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Items: 1 to 20 of 55

1.

A Smoking-Associated miRNA-mRNA Coexpression Network.

Civelek M.

Circ Cardiovasc Genet. 2017 Oct;10(5). pii: e001914. doi: 10.1161/CIRCGENETICS.117.001914. No abstract available.

PMID:
29030404
2.

Identification of breast cancer associated variants that modulate transcription factor binding.

Liu Y, Walavalkar NM, Dozmorov MG, Rich SS, Civelek M, Guertin MJ.

PLoS Genet. 2017 Sep 28;13(9):e1006761. doi: 10.1371/journal.pgen.1006761. eCollection 2017 Sep.

3.

Trans-ancestry Fine Mapping and Molecular Assays Identify Regulatory Variants at the ANGPTL8 HDL-C GWAS Locus.

Cannon ME, Duan Q, Wu Y, Zeynalzadeh M, Xu Z, Kangas AJ, Soininen P, Ala-Korpela M, Civelek M, Lusis AJ, Kuusisto J, Collins FS, Boehnke M, Tang H, Laakso M, Li Y, Mohlke KL.

G3 (Bethesda). 2017 Sep 7;7(9):3217-3227. doi: 10.1534/g3.117.300088.

4.

The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue.

Schugar RC, Shih DM, Warrier M, Helsley RN, Burrows A, Ferguson D, Brown AL, Gromovsky AD, Heine M, Chatterjee A, Li L, Li XS, Wang Z, Willard B, Meng Y, Kim H, Che N, Pan C, Lee RG, Crooke RM, Graham MJ, Morton RE, Langefeld CD, Das SK, Rudel LL, Zein N, McCullough AJ, Dasarathy S, Tang WHW, Erokwu BO, Flask CA, Laakso M, Civelek M, Naga Prasad SV, Heeren J, Lusis AJ, Hazen SL, Brown JM.

Cell Rep. 2017 Jul 5;20(1):279. doi: 10.1016/j.celrep.2017.06.053. No abstract available.

5.

The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue.

Schugar RC, Shih DM, Warrier M, Helsley RN, Burrows A, Ferguson D, Brown AL, Gromovsky AD, Heine M, Chatterjee A, Li L, Li XS, Wang Z, Willard B, Meng Y, Kim H, Che N, Pan C, Lee RG, Crooke RM, Graham MJ, Morton RE, Langefeld CD, Das SK, Rudel LL, Zein N, McCullough AJ, Dasarathy S, Tang WHW, Erokwu BO, Flask CA, Laakso M, Civelek M, Naga Prasad SV, Heeren J, Lusis AJ, Hazen SL, Brown JM.

Cell Rep. 2017 Jun 20;19(12):2451-2461. doi: 10.1016/j.celrep.2017.05.077.

6.

HIF-1α is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium.

Wu D, Huang RT, Hamanaka RB, Krause M, Oh MJ, Kuo CH, Nigdelioglu R, Meliton AY, Witt L, Dai G, Civelek M, Prabhakar NR, Fang Y, Mutlu GM.

Elife. 2017 May 30;6. pii: e25217. doi: 10.7554/eLife.25217.

7.

Functional Characterization of the GUCY1A3 Coronary Artery Disease Risk Locus.

Kessler T, Wobst J, Wolf B, Eckhold J, Vilne B, Hollstein R, von Ameln S, Dang TA, Sager HB, Moritz Rumpf P, Aherrahrou R, Kastrati A, Björkegren JLM, Erdmann J, Lusis AJ, Civelek M, Kaiser FJ, Schunkert H.

Circulation. 2017 Aug 1;136(5):476-489. doi: 10.1161/CIRCULATIONAHA.116.024152. Epub 2017 May 9.

PMID:
28487391
8.

Cinnamon reduces inflammatory response in intestinal fibroblasts in vitro and in colitis in vivo leading to decreased fibrosis.

Hagenlocher Y, Satzinger S, Civelek M, Feilhauer K, Köninger J, Bischoff SC, Lorentz A.

Mol Nutr Food Res. 2017 Sep;61(9). doi: 10.1002/mnfr.201601085. Epub 2017 May 12.

PMID:
28324642
9.

Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits.

Civelek M, Wu Y, Pan C, Raulerson CK, Ko A, He A, Tilford C, Saleem NK, Stančáková A, Scott LJ, Fuchsberger C, Stringham HM, Jackson AU, Narisu N, Chines PS, Small KS, Kuusisto J, Parks BW, Pajukanta P, Kirchgessner T, Collins FS, Gargalovic PS, Boehnke M, Laakso M, Mohlke KL, Lusis AJ.

Am J Hum Genet. 2017 Mar 2;100(3):428-443. doi: 10.1016/j.ajhg.2017.01.027.

11.

Single nucleotide polymorphisms in an intergenic chromosome 2q region associated with tissue factor pathway inhibitor plasma levels and venous thromboembolism.

