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From Benchtop to Bedside: A Review of Oncolytic Virotherapy.

Choi AH, O'Leary MP, Fong Y, Chen NG.

Biomedicines. 2016 Aug 2;4(3). pii: E18. doi: 10.3390/biomedicines4030018. Review.


Recent Advances in Anticancer Activities and Drug Delivery Systems of Tannins.

Cai Y, Zhang J, Chen NG, Shi Z, Qiu J, He C, Chen M.

Med Res Rev. 2017 Jul;37(4):665-701. doi: 10.1002/med.21422. Epub 2016 Dec 22. Review.


Selective killing of cancer cells by nanoparticle-assisted ultrasound.

Kosheleva OK, Lai TC, Chen NG, Hsiao M, Chen CH.

J Nanobiotechnology. 2016 Jun 14;14(1):46. doi: 10.1186/s12951-016-0194-9.


Uniqueness: skews bit occurrence frequencies in randomly generated fingerprint libraries.

Chen NG.

Mol Divers. 2016 Aug;20(3):741-5. doi: 10.1007/s11030-016-9674-y. Epub 2016 May 26.


Molecular network, pathway, and functional analysis of time-dependent gene changes associated with pancreatic cancer susceptibility to oncolytic vaccinia virotherapy.

Haddad D, Socci N, Chen CH, Chen NG, Zhang Q, Carpenter SG, Mittra A, Szalay AA, Fong Y.

Mol Ther Oncolytics. 2016 Mar 16;3:16008. doi: 10.1038/mto.2016.8. eCollection 2016.


Erratum to: A novel vaccinia virus with dual oncolytic and anti-angiogenic therapeutic effects against triple-negative breast cancer.

Gholami S, Marano A, Chen NG, Aguilar RJ, Frentzen A, Chen CH, Lou E, Fujisawa S, Eveno C, Belin L, Zanzonico P, Szalay A, Fong Y.

Breast Cancer Res Treat. 2016 Apr;156(3):607-608. doi: 10.1007/s10549-016-3767-2. No abstract available.


Recombinant vaccinia virus GLV-1h68 is a promising oncolytic vector in the treatment of cholangiocarcinoma.

Pugalenthi A, Mojica K, Ady JW, Johnsen C, Love D, Chen NG, Aguilar RJ, Szalay AA, Fong Y.

Cancer Gene Ther. 2015 Dec;22(12):591-6. doi: 10.1038/cgt.2015.60. Epub 2015 Nov 20.


Microglia and astrocytes attenuate the replication of the oncolytic vaccinia virus LIVP 1.1.1 in murine GL261 gliomas by acting as vaccinia virus traps.

Kober C, Rohn S, Weibel S, Geissinger U, Chen NG, Szalay AA.

J Transl Med. 2015 Jul 7;13:216. doi: 10.1186/s12967-015-0586-x.


Oncolytic gene therapy with recombinant vaccinia strain GLV-2b372 efficiently kills hepatocellular carcinoma.

Ady JW, Johnsen C, Mojica K, Heffner J, Love D, Pugalenthi A, Belin LJ, Chen NG, Yu YA, Szalay AA, Fong Y.

Surgery. 2015 Aug;158(2):331-8. doi: 10.1016/j.surg.2015.03.044. Epub 2015 Jun 3.


Expression of anti-VEGF antibody together with anti-EGFR or anti-FAP enhances tumor regression as a result of vaccinia virotherapy.

Huang T, Wang H, Chen NG, Frentzen A, Minev B, Szalay AA.

Mol Ther Oncolytics. 2015 Mar 18;2:15003. doi: 10.1038/mto.2015.3. eCollection 2015.


A novel vaccinia virus with dual oncolytic and anti-angiogenic therapeutic effects against triple-negative breast cancer.

Gholami S, Marano A, Chen NG, Aguilar RJ, Frentzen A, Chen CH, Lou E, Fujisawa S, Eveno C, Belin L, Zanzonico P, Szalay A, Fong Y.

