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Items: 1 to 20 of 69


Sub-lethal oxidative stress induces lysosome biogenesis via a lysosomal membrane permeabilization-cathepsin-caspase 3-transcription factor EB-dependent pathway.

Leow SM, Chua SX, Venkatachalam G, Shen L, Luo L, Clement MV.

Oncotarget. 2017 Mar 7;8(10):16170-16189. doi: 10.18632/oncotarget.14016.


Manganese Superoxide Dismutase Expression Regulates the Switch Between an Epithelial and a Mesenchymal-Like Phenotype in Breast Carcinoma.

Loo SY, Hirpara JL, Pandey V, Tan TZ, Yap CT, Lobie PE, Thiery JP, Goh BC, Pervaiz S, Clément MV, Kumar AP.

Antioxid Redox Signal. 2016 Aug 20;25(6):283-99. doi: 10.1089/ars.2015.6524.


Breast Cancer: A Molecular and Redox Snapshot.

Raman D, Foo CH, Clement MV, Pervaiz S.

Antioxid Redox Signal. 2016 Aug 20;25(6):337-70. doi: 10.1089/ars.2015.6546. Epub 2016 Jun 17. Review.


Non-canonical Activation of Akt in Serum-Stimulated Fibroblasts, Revealed by Comparative Modeling of Pathway Dynamics.

Nim TH, Luo L, White JK, Clément MV, Tucker-Kellogg L.

PLoS Comput Biol. 2015 Nov 10;11(11):e1004505. doi: 10.1371/journal.pcbi.1004505. eCollection 2015 Nov.


The prognostic value of the stem-like group in colorectal cancer using a panel of immunohistochemistry markers.

Ong CW, Chong PY, McArt DG, Chan JY, Tan HT, Kumar AP, Chung MC, Clément MV, Soong R, Van Schaeybroeck S, Waugh DJ, Johnston PG, Dunne PD, Salto-Tellez M.

Oncotarget. 2015 May 20;6(14):12763-73.


Formation of protein S-nitrosylation by reactive oxygen species.

Hlaing KH, Clément MV.

Free Radic Res. 2014 Sep;48(9):996-1010. doi: 10.3109/10715762.2014.942842.


OpenComet: an automated tool for comet assay image analysis.

Gyori BM, Venkatachalam G, Thiagarajan PS, Hsu D, Clement MV.

Redox Biol. 2014 Jan 9;2:457-65. doi: 10.1016/j.redox.2013.12.020. eCollection 2014.


Manganese superoxide dismutase is a promising target for enhancing chemosensitivity of basal-like breast carcinoma.

Kumar AP, Loo SY, Shin SW, Tan TZ, Eng CB, Singh R, Putti TC, Ong CW, Salto-Tellez M, Goh BC, Park JI, Thiery JP, Pervaiz S, Clement MV.

Antioxid Redox Signal. 2014 May 20;20(15):2326-46. doi: 10.1089/ars.2013.5295. Epub 2013 Nov 14.


A distinct reactive oxygen species profile confers chemoresistance in glioma-propagating cells and associates with patient survival outcome.

Koh LW, Koh GR, Ng FS, Toh TB, Sandanaraj E, Chong YK, Phong M, Tucker-Kellogg G, Kon OL, Ng WH, Ng IH, Clement MV, Pervaiz S, Ang BT, Tang CS.

Antioxid Redox Signal. 2013 Dec 20;19(18):2261-79. doi: 10.1089/ars.2012.4999. Epub 2013 Apr 12.


Systematic parameter estimation in data-rich environments for cell signalling dynamics.

Nim TH, Luo L, Clément MV, White JK, Tucker-Kellogg L.

Bioinformatics. 2013 Apr 15;29(8):1044-51. doi: 10.1093/bioinformatics/btt083. Epub 2013 Feb 19.


PTEN/Akt signaling controls mitochondrial respiratory capacity through 4E-BP1.

Goo CK, Lim HY, Ho QS, Too HP, Clement MV, Wong KP.

PLoS One. 2012;7(9):e45806. doi: 10.1371/journal.pone.0045806. Epub 2012 Sep 26.


Redox control of cytosolic Akt phosphorylation in PTEN null cells.

Luo L, Kaur Kumar J, Clément MV.

Free Radic Biol Med. 2012 Nov 1;53(9):1697-707. doi: 10.1016/j.freeradbiomed.2012.08.566. Epub 2012 Aug 19.


NHE-1: a promising target for novel anti-cancer therapeutics.

Loo SY, Chang MK, Chua CS, Kumar AP, Pervaiz S, Clement MV.

Curr Pharm Des. 2012;18(10):1372-82. Review.


PPARγ disease gene network and identification of therapeutic targets for prostate cancer.

Venkatachalam G, Kumar AP, Sakharkar KR, Thangavel S, Clement MV, Sakharkar MK.

J Drug Target. 2011 Nov;19(9):781-96. doi: 10.3109/1061186X.2011.568062. Epub 2011 Jul 23.


The small GTPase Rac1 is a novel binding partner of Bcl-2 and stabilizes its antiapoptotic activity.

Velaithan R, Kang J, Hirpara JL, Loh T, Goh BC, Le Bras M, Brenner C, Clement MV, Pervaiz S.

Blood. 2011 Jun 9;117(23):6214-26. doi: 10.1182/blood-2010-08-301283. Epub 2011 Apr 7.


Activation of a non-genomic Pim-1/Bad-Pser75 module is required for an efficient pro-survival effect of Bcl-xL induced by androgen in LNCaP cells.

Kumar JK, Ping RY, Teong HF, Goh S, Clément MV.

Int J Biochem Cell Biol. 2011 Apr;43(4):594-603. doi: 10.1016/j.biocel.2010.12.017. Epub 2010 Dec 25.


Computational identification and experimental validation of PPRE motifs in NHE1 and MnSOD genes of human.

Venkatachalam G, Kumar AP, Yue LS, Pervaiz S, Clement MV, Sakharkar MK.

BMC Genomics. 2009 Dec 3;10 Suppl 3:S5. doi: 10.1186/1471-2164-10-S3-S5.


Repression of NHE1 expression by PPARgamma activation is a potential new approach for specific inhibition of the growth of tumor cells in vitro and in vivo.

Kumar AP, Quake AL, Chang MK, Zhou T, Lim KS, Singh R, Hewitt RE, Salto-Tellez M, Pervaiz S, Clément MV.

Cancer Res. 2009 Nov 15;69(22):8636-44. doi: 10.1158/0008-5472.CAN-09-0219. Epub 2009 Nov 3.


Resveratrol regulates the expression of NHE-1 by repressing its promoter activity: critical involvement of intracellular H2O2 and caspases 3 and 6 in the absence of cell death.

Jhumka Z, Pervaiz S, Clément MV.

Int J Biochem Cell Biol. 2009 Apr;41(4):945-56. doi: 10.1016/j.biocel.2008.09.028. Epub 2008 Oct 4.


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