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Items: 1 to 20 of 137

1.

The Effects of UDP-sugars, UDP, and Mg2+ on Uridine Diphosphate Glucuronosyltransferase Activity in Human Liver Microsomes.

Walia G, Smith AD, Riches Z, Collier AC, Coughtrie MWH.

Xenobiotica. 2017 Sep 4:1-32. doi: 10.1080/00498254.2017.1376260. [Epub ahead of print]

PMID:
28868965
2.

Revisiting the Latency of Uridine Diphosphate-Glucuronosyltransferases (UGTs)-How Does the Endoplasmic Reticulum Membrane Influence Their Function?

Liu Y, Coughtrie MWH.

Pharmaceutics. 2017 Aug 30;9(3). pii: E32. doi: 10.3390/pharmaceutics9030032. Review.

3.

Influence of Morbid Obesity on the Pharmacokinetics of Morphine, Morphine-3-Glucuronide, and Morphine-6-Glucuronide.

de Hoogd S, Välitalo PAJ, Dahan A, van Kralingen S, Coughtrie MMW, van Dongen EPA, van Ramshorst B, Knibbe CAJ.

Clin Pharmacokinet. 2017 May 16. doi: 10.1007/s40262-017-0544-2. [Epub ahead of print]

PMID:
28510797
4.

Function and organization of the human cytosolic sulfotransferase (SULT) family.

Coughtrie MW.

Chem Biol Interact. 2016 Nov 25;259(Pt A):2-7. doi: 10.1016/j.cbi.2016.05.005. Epub 2016 May 9. Review.

PMID:
27174136
5.

The heparan sulfate sulfotransferase 3-OST3A (HS3ST3A) is a novel tumor regulator and a prognostic marker in breast cancer.

Mao X, Gauche C, Coughtrie MW, Bui C, Gulberti S, Merhi-Soussi F, Ramalanjaona N, Bertin-Jung I, Diot A, Dumas D, De Freitas Caires N, Thompson AM, Bourdon JC, Ouzzine M, Fournel-Gigleux S.

Oncogene. 2016 Sep 22;35(38):5043-55. doi: 10.1038/onc.2016.44. Epub 2016 Apr 4.

PMID:
27041583
6.

Ontogeny of Human Conjugating Enzymes.

Coughtrie MW.

Drug Metab Lett. 2015;9(2):99-108. Review.

PMID:
26031463
7.

Characterization of bovine phenol sulfotransferases: evidence of a major role for SULT1B1 in the liver.

Choughule KV, Locuson CW, Coughtrie MW.

Xenobiotica. 2015;45(6):495-502. doi: 10.3109/00498254.2014.997325. Epub 2014 Dec 24.

PMID:
25539458
8.

Effect of nicotine patches in pregnancy on infant and maternal outcomes at 2 years: follow-up from the randomised, double-blind, placebo-controlled SNAP trial.

Cooper S, Taggar J, Lewis S, Marlow N, Dickinson A, Whitemore R, Coleman T; Smoking, Nicotine and Pregnancy (SNAP) Trial Team.

Lancet Respir Med. 2014 Sep;2(9):728-37. doi: 10.1016/S2213-2600(14)70157-2. Epub 2014 Aug 10. Erratum in: Lancet Respir Med. 2014 Nov;2(11):e22.

9.

Rising antipsychotic prescriptions for children and youth: cross-sectoral solutions for a multimodal problem.

Di Pietro N, Illes J; Canadian Working Group on Antipsychotic Medications and Children.

CMAJ. 2014 Jun 10;186(9):653-4. doi: 10.1503/cmaj.131604. Epub 2014 Mar 24. Review. No abstract available.

10.

Luminal accumulation of newly synthesized morphine-3-glucuronide in rat liver microsomal vesicles.

Révész K, Tóth B, Staines AG, Coughtrie MW, Mandl J, Csala M.

Biofactors. 2013 May-Jun;39(3):271-8. doi: 10.1002/biof.1067. Epub 2012 Dec 22.

PMID:
23281118
11.