Breast Cancer Res Treat. 2014 Dec;148(3):489-99. doi: 10.1007/s10549-014-3180-7. Epub 2014 Nov 13. Erratum in: Breast Cancer Res Treat. 2016 Apr;156(3):607-8.


Silk-elastin-like protein polymer matrix for intraoperative delivery of an oncolytic vaccinia virus.

Price DL, Li P, Chen CH, Wong D, Yu Z, Chen NG, Yu YA, Szalay AA, Cappello J, Fong Y, Wong RJ.

Head Neck. 2016 Feb;38(2):237-46. doi: 10.1002/hed.23877. Epub 2015 Jun 16.


Evaluation of a new recombinant oncolytic vaccinia virus strain GLV-5b451 for feline mammary carcinoma therapy.

Adelfinger M, Gentschev I, Grimm de Guibert J, Weibel S, Langbein-Laugwitz J, Härtl B, Murua Escobar H, Nolte I, Chen NG, Aguilar RJ, Yu YA, Zhang Q, Frentzen A, Szalay AA.

PLoS One. 2014 Aug 5;9(8):e104337. doi: 10.1371/journal.pone.0104337. eCollection 2014.


Differentiation of neural stem/progenitor cells using low-intensity ultrasound.

Lee IC, Lo TL, Young TH, Li YC, Chen NG, Chen CH, Chang YC.

Ultrasound Med Biol. 2014 Sep;40(9):2195-206. doi: 10.1016/j.ultrasmedbio.2014.05.001. Epub 2014 Jul 9.


Isolated limb perfusion with melphalan, tumour necrosis factor-alpha and oncolytic vaccinia virus improves tumour targeting and prolongs survival in a rat model of advanced extremity sarcoma.

Pencavel TD, Wilkinson MJ, Mansfield DC, Khan AA, Seth R, Karapanagiotou EM, Roulstone V, Aguilar RJ, Chen NG, Szalay AA, Hayes AJ, Harrington KJ.

Int J Cancer. 2015 Feb 15;136(4):965-76. doi: 10.1002/ijc.29059. Epub 2014 Jul 22.


Oncolytic immunotherapy using recombinant vaccinia virus GLV-1h68 kills sorafenib-resistant hepatocellular carcinoma efficiently.

Ady JW, Heffner J, Mojica K, Johnsen C, Belin LJ, Love D, Chen CT, Pugalenthi A, Klein E, Chen NG, Yu YA, Szalay AA, Fong Y.

Surgery. 2014 Aug;156(2):263-9. doi: 10.1016/j.surg.2014.03.031. Epub 2014 Jun 21.


Characterization of metastasis formation and virotherapy in the human C33A cervical cancer model.

Donat U, Rother J, Schäfer S, Hess M, Härtl B, Kober C, Langbein-Laugwitz J, Stritzker J, Chen NG, Aguilar RJ, Weibel S, Szalay AA.

PLoS One. 2014 Jun 2;9(6):e98533. doi: 10.1371/journal.pone.0098533. eCollection 2014.


Biotherapeutic approaches to target cancer stem cells.

Duggal R, Minev B, Geissinger U, Wang H, Chen NG, Koka PS, Szalay AA.

J Stem Cells. 2013;8(3-4):135-49. doi: jsc.2014.8.3/4.135. Review.


[Development and assessment of Schistosoma japonicum antibody test kit (IHA)].

Jiang WS, Chen NG, Huang MJ, Lan WM, Xie SY, Wu J, Zeng XJ, Lin DD.

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2013 Dec;25(6):594-7. Chinese.


A novel oncolytic viral therapy and imaging technique for gastric cancer using a genetically engineered vaccinia virus carrying the human sodium iodide symporter.

Jun KH, Gholami S, Song TJ, Au J, Haddad D, Carson J, Chen CH, Mojica K, Zanzonico P, Chen NG, Zhang Q, Szalay A, Fong Y.

J Exp Clin Cancer Res. 2014 Jan 2;33:2. doi: 10.1186/1756-9966-33-2.

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