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Items: 1 to 20 of 142

1.

Synthesis of the novel PARP-1 inhibitor AG-690/11026014 and its protective effects on angiotensin II-induced mouse cardiac remodeling.

Feng GS, Zhu CG, Li ZM, Wang PX, Huang Y, Liu M, He P, Lou LL, Chen SR, Liu PQ.

Acta Pharmacol Sin. 2017 May;38(5):638-650. doi: 10.1038/aps.2016.159. Epub 2017 Feb 27.

2.

The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+ Binding but Not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor.

Søndergaard MT, Liu Y, Larsen KT, Nani A, Tian X, Holt C, Wang R, Wimmer R, Van Petegem F, Fill M, Chen SR, Overgaard MT.

J Biol Chem. 2017 Jan 27;292(4):1385-1395. doi: 10.1074/jbc.M116.766253. Epub 2016 Dec 7.

3.

The control of male fertility by spermatid-specific factors: searching for contraceptive targets from spermatozoon's head to tail.

Chen SR, Batool A, Wang YQ, Hao XX, Chang CS, Cheng CY, Liu YX.

Cell Death Dis. 2016 Nov 10;7(11):e2472. doi: 10.1038/cddis.2016.344. Review.

4.

Pre-clinical characterization of PKC412, a multi-kinase inhibitor, against colorectal cancer cells.

Li JP, Huang ZJ, Lu XS, Zhou YC, Shao Y, He XP, Chen SR, Wang DD, Qin LS, Sun WH.

Oncotarget. 2016 Nov 22;7(47):77815-77824. doi: 10.18632/oncotarget.12802.

5.

Tylophorine Analog DCB-3503 Inhibited Cyclin D1 Translation through Allosteric Regulation of Heat Shock Cognate Protein 70.

Wang Y, Lam W, Chen SR, Guan FL, Dutchman GE, Francis S, Baker DC, Cheng YC.

Sci Rep. 2016 Sep 6;6:32832. doi: 10.1038/srep32832.

6.

Anti-Dengue Virus Constituents from Formosan Zoanthid Palythoa mutuki.

Lee JC, Chang FR, Chen SR, Wu YH, Hu HC, Wu YC, Backlund A, Cheng YB.

Mar Drugs. 2016 Aug 9;14(8). pii: E151. doi: 10.3390/md14080151.

7.

BTG1 might be employed as a biomarker for carcinogenesis and a target for gene therapy in colorectal cancers.

Zhao S, Chen SR, Yang XF, Shen DF, Takano Y, Su RJ, Zheng HC.

Oncotarget. 2017 Jan 31;8(5):7502-7520. doi: 10.18632/oncotarget.10649.

8.

Does murine spermatogenesis require WNT signalling? A lesson from Gpr177 conditional knockout mouse models.

Chen SR, Tang JX, Cheng JM, Hao XX, Wang YQ, Wang XX, Liu YX.

Cell Death Dis. 2016 Jun 30;7(6):e2281. doi: 10.1038/cddis.2016.191.

9.

Methylprednisolone exerts neuroprotective effects by regulating autophagy and apoptosis.

Gao W, Chen SR, Wu MY, Gao K, Li YL, Wang HY, Li CY, Li H.

Neural Regen Res. 2016 May;11(5):823-8. doi: 10.4103/1673-5374.182711.

10.

Chloride Homeostasis Critically Regulates Synaptic NMDA Receptor Activity in Neuropathic Pain.

Li L, Chen SR, Chen H, Wen L, Hittelman WN, Xie JD, Pan HL.

Cell Rep. 2016 May 17;15(7):1376-83. doi: 10.1016/j.celrep.2016.04.039. Epub 2016 May 5.

11.

Myh11-Cre is not limited to peritubular myoid cells and interaction between Sertoli and peritubular myoid cells needs investigation.

Chen SR, Liu YX.

Proc Natl Acad Sci U S A. 2016 Apr 26;113(17):E2352. doi: 10.1073/pnas.1602873113. Epub 2016 Apr 1. No abstract available.

12.

Sodium-hydrogen exchanger NHA1 and NHA2 control sperm motility and male fertility.

Chen SR, Chen M, Deng SL, Hao XX, Wang XX, Liu YX.

Cell Death Dis. 2016 Mar 24;7:e2152. doi: 10.1038/cddis.2016.65.

13.

The association between S100A13 and HMGA1 in the modulation of thyroid cancer proliferation and invasion.

Zhong J, Liu C, Chen YJ, Zhang QH, Yang J, Kang X, Chen SR, Wen GB, Zu XY, Cao RX.

J Transl Med. 2016 Mar 23;14:80. doi: 10.1186/s12967-016-0824-x.

14.

Androgen receptor in Sertoli cells regulates DNA double-strand break repair and chromosomal synapsis of spermatocytes partially through intercellular EGF-EGFR signaling.

Chen SR, Hao XX, Zhang Y, Deng SL, Wang ZP, Wang YQ, Wang XX, Liu YX.

Oncotarget. 2016 Apr 5;7(14):18722-35. doi: 10.18632/oncotarget.7916.

15.

Nerve Injury Diminishes Opioid Analgesia through Lysine Methyltransferase-mediated Transcriptional Repression of μ-Opioid Receptors in Primary Sensory Neurons.

Zhang Y, Chen SR, Laumet G, Chen H, Pan HL.

J Biol Chem. 2016 Apr 15;291(16):8475-85. doi: 10.1074/jbc.M115.711812. Epub 2016 Feb 25.

16.

Muscarinic receptor subtypes differentially control synaptic input and excitability of cerebellum-projecting medial vestibular nucleus neurons.

Zhu Y, Chen SR, Pan HL.

J Neurochem. 2016 Apr;137(2):226-39. doi: 10.1111/jnc.13554. Epub 2016 Feb 15.

17.

The EF-hand Ca2+ Binding Domain Is Not Required for Cytosolic Ca2+ Activation of the Cardiac Ryanodine Receptor.

Guo W, Sun B, Xiao Z, Liu Y, Wang Y, Zhang L, Wang R, Chen SR.

J Biol Chem. 2016 Jan 29;291(5):2150-60. doi: 10.1074/jbc.M115.693325. Epub 2015 Dec 9.

18.

G9a is essential for epigenetic silencing of K(+) channel genes in acute-to-chronic pain transition.

Laumet G, Garriga J, Chen SR, Zhang Y, Li DP, Smith TM, Dong Y, Jelinek J, Cesaroni M, Issa JP, Pan HL.

Nat Neurosci. 2015 Dec;18(12):1746-55. doi: 10.1038/nn.4165. Epub 2015 Nov 9.

19.

Loss of Gata4 in Sertoli cells impairs the spermatogonial stem cell niche and causes germ cell exhaustion by attenuating chemokine signaling.

Chen SR, Tang JX, Cheng JM, Li J, Jin C, Li XY, Deng SL, Zhang Y, Wang XX, Liu YX.

Oncotarget. 2015 Nov 10;6(35):37012-27. doi: 10.18632/oncotarget.6115.

20.

The H29D Mutation Does Not Enhance Cytosolic Ca2+ Activation of the Cardiac Ryanodine Receptor.

Xiao Z, Guo W, Yuen SM, Wang R, Zhang L, Van Petegem F, Chen SR.

PLoS One. 2015 Sep 25;10(9):e0139058. doi: 10.1371/journal.pone.0139058. eCollection 2015.

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