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Items: 1 to 20 of 276

1.

Targeting thrombomodulin to circulating red blood cells augments its protective effects in models of endotoxemia and ischemia-reperfusion injury.

Carnemolla R, Villa CH, Greineder CF, Zaitsev S, Patel KR, Kowalska MA, Atochin DN, Cines DB, Siegel DL, Esmon CT, Muzykantov VR.

FASEB J. 2016 Nov 11. pii: fj.201600912R. [Epub ahead of print]

PMID:
27836986
2.

Role of monocytes and endothelial cells in heparin-induced thrombocytopenia.

Madeeva D, Cines DB, Poncz M, Rauova L.

Thromb Haemost. 2016 Oct 28;116(5):806-812.

PMID:
27487857
3.

Platelet-specific Chemokines Contribute to the Pathogenesis of Acute Lung Injury.

Bdeir K, Gollomp K, Stasiak M, Mei J, Papiewska-Pajak I, Zhao G, Worthen GS, Cines DB, Poncz M, Kowalska MA.

Am J Respir Cell Mol Biol. 2016 Oct 18. [Epub ahead of print]

PMID:
27755915
4.

Alemtuzumab improves preexisting disability in active relapsing-remitting MS patients.

Giovannoni G, Cohen JA, Coles AJ, Hartung HP, Havrdova E, Selmaj KW, Margolin DH, Lake SL, Kaup SM, Panzara MA, Compston DA; CARE-MS II Investigators..

Neurology. 2016 Nov 8;87(19):1985-1992.

5.

Erythrocytes as Carriers for Drug Delivery in Blood Transfusion and Beyond.

Villa CH, Cines DB, Siegel DL, Muzykantov V.

Transfus Med Rev. 2016 Aug 17. pii: S0887-7963(16)30062-1. doi: 10.1016/j.tmrv.2016.08.004. [Epub ahead of print] Review.

PMID:
27707522
6.

The antigenic complex in HIT binds to B-cells via complement and complement receptor 2 (CD21).

Khandelwal S, Lee GM, Hester CG, Poncz M, McKenzie S, Sachais BS, Rauova L, Kelsoe G, Cines DB, Frank M, Arepally GM.

Blood. 2016 Jul 13. pii: blood-2016-04-709634. [Epub ahead of print]

PMID:
27412887
7.

Controversies in the treatment of immune thrombocytopenia.

Cuker A, Cines DB, Neunert CE.

Curr Opin Hematol. 2016 Sep;23(5):479-85. doi: 10.1097/MOH.0000000000000270.

PMID:
27380558
8.

Tissue-Type Plasminogen Activator-A296-299 Prevents Impairment of Cerebral Autoregulation After Stroke Through Lipoprotein-Related Receptor-Dependent Increase in cAMP and p38.

Armstead WM, Riley J, Yarovoi S, Higazi AA, Cines DB.

Stroke. 2016 Aug;47(8):2096-102. doi: 10.1161/STROKEAHA.116.012678.

PMID:
27354223
9.

Human neutrophil peptides inhibit cleavage of von Willebrand factor by ADAMTS13: a potential link of inflammation to TTP.

Pillai VG, Bao J, Zander CB, McDaniel JK, Chetty PS, Seeholzer SH, Bdeir K, Cines DB, Zheng XL.

Blood. 2016 Jul 7;128(1):110-9. doi: 10.1182/blood-2015-12-688747.

PMID:
27207796
10.

Urokinase-type Plasminogen Activator (uPA) Promotes Angiogenesis by Attenuating Proline-rich Homeodomain Protein (PRH) Transcription Factor Activity and De-repressing Vascular Endothelial Growth Factor (VEGF) Receptor Expression.

Stepanova V, Jayaraman PS, Zaitsev SV, Lebedeva T, Bdeir K, Kershaw R, Holman KR, Parfyonova YV, Semina EV, Beloglazova IB, Tkachuk VA, Cines DB.

J Biol Chem. 2016 Jul 15;291(29):15029-45. doi: 10.1074/jbc.M115.678490.

PMID:
27151212
11.

