215-0366(16)30147-X. No abstract available.


Implementing fit-for-purpose biomarker assay approaches: a bioanalytical perspective.

Cowan KJ.

Bioanalysis. 2016 Jun;8(12):1221-3. doi: 10.4155/bio-2016-0070. No abstract available.


Preclinical pharmacokinetics, pharmacodynamics, tissue distribution, and tumor penetration of anti-PD-L1 monoclonal antibody, an immune checkpoint inhibitor.

Deng R, Bumbaca D, Pastuskovas CV, Boswell CA, West D, Cowan KJ, Chiu H, McBride J, Johnson C, Xin Y, Koeppen H, Leabman M, Iyer S.

MAbs. 2016;8(3):593-603. doi: 10.1080/19420862.2015.1136043.


Top ten research priorities for spinal cord injury: the methodology and results of a British priority setting partnership.

van Middendorp JJ, Allison HC, Ahuja S, Bracher D, Dyson C, Fairbank J, Gall A, Glover A, Gray L, Masri WE, Uttridge A, Cowan K.

Spinal Cord. 2016 May;54(5):341-6. doi: 10.1038/sc.2015.199.


Dementia priority setting partnership with the James Lind Alliance: using patient and public involvement and the evidence base to inform the research agenda.

Kelly S, Lafortune L, Hart N, Cowan K, Fenton M, Brayne C; Dementia Priority Setting Partnership..

Age Ageing. 2015 Nov;44(6):985-93. doi: 10.1093/ageing/afv143.


Recommendations for Use and Fit-for-Purpose Validation of Biomarker Multiplex Ligand Binding Assays in Drug Development.

Jani D, Allinson J, Berisha F, Cowan KJ, Devanarayan V, Gleason C, Jeromin A, Keller S, Khan MU, Nowatzke B, Rhyne P, Stephen L.

AAPS J. 2016 Jan;18(1):1-14. doi: 10.1208/s12248-015-9820-y. Review.


Aromatase inhibitors versus tamoxifen in early breast cancer: patient-level meta-analysis of the randomised trials.

Early Breast Cancer Trialists' Collaborative Group (EBCTCG)., Dowsett M, Forbes JF, Bradley R, Ingle J, Aihara T, Bliss J, Boccardo F, Coates A, Coombes RC, Cuzick J, Dubsky P, Gnant M, Kaufmann M, Kilburn L, Perrone F, Rea D, Th├╝rlimann B, van de Velde C, Pan H, Peto R, Davies C, Gray R.

Lancet. 2015 Oct 3;386(10001):1341-52. doi: 10.1016/S0140-6736(15)61074-1.


Adjuvant bisphosphonate treatment in early breast cancer: meta-analyses of individual patient data from randomised trials.

Early Breast Cancer Trialists' Collaborative Group (EBCTCG)., Coleman R, Powles T, Paterson A, Gnant M, Anderson S, Diel I, Gralow J, von Minckwitz G, Moebus V, Bergh J, Pritchard KI, Bliss J, Cameron D, Evans V, Pan H, Peto R, Bradley R, Gray R.

Lancet. 2015 Oct 3;386(10001):1353-61. doi: 10.1016/S0140-6736(15)60908-4. Erratum in: Lancet. 2016 Jan 2;387(10013):30.


Breast Cancer Risk Reduction, Version 2.2015.

Bevers TB, Ward JH, Arun BK, Colditz GA, Cowan KH, Daly MB, Garber JE, Gemignani ML, Gradishar WJ, Jordan JA, Korde LA, Kounalakis N, Krontiras H, Kumar S, Kurian A, Laronga C, Layman RM, Loftus LS, Mahoney MC, Merajver SD, Meszoely IM, Mortimer J, Newman L, Pritchard E, Pruthi S, Seewaldt V, Specht MC, Visvanathan K, Wallace A, Bergman MA, Kumar R.

J Natl Compr Canc Netw. 2015 Jul;13(7):880-915.


Research priorities in mesothelioma: A James Lind Alliance Priority Setting Partnership.

Stephens RJ, Whiting C, Cowan K; James Lind Alliance Mesothelioma Priority Setting Partnership Steering Committee..

Lung Cancer. 2015 Aug;89(2):175-80. doi: 10.1016/j.lungcan.2015.05.021.


Two PALB2 germline mutations found in both BRCA1+ and BRCAx familial breast cancer.

Downs B, Kim YC, Xiao F, Snyder C, Chen P, Fleissner EA, Becirovic D, Wen H, Sherman S, Cowan KH, Lynch HT, Wang SM.

Breast Cancer Res Treat. 2015 May;151(1):219-24. doi: 10.1007/s10549-015-3358-7.


Exome analysis reveals differentially mutated gene signatures of stage, grade and subtype in breast cancers.

Li Y, Wang X, Vural S, Mishra NK, Cowan KH, Guda C.

PLoS One. 2015 Mar 24;10(3):e0119383. doi: 10.1371/journal.pone.0119383.


Awareness of Federal Regulatory Mechanisms Relevant to Community-Engaged Research: Survey of Health Disparities-Oriented NIH-Funded Investigators.

Fullerton SM, Anderson EE, Cowan K, Malen RC, Brugge D.

J Empir Res Hum Res Ethics. 2015 Feb;10(1):13-21. doi: 10.1177/1556264614561964.


Setting research priorities to improve the health of children and young people with neurodisability: a British Academy of Childhood Disability-James Lind Alliance Research Priority Setting Partnership.

Morris C, Simkiss D, Busk M, Morris M, Allard A, Denness J, Janssens A, Stimson A, Coghill J, Robinson K, Fenton M, Cowan K.

BMJ Open. 2015 Jan 28;5(1):e006233. doi: 10.1136/bmjopen-2014-006233.


Sparse modeling of spatial environmental variables associated with asthma.

Chang TS, Gangnon RE, David Page C, Buckingham WR, Tandias A, Cowan KJ, Tomasallo CD, Arndt BG, Hanrahan LP, Guilbert TW.

J Biomed Inform. 2015 Feb;53:320-9. doi: 10.1016/j.jbi.2014.12.005.


Top ten research priorities for spinal cord injury.

van Middendorp JJ, Allison H, Cowan K; Spinal Cord Injury Priority Setting Partnership..

Lancet Neurol. 2014 Dec;13(12):1167. doi: 10.1016/S1474-4422(14)70253-4. No abstract available.


Inhibition of RAC1 GTPase sensitizes pancreatic cancer cells to ╬│-irradiation.

Yan Y, Hein AL, Etekpo A, Burchett KM, Lin C, Enke CA, Batra SK, Cowan KH, Ouellette MM.

Oncotarget. 2014 Nov 15;5(21):10251-70.


Pannexin 1 and pannexin 3 channels regulate skeletal muscle myoblast proliferation and differentiation.

Langlois S, Xiang X, Young K, Cowan BJ, Penuela S, Cowan KN.

J Biol Chem. 2014 Oct 31;289(44):30717-31. doi: 10.1074/jbc.M114.572131.

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