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Characterization of a mouse model of sickle cell trait: parallels to human trait and a novel finding of cutaneous sensitization.

Zappia KJ, Guo Y, Retherford D, Wandersee NJ, Stucky CL, Hillery CA.

Br J Haematol. 2017 Nov;179(4):657-666. doi: 10.1111/bjh.14948. Epub 2017 Oct 12.


Determining the longitudinal validity and meaningful differences in HRQL of the PedsQLâ„¢ Sickle Cell Disease Module.

Panepinto JA, Paul Scott J, Badaki-Makun O, Darbari DS, Chumpitazi CE, Airewele GE, Ellison AM, Smith-Whitley K, Mahajan P, Sarnaik SA, Charles Casper T, Cook LJ, Leonard J, Hulbert ML, Powell EC, Liem RI, Hickey R, Krishnamurti L, Hillery CA, Brousseau DC; Pediatric Emergency Care Applied Research Network (PECARN).

Health Qual Life Outcomes. 2017 Jun 12;15(1):124. doi: 10.1186/s12955-017-0700-2.


Substance P is increased in patients with sickle cell disease and associated with haemolysis and hydroxycarbamide use.

Brandow AM, Wandersee NJ, Dasgupta M, Hoffmann RG, Hillery CA, Stucky CL, Panepinto JA.

Br J Haematol. 2016 Oct;175(2):237-245. doi: 10.1111/bjh.14300. Epub 2016 Aug 19.


R-Ras Regulates Murine T Cell Migration and Intercellular Adhesion Molecule-1 Binding.

Yan X, Yan M, Guo Y, Singh G, Chen Y, Yu M, Wang D, Hillery CA, Chan AM.

PLoS One. 2015 Dec 28;10(12):e0145218. doi: 10.1371/journal.pone.0145218. eCollection 2015.


A multicenter randomized controlled trial of intravenous magnesium for sickle cell pain crisis in children.

Brousseau DC, Scott JP, Badaki-Makun O, Darbari DS, Chumpitazi CE, Airewele GE, Ellison AM, Smith-Whitley K, Mahajan P, Sarnaik SA, Casper TC, Cook LJ, Dean JM, Leonard J, Hulbert ML, Powell EC, Liem RI, Hickey R, Krishnamurti L, Hillery CA, Nimmer M, Panepinto JA; Pediatric Emergency Care Applied Research Network (PECARN).

Blood. 2015 Oct 1;126(14):1651-7. doi: 10.1182/blood-2015-05-647107. Epub 2015 Jul 31.


Dietary supplementation with docosahexanoic acid (DHA) increases red blood cell membrane flexibility in mice with sickle cell disease.

Wandersee NJ, Maciaszek JL, Giger KM, Hanson MS, Zheng S, Guo Y, Mickelson B, Hillery CA, Lykotrafitis G, Low PS, Hogg N.

Blood Cells Mol Dis. 2015 Feb;54(2):183-8. doi: 10.1016/j.bcmd.2014.11.004. Epub 2014 Nov 25.


Sickle cell disease increases high mobility group box 1: a novel mechanism of inflammation.

Xu H, Wandersee NJ, Guo Y, Jones DW, Holzhauer SL, Hanson MS, Machogu E, Brousseau DC, Hogg N, Densmore JC, Kaul S, Hillery CA, Pritchard KA Jr.

Blood. 2014 Dec 18;124(26):3978-81. doi: 10.1182/blood-2014-04-560813. Epub 2014 Oct 22.


Cold hypersensitivity increases with age in mice with sickle cell disease.

Zappia KJ, Garrison SR, Hillery CA, Stucky CL.

Pain. 2014 Dec;155(12):2476-85. doi: 10.1016/j.pain.2014.05.030. Epub 2014 Jun 3.


Association of pro-inflammatory high-density lipoprotein cholesterol with clinical and laboratory variables in sickle cell disease.

Ataga KI, Hinderliter A, Brittain JE, Jones S, Xu H, Cai J, Kim S, Pritchard KA, Hillery CA.

Hematology. 2015 Jun;20(5):289-96. doi: 10.1179/1607845414Y.0000000171. Epub 2014 May 6.


Circulating membrane-derived microvesicles in redox biology.