ADAMTS13 autoantibodies cloned from patients with acquired thrombotic thrombocytopenic purpura: 1. Structural and functional characterization in vitro.

Ostertag EM, Kacir S, Thiboutot M, Gulendran G, Zheng XL, Cines DB, Siegel DL.

Transfusion. 2016 Jul;56(7):1763-74. doi: 10.1111/trf.13584.

PMID:
27040144
12.

ADAMTS13 autoantibodies cloned from patients with acquired thrombotic thrombocytopenic purpura: 2. Pathogenicity in an animal model.

Ostertag EM, Bdeir K, Kacir S, Thiboutot M, Gulendran G, Yunk L, Hayes VM, Motto DG, Poncz M, Zheng XL, Cines DB, Siegel DL.

Transfusion. 2016 Jul;56(7):1775-85. doi: 10.1111/trf.13583.

PMID:
27040023
13.

Atomic features of an autoantigen in heparin-induced thrombocytopenia (HIT).

Cai Z, Zhu Z, Greene MI, Cines DB.

Autoimmun Rev. 2016 Jul;15(7):752-5. doi: 10.1016/j.autrev.2016.03.011. Review.

PMID:
26970483
14.

Platelet Factor 4 Inhibits and Enhances HIV-1 Infection in a Concentration-Dependent Manner by Modulating Viral Attachment.

Parker ZF, Rux AH, Riblett AM, Lee FH, Rauova L, Cines DB, Poncz M, Sachais BS, Doms RW.

AIDS Res Hum Retroviruses. 2016 Jul;32(7):705-17. doi: 10.1089/AID.2015.0344.

PMID:
26847431
15.

A chimeric platelet-targeted urokinase prodrug selectively blocks new thrombus formation.

Fuentes RE, Zaitsev S, Ahn HS, Hayes V, Kowalska MA, Lambert MP, Wang Y, Siegel DL, Bougie DW, Aster RH, Myers DD, Stepanova V, Cines DB, Muzykantov VR, Poncz M.

J Clin Invest. 2016 Feb;126(2):483-94.

16.

Kinetics and mechanics of clot contraction are governed by the molecular and cellular composition of the blood.

Tutwiler V, Litvinov RI, Lozhkin AP, Peshkova AD, Lebedeva T, Ataullakhanov FI, Spiller KL, Cines DB, Weisel JW.

Blood. 2016 Jan 7;127(1):149-59. doi: 10.1182/blood-2015-05-647560.

PMID:
26603837
17.

α-Defensins Induce a Post-translational Modification of Low Density Lipoprotein (LDL) That Promotes Atherosclerosis at Normal Levels of Plasma Cholesterol.

Abu-Fanne R, Maraga E, Abd-Elrahman I, Hankin A, Blum G, Abdeen S, Hijazi N, Cines DB, Higazi AA.

J Biol Chem. 2016 Feb 5;291(6):2777-86. doi: 10.1074/jbc.M115.669812.

PMID:
26518877
18.

Platelet transactivation by monocytes promotes thrombosis in heparin-induced thrombocytopenia.

Tutwiler V, Madeeva D, Ahn HS, Andrianova I, Hayes V, Zheng XL, Cines DB, McKenzie SE, Poncz M, Rauova L.

Blood. 2016 Jan 28;127(4):464-72. doi: 10.1182/blood-2013-11-539262.

PMID:
26518435
19.

Atomic description of the immune complex involved in heparin-induced thrombocytopenia.

Cai Z, Yarovoi SV, Zhu Z, Rauova L, Hayes V, Lebedeva T, Liu Q, Poncz M, Arepally G, Cines DB, Greene MI.

Nat Commun. 2015 Sep 22;6:8277. doi: 10.1038/ncomms9277.

20.

Delivery of drugs bound to erythrocytes: new avenues for an old intravascular carrier.

Villa CH, Pan DC, Zaitsev S, Cines DB, Siegel DL, Muzykantov VR.

Ther Deliv. 2015 Jul;6(7):795-826. doi: 10.4155/tde.15.34. Review.

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