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Items: 1 to 20 of 113

1.

The unique psychostimulant profile of (±)-modafinil: investigation of behavioral and neurochemical effects in mice.

Mereu M, Chun LE, Prisinzano TE, Newman AH, Katz JL, Tanda G.

Eur J Neurosci. 2016 Aug 22. doi: 10.1111/ejn.13376. [Epub ahead of print]

PMID:
27545285
2.

The earliest herbivorous marine reptile and its remarkable jaw apparatus.

Chun L, Rieppel O, Long C, Fraser NC.

Sci Adv. 2016 May 6;2(5):e1501659. doi: 10.1126/sciadv.1501659.

3.

Diurnal Corticosterone Presence and Phase Modulate Clock Gene Expression in the Male Rat Prefrontal Cortex.

Woodruff ER, Chun LE, Hinds LR, Spencer RL.

Endocrinology. 2016 Apr;157(4):1522-34. doi: 10.1210/en.2015-1884.

PMID:
26901093
4.

Note: Magnetic targeting for enhancement of the activation efficiency of G protein-coupled receptor with a two-pair coil system.

Cao Q, Han X, Chun L, Liu J, Li L.

Rev Sci Instrum. 2016 Jan;87(1):016103. doi: 10.1063/1.4939732.

PMID:
26827364
5.

An initial investigation into the ecology of culturable aerobic postmortem bacteria.

Chun LP, Miguel MJ, Junkins EN, Forbes SL, Carter DO.

Sci Justice. 2015 Dec;55(6):394-401. doi: 10.1016/j.scijus.2015.07.003.

PMID:
26654073
6.

Metabotropic GABA signalling modulates longevity in C. elegans.

Chun L, Gong J, Yuan F, Zhang B, Liu H, Zheng T, Yu T, Xu XZ, Liu J.

Nat Commun. 2015 Nov 5;6:8828. doi: 10.1038/ncomms9828.

7.

Identification of a Natural Viral RNA Motif That Optimizes Sensing of Viral RNA by RIG-I.

Xu J, Mercado-López X, Grier JT, Kim WK, Chun LF, Irvine EB, Del Toro Duany Y, Kell A, Hur S, Gale M Jr, Raj A, López CB.

MBio. 2015 Oct 6;6(5):e01265-15. doi: 10.1128/mBio.01265-15.

8.

Inhibition of RAF Isoforms and Active Dimers by LY3009120 Leads to Anti-tumor Activities in RAS or BRAF Mutant Cancers.

Peng SB, Henry JR, Kaufman MD, Lu WP, Smith BD, Vogeti S, Rutkoski TJ, Wise S, Chun L, Zhang Y, Van Horn RD, Yin T, Zhang X, Yadav V, Chen SH, Gong X, Ma X, Webster Y, Buchanan S, Mochalkin I, Huber L, Kays L, Donoho GP, Walgren J, McCann D, Patel P, Conti I, Plowman GD, Starling JJ, Flynn DL.

Cancer Cell. 2015 Sep 14;28(3):384-98. doi: 10.1016/j.ccell.2015.08.002.

9.

Altiratinib Inhibits Tumor Growth, Invasion, Angiogenesis, and Microenvironment-Mediated Drug Resistance via Balanced Inhibition of MET, TIE2, and VEGFR2.

Smith BD, Kaufman MD, Leary CB, Turner BA, Wise SC, Ahn YM, Booth RJ, Caldwell TM, Ensinger CL, Hood MM, Lu WP, Patt TW, Patt WC, Rutkoski TJ, Samarakoon T, Telikepalli H, Vogeti L, Vogeti S, Yates KM, Chun L, Stewart LJ, Clare M, Flynn DL.

Mol Cancer Ther. 2015 Sep;14(9):2023-34. doi: 10.1158/1535-7163.MCT-14-1105.

10.
11.

Discovery of 1-(3,3-dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl)phenyl)urea (LY3009120) as a pan-RAF inhibitor with minimal paradoxical activation and activity against BRAF or RAS mutant tumor cells.

