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Diffusion of Immunoglobulin G in Shed Vaginal Epithelial Cells and in Cell-Free Regions of Human Cervicovaginal Mucus.

Wang YY, Schroeder HA, Nunn KL, Woods K, Anderson DJ, Lai SK, Cone RA.

PLoS One. 2016 Jun 30;11(6):e0158338. doi: 10.1371/journal.pone.0158338.


Antimicrobial and immune modulatory effects of lactic acid and short chain fatty acids produced by vaginal microbiota associated with eubiosis and bacterial vaginosis.

Aldunate M, Srbinovski D, Hearps AC, Latham CF, Ramsland PA, Gugasyan R, Cone RA, Tachedjian G.

Front Physiol. 2015 Jun 2;6:164. doi: 10.3389/fphys.2015.00164. Review.


Vaginal microbiota and sexually transmitted infections that may influence transmission of cell-associated HIV.

Cone RA.

J Infect Dis. 2014 Dec 15;210 Suppl 3:S616-21. doi: 10.1093/infdis/jiu459. Review.


Vaginal pH and microbicidal lactic acid when lactobacilli dominate the microbiota.

O'Hanlon DE, Moench TR, Cone RA.

PLoS One. 2013 Nov 6;8(11):e80074. doi: 10.1371/journal.pone.0080074.


Drug-induced reactivation of apoptosis abrogates HIV-1 infection.

Hanauske-Abel HM, Saxena D, Palumbo PE, Hanauske AR, Luchessi AD, Cambiaghi TD, Hoque M, Spino M, D'Alliessi Gandolfi D, Heller DS, Singh S, Park MH, Cracchiolo BM, Tricta F, Connelly J, Popowicz AM, Cone RA, Holland B, Pe'ery T, Mathews MB.

PLoS One. 2013 Sep 23;8(9):e74414. doi: 10.1371/journal.pone.0074414.


Enhanced vaginal drug delivery through the use of hypotonic formulations that induce fluid uptake.

Ensign LM, Hoen TE, Maisel K, Cone RA, Hanes JS.

Biomaterials. 2013 Sep;34(28):6922-9. doi: 10.1016/j.biomaterials.2013.05.039.


Nanoparticle diffusion in, and microrheology of, the bovine vitreous ex vivo.

Xu Q, Boylan NJ, Suk JS, Wang YY, Nance EA, Yang JC, McDonnell PJ, Cone RA, Duh EJ, Hanes J.

J Control Release. 2013 Apr 10;167(1):76-84. doi: 10.1016/j.jconrel.2013.01.018.


Evaluation of microbicide gel adherence monitoring methods.

Moench TR, O'Hanlon DE, Cone RA.

Sex Transm Dis. 2012 May;39(5):335-40. doi: 10.1097/OLQ.0b013e31824790bb.


In vaginal fluid, bacteria associated with bacterial vaginosis can be suppressed with lactic acid but not hydrogen peroxide.

O'Hanlon DE, Moench TR, Cone RA.

BMC Infect Dis. 2011 Jul 19;11:200. doi: 10.1186/1471-2334-11-200.


Novel approaches to vaginal delivery and safety of microbicides: biopharmaceuticals, nanoparticles, and vaccines.

Whaley KJ, Hanes J, Shattock R, Cone RA, Friend DR.

Antiviral Res. 2010 Dec;88 Suppl 1:S55-66. doi: 10.1016/j.antiviral.2010.09.006.


Microbicide excipients can greatly increase susceptibility to genital herpes transmission in the mouse.

Moench TR, Mumper RJ, Hoen TE, Sun M, Cone RA.

BMC Infect Dis. 2010 Nov 18;10:331. doi: 10.1186/1471-2334-10-331.


Rapid fluctuation of the vaginal microbiota measured by Gram stain analysis.

Brotman RM, Ravel J, Cone RA, Zenilman JM.

Sex Transm Infect. 2010 Aug;86(4):297-302. doi: 10.1136/sti.2009.040592.


Cervicovaginal fluid and semen block the microbicidal activity of hydrogen peroxide produced by vaginal lactobacilli.

O'Hanlon DE, Lanier BR, Moench TR, Cone RA.

BMC Infect Dis. 2010 May 19;10:120. doi: 10.1186/1471-2334-10-120.


Barrier properties of mucus.

Cone RA.

Adv Drug Deliv Rev. 2009 Feb 27;61(2):75-85. doi: 10.1016/j.addr.2008.09.008. Review.


Formulating a sulfonated antiviral dendrimer in a vaginal microbicidal gel having dual mechanisms of action.

Mumper RJ, Bell MA, Worthen DR, Cone RA, Lewis GR, Paull JR, Moench TR.

Drug Dev Ind Pharm. 2009 May;35(5):515-24. doi: 10.1080/03639040802488097.


Vaginal microbicides: detecting toxicities in vivo that paradoxically increase pathogen transmission.

Cone RA, Hoen T, Wong X, Abusuwwa R, Anderson DJ, Moench TR.

BMC Infect Dis. 2006 Jun 1;6:90.


Low pH immobilizes and kills human leukocytes and prevents transmission of cell-associated HIV in a mouse model.

Olmsted SS, Khanna KV, Ng EM, Whitten ST, Johnson ON 3rd, Markham RB, Cone RA, Moench TR.

BMC Infect Dis. 2005 Sep 30;5:79.


A self-sampling method to obtain large volumes of undiluted cervicovaginal secretions.

Boskey ER, Moench TR, Hees PS, Cone RA.

Sex Transm Dis. 2003 Feb;30(2):107-9.


Microbicide efficacy and toxicity tests in a mouse model for vaginal transmission of Chlamydia trachomatis.

Achilles SL, Shete PB, Whaley KJ, Moench TR, Cone RA.

Sex Transm Dis. 2002 Nov;29(11):655-64.


Human monoclonal antibody stability and activity at vaginal pH.

Castle PE, Karp DA, Zeitlin L, GarcĂ­a-Moreno E B, Moench TR, Whaley KJ, Cone RA.

J Reprod Immunol. 2002 Jul-Aug;56(1-2):61-76.


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