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Items: 1 to 20 of 91


Differentiation of Club Cells to Alveolar Epithelial Cells In Vitro.

Zheng D, Soh BS, Yin L, Hu G, Chen Q, Choi H, Han J, Chow VT, Chen J.

Sci Rep. 2017 Jan 27;7:41661. doi: 10.1038/srep41661.


Interleukins 7 and 15 Maintain Human T Cell Proliferative Capacity through STAT5 Signaling.

Drake A, Kaur M, Iliopoulou BP, Phennicie R, Hanson A, Chen J.

PLoS One. 2016 Nov 17;11(11):e0166280. doi: 10.1371/journal.pone.0166280. eCollection 2016.


Targeting Epstein-Barr virus-transformed B lymphoblastoid cells using antibodies with T-cell receptor-like specificities.

Lai J, Tan WJ, Too CT, Choo JA, Wong LH, Mustafa FB, Srinivasan N, Lim AP, Zhong Y, Gascoigne NR, Hanson BJ, Chan SH, Chen J, MacAry PA.

Blood. 2016 Sep 8;128(10):1396-407. doi: 10.1182/blood-2016-03-707836. Epub 2016 Jun 23.


Delineation of Natural Killer Cell Differentiation from Myeloid Progenitors in Human.

Chen Q, Ye W, Jian Tan W, Mei Yong KS, Liu M, Qi Tan S, Loh E, Te Chang K, Chye Tan T, Preiser PR, Chen J.

Sci Rep. 2015 Oct 12;5:15118. doi: 10.1038/srep15118.


Basigin is a druggable target for host-oriented antimalarial interventions.

Zenonos ZA, Dummler SK, Müller-Sienerth N, Chen J, Preiser PR, Rayner JC, Wright GJ.

J Exp Med. 2015 Jul 27;212(8):1145-51. doi: 10.1084/jem.20150032. Epub 2015 Jul 20.


Structure-Guided Design of an Anti-dengue Antibody Directed to a Non-immunodominant Epitope.

Robinson LN, Tharakaraman K, Rowley KJ, Costa VV, Chan KR, Wong YH, Ong LC, Tan HC, Koch T, Cain D, Kirloskar R, Viswanathan K, Liew CW, Tissire H, Ramakrishnan B, Myette JR, Babcock GJ, Sasisekharan V, Alonso S, Chen J, Lescar J, Shriver Z, Ooi EE, Sasisekharan R.

Cell. 2015 Jul 30;162(3):493-504. doi: 10.1016/j.cell.2015.06.057. Epub 2015 Jul 16.


Persistent Antigen and Prolonged AKT-mTORC1 Activation Underlie Memory CD8 T Cell Impairment in the Absence of CD4 T Cells.

Li Y, Shen C, Zhu B, Shi F, Eisen HN, Chen J.

J Immunol. 2015 Aug 15;195(4):1591-8. doi: 10.4049/jimmunol.1500451. Epub 2015 Jul 10.


Characterisation of liver pathogenesis, human immune responses and drug testing in a humanised mouse model of HCV infection.

Keng CT, Sze CW, Zheng D, Zheng Z, Yong KS, Tan SQ, Ong JJ, Tan SY, Loh E, Upadya MH, Kuick CH, Hotta H, Lim SG, Tan TC, Chang KT, Hong W, Chen J, Tan YJ, Chen Q.

Gut. 2016 Oct;65(10):1744-53. doi: 10.1136/gutjnl-2014-307856. Epub 2015 Jul 6.


De Novo Generated Human Red Blood Cells in Humanized Mice Support Plasmodium falciparum Infection.

Amaladoss A, Chen Q, Liu M, Dummler SK, Dao M, Suresh S, Chen J, Preiser PR.

PLoS One. 2015 Jun 22;10(6):e0129825. doi: 10.1371/journal.pone.0129825. eCollection 2015.


Multi-Stage Tuberculosis Subunit Vaccine Candidate LT69 Provides High Protection against Mycobacterium tuberculosis Infection in Mice.

