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Items: 12

1.

High-throughput discovery of novel developmental phenotypes.

Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A; International Mouse Phenotyping Consortium; Jackson Laboratory; Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource Center, MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bućan M, Murray SA.

Nature. 2016 Sep 22;537(7621):508-514. doi: 10.1038/nature19356. Epub 2016 Sep 14.

2.

The architecture of parent-of-origin effects in mice.

Mott R, Yuan W, Kaisaki P, Gan X, Cleak J, Edwards A, Baud A, Flint J.

Cell. 2014 Jan 16;156(1-2):332-42. doi: 10.1016/j.cell.2013.11.043.

3.

The genome architecture of the Collaborative Cross mouse genetic reference population.

Collaborative Cross Consortium.

Genetics. 2012 Feb;190(2):389-401. doi: 10.1534/genetics.111.132639.

4.

Sequence-based characterization of structural variation in the mouse genome.

Yalcin B, Wong K, Agam A, Goodson M, Keane TM, Gan X, Nellåker C, Goodstadt L, Nicod J, Bhomra A, Hernandez-Pliego P, Whitley H, Cleak J, Dutton R, Janowitz D, Mott R, Adams DJ, Flint J.

Nature. 2011 Sep 14;477(7364):326-9. doi: 10.1038/nature10432.

5.

Mouse genomic variation and its effect on phenotypes and gene regulation.

Keane TM, Goodstadt L, Danecek P, White MA, Wong K, Yalcin B, Heger A, Agam A, Slater G, Goodson M, Furlotte NA, Eskin E, Nellåker C, Whitley H, Cleak J, Janowitz D, Hernandez-Pliego P, Edwards A, Belgard TG, Oliver PL, McIntyre RE, Bhomra A, Nicod J, Gan X, Yuan W, van der Weyden L, Steward CA, Bala S, Stalker J, Mott R, Durbin R, Jackson IJ, Czechanski A, Guerra-Assunção JA, Donahue LR, Reinholdt LG, Payseur BA, Ponting CP, Birney E, Flint J, Adams DJ.

Nature. 2011 Sep 14;477(7364):289-94. doi: 10.1038/nature10413.

6.

Cytoarchitectural disruption of the superior colliculus and an enlarged acoustic startle response in the Tuba1a mutant mouse.

Edwards A, Treiber CD, Breuss M, Pidsley R, Huang GJ, Cleak J, Oliver PL, Flint J, Keays DA.

Neuroscience. 2011 Nov 10;195:191-200. doi: 10.1016/j.neuroscience.2011.08.035. Epub 2011 Aug 22.

7.

Collaborative Cross mice and their power to map host susceptibility to Aspergillus fumigatus infection.

Durrant C, Tayem H, Yalcin B, Cleak J, Goodstadt L, de Villena FP, Mott R, Iraqi FA.

Genome Res. 2011 Aug;21(8):1239-48. doi: 10.1101/gr.118786.110. Epub 2011 Apr 14.

8.

The role of Tuba1a in adult hippocampal neurogenesis and the formation of the dentate gyrus.

Keays DA, Cleak J, Huang GJ, Edwards A, Braun A, Treiber CD, Pidsley R, Flint J.

Dev Neurosci. 2010;32(4):268-77. doi: 10.1159/000319663. Epub 2010 Oct 30.

9.

Commercially available outbred mice for genome-wide association studies.

Yalcin B, Nicod J, Bhomra A, Davidson S, Cleak J, Farinelli L, Østerås M, Whitley A, Yuan W, Gan X, Goodson M, Klenerman P, Satpathy A, Mathis D, Benoist C, Adams DJ, Mott R, Flint J.

PLoS Genet. 2010 Sep 2;6(9):e1001085. doi: 10.1371/journal.pgen.1001085.

10.

Genetic and phenotypic effects of phonological short-term memory and grammatical morphology in specific language impairment.

Falcaro M, Pickles A, Newbury DF, Addis L, Banfield E, Fisher SE, Monaco AP, Simkin Z, Conti-Ramsden G; SLI Consortium.

Genes Brain Behav. 2008 Jun;7(4):393-402. Epub 2007 Nov 12.

11.

Mapping regulatory variants for the serotonin transporter gene based on allelic expression imbalance.

Martin J, Cleak J, Willis-Owen SA, Flint J, Shifman S.

Mol Psychiatry. 2007 May;12(5):421-2. No abstract available. Erratum in: Mol Psychiatry. 2007 Sep;12(9):881.

PMID:
17453058
12.

Mutations in alpha-tubulin cause abnormal neuronal migration in mice and lissencephaly in humans.

Keays DA, Tian G, Poirier K, Huang GJ, Siebold C, Cleak J, Oliver PL, Fray M, Harvey RJ, Molnár Z, Piñon MC, Dear N, Valdar W, Brown SD, Davies KE, Rawlins JN, Cowan NJ, Nolan P, Chelly J, Flint J.

Cell. 2007 Jan 12;128(1):45-57.

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