Larson MC, Hillery CA, Hogg N.

Free Radic Biol Med. 2014 Aug;73:214-28. doi: 10.1016/j.freeradbiomed.2014.04.017. Epub 2014 Apr 18. Review.


Anion exchange HPLC isolation of high-density lipoprotein (HDL) and on-line estimation of proinflammatory HDL.

Ji X, Xu H, Zhang H, Hillery CA, Gao HQ, Pritchard KA Jr.

PLoS One. 2014 Mar 7;9(3):e91089. doi: 10.1371/journal.pone.0091089. eCollection 2014.


Intravenous magnesium for pediatric sickle cell vaso-occlusive crisis: methodological issues of a randomized controlled trial.

Badaki-Makun O, Scott JP, Panepinto JA, Casper TC, Hillery CA, Dean JM, Brousseau DC; Pediatric Emergency Care Applied Research Network (PECARN) Magnesium in Sickle Cell Crisis (MAGiC) Study Group.

Pediatr Blood Cancer. 2014 Jun;61(6):1049-54. doi: 10.1002/pbc.24925. Epub 2014 Jan 17.


Inhibition of myeloperoxidase decreases vascular oxidative stress and increases vasodilatation in sickle cell disease mice.

Zhang H, Xu H, Weihrauch D, Jones DW, Jing X, Shi Y, Gourlay D, Oldham KT, Hillery CA, Pritchard KA Jr.

J Lipid Res. 2013 Nov;54(11):3009-15. doi: 10.1194/jlr.M038281. Epub 2013 Aug 16.


N-acetyl lysyltyrosylcysteine amide inhibits myeloperoxidase, a novel tripeptide inhibitor.

Zhang H, Jing X, Shi Y, Xu H, Du J, Guan T, Weihrauch D, Jones DW, Wang W, Gourlay D, Oldham KT, Hillery CA, Pritchard KA Jr.

J Lipid Res. 2013 Nov;54(11):3016-29. doi: 10.1194/jlr.M038273. Epub 2013 Jul 24.


A novel hemoglobin-binding peptide reduces cell-free hemoglobin in murine hemolytic anemia.

Hanson MS, Xu H, Flewelen TC, Holzhauer SL, Retherford D, Jones DW, Frei AC, Pritchard KA Jr, Hillery CA, Hogg N, Wandersee NJ.

Am J Physiol Heart Circ Physiol. 2013 Jan 15;304(2):H328-36. doi: 10.1152/ajpheart.00500.2012. Epub 2012 Nov 2.


Calcium-phosphate microprecipitates mimic microparticles when examined with flow cytometry.

Larson MC, Luthi MR, Hogg N, Hillery CA.

Cytometry A. 2013 Feb;83(2):242-50. doi: 10.1002/cyto.a.22222. Epub 2012 Nov 2.


Patients with sickle cell disease have increased sensitivity to cold and heat.

Brandow AM, Stucky CL, Hillery CA, Hoffmann RG, Panepinto JA.

Am J Hematol. 2013 Jan;88(1):37-43. doi: 10.1002/ajh.23341. Epub 2012 Oct 31.


Sickle cell mice exhibit mechanical allodynia and enhanced responsiveness in light touch cutaneous mechanoreceptors.

Garrison SR, Kramer AA, Gerges NZ, Hillery CA, Stucky CL.

Mol Pain. 2012 Sep 10;8:62. doi: 10.1186/1744-8069-8-62.


Phosphatidylethanolamine is externalized at the surface of microparticles.

Larson MC, Woodliff JE, Hillery CA, Kearl TJ, Zhao M.

Biochim Biophys Acta. 2012 Dec;1821(12):1501-7. doi: 10.1016/j.bbalip.2012.08.017. Epub 2012 Aug 30.


Effects of experimental asthma on inflammation and lung mechanics in sickle cell mice.

Pritchard KA Jr, Feroah TR, Nandedkar SD, Holzhauer SL, Hutchins W, Schulte ML, Strunk RC, Debaun MR, Hillery CA.

Am J Respir Cell Mol Biol. 2012 Mar;46(3):389-96. doi: 10.1165/rcmb.2011-0097OC. Epub 2011 Oct 27.

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