Niu H, Peng J, Bai C, Liu X, Hu L, Luo Y, Wang B, Zhang Y, Chen J, Yu H, Xian Q, Zhu B.

PLoS One. 2015 Jun 22;10(6):e0130641. doi: 10.1371/journal.pone.0130641. eCollection 2015.


SCARB2/LIMP-2 Regulates IFN Production of Plasmacytoid Dendritic Cells by Mediating Endosomal Translocation of TLR9 and Nuclear Translocation of IRF7.

Guo H, Zhang J, Zhang X, Wang Y, Yu H, Yin X, Li J, Du P, Plumas J, Chaperot L, Chen J, Su L, Liu Y, Zhang L.

J Immunol. 2015 May 15;194(10):4737-49. doi: 10.4049/jimmunol.1402312. Epub 2015 Apr 10.


Aging exacerbates damage and delays repair of alveolar epithelia following influenza viral pneumonia.

Yin L, Zheng D, Limmon GV, Leung NH, Xu S, Rajapakse JC, Yu H, Chow VT, Chen J.

Respir Res. 2014 Sep 30;15:116. doi: 10.1186/s12931-014-0116-z.


Long-term reproducible expression in human fetal liver hematopoietic stem cells with a UCOE-based lentiviral vector.

Dighe N, Khoury M, Mattar C, Chong M, Choolani M, Chen J, Antoniou MN, Chan JK.

PLoS One. 2014 Aug 12;9(8):e104805. doi: 10.1371/journal.pone.0104805. eCollection 2014.


CD8+ T-cell responses rapidly select for antigen-negative tumor cells in the prostate.

Bak SP, Barnkob MS, Wittrup KD, Chen J.

Cancer Immunol Res. 2013 Dec;1(6):393-401. doi: 10.1158/2326-6066.CIR-13-0109. Epub 2013 Sep 20.


Molecular analysis of serum and bronchoalveolar lavage in a mouse model of influenza reveals markers of disease severity that can be clinically useful in humans.

Kumar Y, Liang C, Limmon GV, Liang L, Engelward BP, Ooi EE, Chen J, Tannenbaum SR.

PLoS One. 2014 Feb 5;9(2):e86912. doi: 10.1371/journal.pone.0086912. eCollection 2014.


Sensitizing protective tumor microenvironments to antibody-mediated therapy.

Pallasch CP, Leskov I, Braun CJ, Vorholt D, Drake A, Soto-Feliciano YM, Bent EH, Schwamb J, Iliopoulou B, Kutsch N, van Rooijen N, Frenzel LP, Wendtner CM, Heukamp L, Kreuzer KA, Hallek M, Chen J, Hemann MT.

Cell. 2014 Jan 30;156(3):590-602. doi: 10.1016/j.cell.2013.12.041.


Human natural killer cells control Plasmodium falciparum infection by eliminating infected red blood cells.

Chen Q, Amaladoss A, Ye W, Liu M, Dummler S, Kong F, Wong LH, Loo HL, Loh E, Tan SQ, Tan TC, Chang KT, Dao M, Suresh S, Preiser PR, Chen J.

Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1479-84. doi: 10.1073/pnas.1323318111. Epub 2014 Jan 13.


Defining the expression hierarchy of latent T-cell epitopes in Epstein-Barr virus infection with TCR-like antibodies.

Sim AC, Too CT, Oo MZ, Lai J, Eio MY, Song Z, Srinivasan N, Tan DA, Pang SW, Gan SU, Lee KO, Loh TK, Chen J, Chan SH, MacAry PA.

Sci Rep. 2013 Nov 18;3:3232. doi: 10.1038/srep03232.


Zanamivir conjugated to poly-L-glutamine is much more active against influenza viruses in mice and ferrets than the drug itself.

Weight AK, Belser JA, Tumpey TM, Chen J, Klibanov AM.

Pharm Res. 2014 Feb;31(2):466-74. doi: 10.1007/s11095-013-1175-4. Epub 2013 Sep 25.

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