Neonatal development of hepatic UGT1A9: implications of pediatric pharmacokinetics.

Miyagi SJ, Milne AM, Coughtrie MW, Collier AC.

Drug Metab Dispos. 2012 Jul;40(7):1321-7. doi: 10.1124/dmd.111.043752. Epub 2012 Apr 5.

12.

A randomized trial of nicotine-replacement therapy patches in pregnancy.

Coleman T, Cooper S, Thornton JG, Grainge MJ, Watts K, Britton J, Lewis S; Smoking, Nicotine, and Pregnancy (SNAP) Trial Team.

N Engl J Med. 2012 Mar 1;366(9):808-18. doi: 10.1056/NEJMoa1109582.

13.

Chondroitin sulfate N-acetylgalactosaminyltransferase-1 (CSGalNAcT-1) involved in chondroitin sulfate initiation: Impact of sulfation on activity and specificity.

Gulberti S, Jacquinet JC, Chabel M, Ramalanjaona N, Magdalou J, Netter P, Coughtrie MW, Ouzzine M, Fournel-Gigleux S.

Glycobiology. 2012 Apr;22(4):561-71. doi: 10.1093/glycob/cwr172. Epub 2011 Dec 7.

PMID:
22156920
14.

Absolute immunoquantification of the expression of ABC transporters P-glycoprotein, breast cancer resistance protein and multidrug resistance-associated protein 2 in human liver and duodenum.

Tucker TG, Milne AM, Fournel-Gigleux S, Fenner KS, Coughtrie MW.

Biochem Pharmacol. 2012 Jan 15;83(2):279-85. doi: 10.1016/j.bcp.2011.10.017. Epub 2011 Oct 31.

PMID:
22062654
15.

A novel method for the immunoquantification of UDP-glucuronosyltransferases in human tissue.

Milne AM, Burchell B, Coughtrie MW.

Drug Metab Dispos. 2011 Dec;39(12):2258-63. doi: 10.1124/dmd.111.041699. Epub 2011 Aug 31.

16.

Antiplatelet drug interactions.

Mackenzie IS, Coughtrie MW, MacDonald TM, Wei L.

J Intern Med. 2010 Dec;268(6):516-29. doi: 10.1111/j.1365-2796.2010.02299.x. Epub 2010 Nov 14. Review.

17.

Identification of key functional residues in the active site of human {beta}1,4-galactosyltransferase 7: a major enzyme in the glycosaminoglycan synthesis pathway.

Talhaoui I, Bui C, Oriol R, Mulliert G, Gulberti S, Netter P, Coughtrie MW, Ouzzine M, Fournel-Gigleux S.

J Biol Chem. 2010 Nov 26;285(48):37342-58. doi: 10.1074/jbc.M110.151951. Epub 2010 Sep 14.

18.

Molecular characterization of β1,4-galactosyltransferase 7 genetic mutations linked to the progeroid form of Ehlers-Danlos syndrome (EDS).

Bui C, Talhaoui I, Chabel M, Mulliert G, Coughtrie MW, Ouzzine M, Fournel-Gigleux S.

FEBS Lett. 2010 Sep 24;584(18):3962-8. doi: 10.1016/j.febslet.2010.08.001. Epub 2010 Aug 6.

19.

The use of hepatocytes to investigate UDP-glucuronosyltransferases and sulfotransferases.

Fournel-Gigleux S, Coughtrie MW, Ouzzine M, Magdalou J.

Methods Mol Biol. 2010;640:309-26. doi: 10.1007/978-1-60761-688-7_17.

PMID:
20645060
20.

Epigenetics: methylation-associated repression of heparan sulfate 3-O-sulfotransferase gene expression contributes to the invasive phenotype of H-EMC-SS chondrosarcoma cells.

Bui C, Ouzzine M, Talhaoui I, Sharp S, Prydz K, Coughtrie MW, Fournel-Gigleux S.

FASEB J. 2010 Feb;24(2):436-50. doi: 10.1096/fj.09-136291. Epub 2009 Oct 7.

PMID:
19812376

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