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Items: 1 to 20 of 44

1.

Disruption of pdgfra alters endocardial and myocardial fusion during zebrafish cardiac assembly.

El-Rass S, Eisa-Beygi S, Khong E, Brand-Arzamendi K, Mauro A, Zhang H, Clark KJ, Ekker SC, Wen XY.

Biol Open. 2017 Mar 15;6(3):348-357. doi: 10.1242/bio.021212.

2.

Functional characterization of a GFAP variant of uncertain significance in an Alexander disease case within the setting of an individualized medicine clinic.

Boczek NJ, Sigafoos AN, Zimmermann MT, Maus RL, Cousin MA, Blackburn PR, Urrutia R, Clark KJ, Patterson MC, Wick MJ, Klee EW.

Clin Case Rep. 2016 Aug 15;4(9):885-95. doi: 10.1002/ccr3.655. eCollection 2016 Sep.

3.

Silent Tyrosinemia Type I Without Elevated Tyrosine or Succinylacetone Associated with Liver Cirrhosis and Hepatocellular Carcinoma.

Blackburn PR, Hickey RD, Nace RA, Giama NH, Kraft DL, Bordner AJ, Chaiteerakij R, McCormick JB, Radulovic M, Graham RP, Torbenson MS, Tortorelli S, Scott CR, Lindor NM, Milliner DS, Oglesbee D, Al-Qabandi W, Grompe M, Gavrilov DK, El-Youssef M, Clark KJ, Atwal PS, Roberts LR, Klee EW, Ekker SC.

Hum Mutat. 2016 Oct;37(10):1097-105. doi: 10.1002/humu.23047. Epub 2016 Aug 8.

4.

GoldyTALEN Vectors with Improved Efficiency for Golden Gate TALEN Assembly.

Welker JM, Wierson WA, Wang Y, Poshusta TL, McNulty MS, Tisdale EE, Solin SL, Ekker SC, Clark KJ, McGrail M, Essner JJ.

Hum Gene Ther. 2016 Jun;27(6):423-4. doi: 10.1089/hum.2016.012. Epub 2016 May 6. No abstract available.

5.

Genome Engineering with TALE and CRISPR Systems in Neuroscience.

Lee HB, Sundberg BN, Sigafoos AN, Clark KJ.

Front Genet. 2016 Apr 6;7:47. doi: 10.3389/fgene.2016.00047. eCollection 2016. Review.

6.

Mayo Clinic Zebrafish Facility Overview.

Leveque RE, Clark KJ, Ekker SC.

Zebrafish. 2016 Jul;13 Suppl 1:S44-6. doi: 10.1089/zeb.2015.1227. Epub 2016 Mar 29.

7.

A highly infective plant-associated bacterium influences reproductive rates in pea aphids.

Hendry TA, Clark KJ, Baltrus DA.

R Soc Open Sci. 2016 Feb 10;3(2):150478. doi: 10.1098/rsos.150478. eCollection 2016 Feb.

8.

Allele-Specific Quantitative PCR for Accurate, Rapid, and Cost-Effective Genotyping.

Lee HB, Schwab TL, Koleilat A, Ata H, Daby CL, Cervera RL, McNulty MS, Bostwick HS, Clark KJ.

Hum Gene Ther. 2016 Jun;27(6):425-35. doi: 10.1089/hum.2016.011. Epub 2016 Mar 17.

9.

FusX: A Rapid One-Step Transcription Activator-Like Effector Assembly System for Genome Science.

Ma AC, McNulty MS, Poshusta TL, Campbell JM, Martínez-Gálvez G, Argue DP, Lee HB, Urban MD, Bullard CE, Blackburn PR, Man TK, Clark KJ, Ekker SC.

Hum Gene Ther. 2016 Jun;27(6):451-63. doi: 10.1089/hum.2015.172. Epub 2016 Mar 15.

10.

Elucidating cannabinoid biology in zebrafish (Danio rerio).

Krug RG 2nd, Clark KJ.

Gene. 2015 Oct 10;570(2):168-79. doi: 10.1016/j.gene.2015.07.036. Epub 2015 Jul 17. Review.

11.

Protein-Trap Insertional Mutagenesis Uncovers New Genes Involved in Zebrafish Skin Development, Including a Neuregulin 2a-Based ErbB Signaling Pathway Required during Median Fin Fold Morphogenesis.

Westcot SE, Hatzold J, Urban MD, Richetti SK, Skuster KJ, Harm RM, Lopez Cervera R, Umemoto N, McNulty MS, Clark KJ, Hammerschmidt M, Ekker SC.

PLoS One. 2015 Jun 25;10(6):e0130688. doi: 10.1371/journal.pone.0130688. eCollection 2015.

12.

Multiple factors influence the contribution of individual immunoglobulin light chain genes to the naïve antibody repertoire.

Fitzsimmons SP, Aydanian AG, Clark KJ, Shapiro MA.

BMC Immunol. 2014 Oct 30;15:51. doi: 10.1186/s12865-014-0051-2.

13.

Making designer mutants in model organisms.

Peng Y, Clark KJ, Campbell JM, Panetta MR, Guo Y, Ekker SC.

Development. 2014 Nov;141(21):4042-54. doi: 10.1242/dev.102186. Review.

14.

A transgenic zebrafish model for monitoring glucocorticoid receptor activity.

Krug RG 2nd, Poshusta TL, Skuster KJ, Berg MR, Gardner SL, Clark KJ.

Genes Brain Behav. 2014 Jun;13(5):478-87. doi: 10.1111/gbb.12135. Epub 2014 Apr 22.

15.

High efficiency In Vivo genome engineering with a simplified 15-RVD GoldyTALEN design.

Ma AC, Lee HB, Clark KJ, Ekker SC.

PLoS One. 2013 May 29;8(5):e65259. doi: 10.1371/journal.pone.0065259. Print 2013.

16.

A sequence-based variation map of zebrafish.

Patowary A, Purkanti R, Singh M, Chauhan R, Singh AR, Swarnkar M, Singh N, Pandey V, Torroja C, Clark MD, Kocher JP, Clark KJ, Stemple DL, Klee EW, Ekker SC, Scaria V, Sivasubbu S.

Zebrafish. 2013 Mar;10(1):15-20. doi: 10.1089/zeb.2012.0848.

17.

The CRISPR system--keeping zebrafish gene targeting fresh.

Blackburn PR, Campbell JM, Clark KJ, Ekker SC.

Zebrafish. 2013 Mar;10(1):116-8. doi: 10.1089/zeb.2013.9999. Epub 2013 Mar 28. Review.

18.

Mojo Hand, a TALEN design tool for genome editing applications.

Neff KL, Argue DP, Ma AC, Lee HB, Clark KJ, Ekker SC.

BMC Bioinformatics. 2013 Jan 16;14:1. doi: 10.1186/1471-2105-14-1.

19.

Trapping cardiac recessive mutants via expression-based insertional mutagenesis screening.

Ding Y, Liu W, Deng Y, Jomok B, Yang J, Huang W, Clark KJ, Zhong TP, Lin X, Ekker SC, Xu X.

Circ Res. 2013 Feb 15;112(4):606-17. doi: 10.1161/CIRCRESAHA.112.300603. Epub 2013 Jan 2.

20.

An in vivo method to quantify lymphangiogenesis in zebrafish.

Hoffman SJ, Psaltis PJ, Clark KJ, Spoon DB, Chue CD, Ekker SC, Simari RD.

PLoS One. 2012;7(9):e45240. doi: 10.1371/journal.pone.0045240. Epub 2012 Sep 13.

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