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Items: 10

1.

Activation of an endothelial Notch1-Jagged1 circuit induces VCAM1 expression, an effect amplified by interleukin-1β.

Verginelli F, Adesso L, Limon I, Alisi A, Gueguen M, Panera N, Giorda E, Raimondi L, Ciarapica R, Campese AF, Screpanti I, Stifani S, Kitajewski J, Miele L, Rota R, Locatelli F.

Oncotarget. 2015 Dec 22;6(41):43216-29. doi: 10.18632/oncotarget.6456.

2.

MicroRNA-101 is repressed by EZH2 and its restoration inhibits tumorigenic features in embryonal rhabdomyosarcoma.

Vella S, Pomella S, Leoncini PP, Colletti M, Conti B, Marquez VE, Strillacci A, Roma J, Gallego S, Milano GM, Capogrossi MC, Bertaina A, Ciarapica R, Rota R.

Clin Epigenetics. 2015 Aug 6;7:82. doi: 10.1186/s13148-015-0107-z. eCollection 2015.

3.

Hyper-activation of Notch3 amplifies the proliferative potential of rhabdomyosarcoma cells.

De Salvo M, Raimondi L, Vella S, Adesso L, Ciarapica R, Verginelli F, Pannuti A, Citti A, Boldrini R, Milano GM, Cacchione A, Ferrari A, Collini P, Rosolen A, Bisogno G, Alaggio R, Inserra A, Locatelli M, Stifani S, Screpanti I, Miele L, Locatelli F, Rota R.

PLoS One. 2014 May 5;9(5):e96238. doi: 10.1371/journal.pone.0096238. eCollection 2014.

4.

Pharmacological inhibition of EZH2 as a promising differentiation therapy in embryonal RMS.

Ciarapica R, Carcarino E, Adesso L, De Salvo M, Bracaglia G, Leoncini PP, Dall'agnese A, Verginelli F, Milano GM, Boldrini R, Inserra A, Stifani S, Screpanti I, Marquez VE, Valente S, Mai A, Puri PL, Locatelli F, Palacios D, Rota R.

BMC Cancer. 2014 Feb 27;14:139. doi: 10.1186/1471-2407-14-139.

5.

MiR-21 is an Ngf-modulated microRNA that supports Ngf signaling and regulates neuronal degeneration in PC12 cells.

Montalban E, Mattugini N, Ciarapica R, Provenzano C, Savino M, Scagnoli F, Prosperini G, Carissimi C, Fulci V, Matrone C, Calissano P, Nasi S.

Neuromolecular Med. 2014 Jun;16(2):415-30. doi: 10.1007/s12017-014-8292-z. Epub 2014 Feb 4.

6.

Prolyl isomerase Pin1 and protein kinase HIPK2 cooperate to promote cortical neurogenesis by suppressing Groucho/TLE:Hes1-mediated inhibition of neuronal differentiation.

Ciarapica R, Methot L, Tang Y, Lo R, Dali R, Buscarlet M, Locatelli F, del Sal G, Rota R, Stifani S.

Cell Death Differ. 2014 Feb;21(2):321-32. doi: 10.1038/cdd.2013.160. Epub 2013 Nov 22.

7.

Notch signaling in pediatric soft tissue sarcomas.

Rota R, Ciarapica R, Miele L, Locatelli F.

BMC Med. 2012 Nov 16;10:141. doi: 10.1186/1741-7015-10-141. Review.

8.

Inhibition of Notch3 signalling induces rhabdomyosarcoma cell differentiation promoting p38 phosphorylation and p21(Cip1) expression and hampers tumour cell growth in vitro and in vivo.

Raimondi L, Ciarapica R, De Salvo M, Verginelli F, Gueguen M, Martini C, De Sio L, Cortese G, Locatelli M, Dang TP, Carlesso N, Miele L, Stifani S, Limon I, Locatelli F, Rota R.

Cell Death Differ. 2012 May;19(5):871-81. doi: 10.1038/cdd.2011.171. Epub 2011 Nov 25.

9.

MicroRNAs in rhabdomyosarcoma: pathogenetic implications and translational potentiality.

Rota R, Ciarapica R, Giordano A, Miele L, Locatelli F.

Mol Cancer. 2011 Sep 24;10:120. doi: 10.1186/1476-4598-10-120. Review.

10.

Enhancer of zeste homolog 2 (EZH2) in pediatric soft tissue sarcomas: first implications.

Ciarapica R, Miele L, Giordano A, Locatelli F, Rota R.

BMC Med. 2011 May 25;9:63. doi: 10.1186/1741-7015-9-63. Review.

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