Henry JR, Kaufman MD, Peng SB, Ahn YM, Caldwell TM, Vogeti L, Telikepalli H, Lu WP, Hood MM, Rutkoski TJ, Smith BD, Vogeti S, Miller D, Wise SC, Chun L, Zhang X, Zhang Y, Kays L, Hipskind PA, Wrobleski AD, Lobb KL, Clay JM, Cohen JD, Walgren JL, McCann D, Patel P, Clawson DK, Guo S, Manglicmot D, Groshong C, Logan C, Starling JJ, Flynn DL.

J Med Chem. 2015 May 28;58(10):4165-79. doi: 10.1021/acs.jmedchem.5b00067.

PMID:
25965804
12.

RNAi Interrogation of Dietary Modulation of Development, Metabolism, Behavior, and Aging in C. elegans.

Xiao R, Chun L, Ronan EA, Friedman DI, Liu J, Xu XZ.

Cell Rep. 2015 May 19;11(7):1123-33. doi: 10.1016/j.celrep.2015.04.024.

13.

Oxidized high-density lipoprotein accelerates atherosclerosis progression by inducing the imbalance between treg and teff in LDLR knockout mice.

Ru D, Zhiqing H, Lin Z, Feng W, Feng Z, Jiayou Z, Yusheng R, Min F, Chun L, Zonggui W.

APMIS. 2015 May;123(5):410-21. doi: 10.1111/apm.12362.

PMID:
25912129
14.

Adrenal-dependent diurnal modulation of conditioned fear extinction learning.

Woodruff ER, Greenwood BN, Chun LE, Fardi S, Hinds LR, Spencer RL.

Behav Brain Res. 2015 Jun 1;286:249-55. doi: 10.1016/j.bbr.2015.03.006.

15.

(-)-Stepholidine is a potent pan-dopamine receptor antagonist of both G protein- and β-arrestin-mediated signaling.

Meade JA, Free RB, Miller NR, Chun LS, Doyle TB, Moritz AE, Conroy JL, Watts VJ, Sibley DR.

Psychopharmacology (Berl). 2015 Mar;232(5):917-30. doi: 10.1007/s00213-014-3726-8.

PMID:
25231919
16.

Antitumor activity of miR-1280 in melanoma by regulation of Src.

Sun V, Zhou WB, Nosrati M, Majid S, Thummala S, de Semir D, Bezrookove V, de Feraudy S, Chun L, Schadendorf D, Debs R, Kashani-Sabet M, Dar AA.

Mol Ther. 2015 Jan;23(1):71-8. doi: 10.1038/mt.2014.176.

17.

Novel human D-amino acid oxidase inhibitors stabilize an active-site lid-open conformation.

Terry-Lorenzo RT, Chun LE, Brown SP, Heffernan ML, Fang QK, Orsini MA, Pollegioni L, Hardy LW, Spear KL, Large TH.

Biosci Rep. 2014 Aug 11;34(4). pii: e00133. doi: 10.1042/BSR20140071.

18.

Preference for distinct functional conformations of the dopamine transporter alters the relationship between subjective effects of cocaine and stimulation of mesolimbic dopamine.

Kohut SJ, Hiranita T, Hong SK, Ebbs AL, Tronci V, Green J, Garcés-Ramírez L, Chun LE, Mereu M, Newman AH, Katz JL, Tanda G.

Biol Psychiatry. 2014 Nov 15;76(10):802-9. doi: 10.1016/j.biopsych.2014.03.031.

19.

Discovery and characterization of a G protein-biased agonist that inhibits β-arrestin recruitment to the D2 dopamine receptor.

Free RB, Chun LS, Moritz AE, Miller BN, Doyle TB, Conroy JL, Padron A, Meade JA, Xiao J, Hu X, Dulcey AE, Han Y, Duan L, Titus S, Bryant-Genevier M, Barnaeva E, Ferrer M, Javitch JA, Beuming T, Shi L, Southall NT, Marugan JJ, Sibley DR.

Mol Pharmacol. 2014 Jul;86(1):96-105. doi: 10.1124/mol.113.090563.

20.

Screening carotid artery duplex in patients undergoing cardiac surgery.

Chun LJ, Tsai J, Tam M, Prema J, Chen LH, Patel KK.

Ann Vasc Surg. 2014 Jul;28(5):1178-85. doi: 10.1016/j.avsg.2013.07.025.

PMID:
24211602
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