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Items: 8


Activation of Rho Family GTPases by Small Molecules.

Palsuledesai CC, Surviladze Z, Waller A, Miscioscia TF, Guo Y, Wu Y, Strouse J, Romero E, Salas VM, Curpan R, Young S, Carter M, Foutz T, Galochkina Z, Ames H, Haynes MK, Edwards BS, Nicolotti O, Luo L, Ursu O, Bologa CG, Oprea TI, Wandinger-Ness A, Sklar LA.

ACS Chem Biol. 2018 Jun 15;13(6):1514-1524. doi: 10.1021/acschembio.8b00038. Epub 2018 May 24.


Global proteomic analysis of prenylated proteins in Plasmodium falciparum using an alkyne-modified isoprenoid analogue.

Suazo KF, Schaber C, Palsuledesai CC, Odom John AR, Distefano MD.

Sci Rep. 2016 Dec 7;6:38615. doi: 10.1038/srep38615.


Metabolic Labeling with an Alkyne-modified Isoprenoid Analog Facilitates Imaging and Quantification of the Prenylome in Cells.

Palsuledesai CC, Ochocki JD, Kuhns MM, Wang YC, Warmka JK, Chernick DS, Wattenberg EV, Li L, Arriaga EA, Distefano MD.

ACS Chem Biol. 2016 Oct 21;11(10):2820-2828. Epub 2016 Aug 31.


Nitrodibenzofuran: A One- and Two-Photon Sensitive Protecting Group That Is Superior to Brominated Hydroxycoumarin for Thiol Caging in Peptides.

Mahmoodi MM, Abate-Pella D, Pundsack TJ, Palsuledesai CC, Goff PC, Blank DA, Distefano MD.

J Am Chem Soc. 2016 May 11;138(18):5848-59. doi: 10.1021/jacs.5b11759. Epub 2016 May 2.


Protein prenylation: enzymes, therapeutics, and biotechnology applications.

Palsuledesai CC, Distefano MD.

ACS Chem Biol. 2015 Jan 16;10(1):51-62. doi: 10.1021/cb500791f. Epub 2014 Dec 8. Review.


A combination of metabolic labeling and 2D-DIGE analysis in response to a farnesyltransferase inhibitor facilitates the discovery of new prenylated proteins.

Palsuledesai CC, Ochocki JD, Markowski TW, Distefano MD.

Mol Biosyst. 2014 May;10(5):1094-103. doi: 10.1039/c3mb70593e.


Evaluation of alkyne-modified isoprenoids as chemical reporters of protein prenylation.

DeGraw AJ, Palsuledesai C, Ochocki JD, Dozier JK, Lenevich S, Rashidian M, Distefano MD.

Chem Biol Drug Des. 2010 Dec;76(6):460-71. doi: 10.1111/j.1747-0285.2010.01037.x. Epub 2010 Oct 11.


Acyl-isothiocyanates as efficient thiocyanate transfer reagents.

Palsuledesai CC, Murru S, Sahoo SK, Patel BK.

Org Lett. 2009 Aug 6;11(15):3382-5. doi: 10.1021/ol901561j.


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