Dennis J, Truong V, Aïssi D, Medina-Rivera A, Blankenberg S, Germain M, Lemire M, Antounians L, Civelek M, Schnabel R, Wells P, Wilson MD, Morange PE, Trégouët DA, Gagnon F.

J Thromb Haemost. 2016 Oct;14(10):1960-1970. doi: 10.1111/jth.13431. Epub 2016 Sep 17.

PMID:
27490645
12.

Role of lipid phosphate phosphatase 3 in human aortic endothelial cell function.

Touat-Hamici Z, Weidmann H, Blum Y, Proust C, Durand H, Iannacci F, Codoni V, Gaignard P, Thérond P, Civelek M, Karabina SA, Lusis AJ, Cambien F, Ninio E.

Cardiovasc Res. 2016 Dec;112(3):702-713. Epub 2016 Sep 30.

13.

Preservation Analysis of Macrophage Gene Coexpression Between Human and Mouse Identifies PARK2 as a Genetically Controlled Master Regulator of Oxidative Phosphorylation in Humans.

Codoni V, Blum Y, Civelek M, Proust C, Franzén O; Cardiogenics Consortium; IDEM Leducq Consortium CADGenomics, Björkegren JL, Le Goff W, Cambien F, Lusis AJ, Trégouët DA.

G3 (Bethesda). 2016 Oct 13;6(10):3361-3371. doi: 10.1534/g3.116.033894.

14.

CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis.

Kojima Y, Volkmer JP, McKenna K, Civelek M, Lusis AJ, Miller CL, Direnzo D, Nanda V, Ye J, Connolly AJ, Schadt EE, Quertermous T, Betancur P, Maegdefessel L, Matic LP, Hedin U, Weissman IL, Leeper NJ.

Nature. 2016 Aug 4;536(7614):86-90. Epub 2016 Jul 20.

15.

Effects of milk somatic cell counts on some physicochemical and functional characteristics of skim and whole milk powders.

Sert D, Mercan E, Aydemir S, Civelek M.

J Dairy Sci. 2016 Jul;99(7):5254-5264. doi: 10.3168/jds.2016-10860. Epub 2016 May 11.

PMID:
27179852
16.

Cross-Tissue Regulatory Gene Networks in Coronary Artery Disease.

Talukdar HA, Foroughi Asl H, Jain RK, Ermel R, Ruusalepp A, Franzén O, Kidd BA, Readhead B, Giannarelli C, Kovacic JC, Ivert T, Dudley JT, Civelek M, Lusis AJ, Schadt EE, Skogsberg J, Michoel T, Björkegren JL.

Cell Syst. 2016 Mar 23;2(3):196-208. doi: 10.1016/j.cels.2016.02.002. Epub 2016 Mar 3.

17.

The Hybrid Mouse Diversity Panel: a resource for systems genetics analyses of metabolic and cardiovascular traits.

Lusis AJ, Seldin MM, Allayee H, Bennett BJ, Civelek M, Davis RC, Eskin E, Farber CR, Hui S, Mehrabian M, Norheim F, Pan C, Parks B, Rau CD, Smith DJ, Vallim T, Wang Y, Wang J.

J Lipid Res. 2016 Jun;57(6):925-42. doi: 10.1194/jlr.R066944. Epub 2016 Apr 19. Review.

18.

Correction: Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains.

Bennett BJ, Davis RC, Civelek M, Orozco L, Wu J, Qi H, Pan C, Sevag Packard RR, Eskin E, Yan M, Kirchgessner T, Wang Z, Li X, Gregory JC, Hazen SL, Gargalovic PS, Lusis AJ.

PLoS Genet. 2016 Mar 2;12(3):e1005913. doi: 10.1371/journal.pgen.1005913. eCollection 2016 Mar. No abstract available.

19.

Integrative approaches for large-scale transcriptome-wide association studies.

Gusev A, Ko A, Shi H, Bhatia G, Chung W, Penninx BW, Jansen R, de Geus EJ, Boomsma DI, Wright FA, Sullivan PF, Nikkola E, Alvarez M, Civelek M, Lusis AJ, Lehtimäki T, Raitoharju E, Kähönen M, Seppälä I, Raitakari OT, Kuusisto J, Laakso M, Price AL, Pajukanta P, Pasaniuc B.

Nat Genet. 2016 Mar;48(3):245-52. doi: 10.1038/ng.3506. Epub 2016 Feb 8.

20.

Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains.

Bennett BJ, Davis RC, Civelek M, Orozco L, Wu J, Qi H, Pan C, Packard RR, Eskin E, Yan M, Kirchgessner T, Wang Z, Li X, Gregory JC, Hazen SL, Gargalovic PS, Lusis AJ.

PLoS Genet. 2015 Dec 22;11(12):e1005711. doi: 10.1371/journal.pgen.1005711. eCollection 2015 Dec. Erratum in: PLoS Genet. 2016 Mar;12(3):e1005913.

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