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Items: 1 to 20 of 235


Proteomic profiling of the hypothalamus in two mouse models of narcolepsy.

Azzam S, Schlatzer D, Nethery D, Saleh D, Li X, Akladious A, Chance MR, Strohl KP.

Proteomics. 2017 May 22. doi: 10.1002/pmic.201600478. [Epub ahead of print]


Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth.

Sangodkar J, Perl A, Tohme R, Kiselar J, Kastrinsky DB, Zaware N, Izadmehr S, Mazhar S, Wiredja DD, O'Connor CM, Hoon D, Dhawan NS, Schlatzer D, Yao S, Leonard D, Borczuk AC, Gokulrangan G, Wang L, Svenson E, Farrington CC, Yuan E, Avelar RA, Stachnik A, Smith B, Gidwani V, Giannini HM, McQuaid D, McClinch K, Wang Z, Levine AC, Sears RC, Chen EY, Duan Q, Datt M, Haider S, Ma'ayan A, DiFeo A, Sharma N, Galsky MD, Brautigan DL, Ioannou YA, Xu W, Chance MR, Ohlmeyer M, Narla G.

J Clin Invest. 2017 Jun 1;127(6):2081-2090. doi: 10.1172/JCI89548. Epub 2017 May 15.


A Targeted Mass Spectrometry Assay for Detection of HIV Gag Protein Following Induction of Latent Viral Reservoirs.

Schlatzer D, Haqqani AA, Li X, Dobrowolski C, Chance MR, Tilton JC.

Anal Chem. 2017 May 16;89(10):5325-5332. doi: 10.1021/acs.analchem.6b05070. Epub 2017 May 3.


Linearity of network proximity measures: implications for set-based queries and significance testing.

Maxwell S, Chance MR, Koyutürk M.

Bioinformatics. 2017 May 1;33(9):1354-1361. doi: 10.1093/bioinformatics/btw733.


Proteome and Protein Network Analyses of Memory T Cells Find Altered Translation and Cell Stress Signaling in Treated Human Immunodeficiency Virus Patients Exhibiting Poor CD4 Recovery.

Azzam S, Schlatzer D, Maxwell S, Li X, Bazdar D, Chen Y, Asaad R, Barnholtz-Sloan J, Chance MR, Sieg SF.

Open Forum Infect Dis. 2016 Mar 15;3(2):ofw037. doi: 10.1093/ofid/ofw037. eCollection 2016 Mar.


Protein Footprinting Comes of Age: Mass Spectrometry for Biophysical Structure Assessment.

Wang L, Chance MR.

Mol Cell Proteomics. 2017 May;16(5):706-716. doi: 10.1074/mcp.O116.064386. Epub 2017 Mar 8. Review.


Structural basis of ligand interaction with atypical chemokine receptor 3.

Gustavsson M, Wang L, van Gils N, Stephens BS, Zhang P, Schall TJ, Yang S, Abagyan R, Chance MR, Kufareva I, Handel TM.

Nat Commun. 2017 Jan 18;8:14135. doi: 10.1038/ncomms14135.


Linearity of Network Proximity Measures: Implications for Set-based Queries and Significance Testing.

Maxwell S, Chance MR, Koyutürk M.

Bioinformatics. 2016 Dec 19. pii: btw733. doi: 10.1093/bioinformatics/btw733. [Epub ahead of print]


Finding lost genes in GWAS via integrative-omics analysis reveals novel sub-networks associated with preterm birth.

Brubaker D, Liu Y, Wang J, Tan H, Zhang G, Jacobsson B, Muglia L, Mesiano S, Chance MR.

Hum Mol Genet. 2016 Dec 1;25(23):5254-5264. doi: 10.1093/hmg/ddw325.


During Hepatitis C Virus (HCV) Infection and HCV-HIV Coinfection, an Elevated Plasma Level of Autotaxin Is Associated With Lysophosphatidic Acid and Markers of Immune Activation That Normalize During Interferon-Free HCV Therapy.

Kostadinova L, Shive CL, Judge C, Zebrowski E, Compan A, Rife K, Hirsch A, Falck-Ytter Y, Schlatzer DM, Li X, Chance MR, Rodriguez B, Popkin DL, Anthony DD.

J Infect Dis. 2016 Nov 1;214(9):1438-1448. Epub 2016 Aug 17.


Probing the structure of ribosome assembly intermediates in vivo using DMS and hydroxyl radical footprinting.

Hulscher RM, Bohon J, Rappé MC, Gupta S, D'Mello R, Sullivan M, Ralston CY, Chance MR, Woodson SA.

Methods. 2016 Jul 1;103:49-56. doi: 10.1016/j.ymeth.2016.03.012. Epub 2016 Mar 22.


Apigenin blocks IKKα activation and suppresses prostate cancer progression.

Shukla S, Kanwal R, Shankar E, Datt M, Chance MR, Fu P, MacLennan GT, Gupta S.

Oncotarget. 2015 Oct 13;6(31):31216-32. doi: 10.18632/oncotarget.5157.


Proteomic and bioinformatics profile of paired human alveolar macrophages and peripheral blood monocytes.

Tomechko SE, Lundberg KC, Jarvela J, Bebek G, Chesnokov NG, Schlatzer D, Ewing RM, Boom WH, Chance MR, Silver RF.

Proteomics. 2015 Nov;15(22):3797-805. doi: 10.1002/pmic.201400496.


MOBAS: identification of disease-associated protein subnetworks using modularity-based scoring.

Ayati M, Erten S, Chance MR, Koyutürk M.

EURASIP J Bioinform Syst Biol. 2015 Jun 30;2015:7. doi: 10.1186/s13637-015-0025-6. eCollection 2015 Dec.


Characterizing monoclonal antibody structure by carboxyl group footprinting.

Kaur P, Tomechko SE, Kiselar J, Shi W, Deperalta G, Wecksler AT, Gokulrangan G, Ling V, Chance MR.

MAbs. 2015;7(3):540-52. doi: 10.1080/19420862.2015.1023683.


Phosphorylation of HEXIM1 at Tyr271 and Tyr274 Promotes Release of P-TEFb from the 7SK snRNP Complex and Enhances Proviral HIV Gene Expression.

Mbonye UR, Wang B, Gokulrangan G, Chance MR, Karn J.

Proteomics. 2015 Jun;15(12):2078-86. doi: 10.1002/pmic.201500038. Epub 2015 May 15. Erratum in: Proteomics. 2016 Aug;16(15-16):2302.


Detection of structural waters and their role in structural dynamics of rhodopsin activation.

Wang L, Chance MR.

Methods Mol Biol. 2015;1271:97-111. doi: 10.1007/978-1-4939-2330-4_7.


Quantitative protein topography analysis and high-resolution structure prediction using hydroxyl radical labeling and tandem-ion mass spectrometry (MS).

Kaur P, Kiselar J, Yang S, Chance MR.

Mol Cell Proteomics. 2015 Apr;14(4):1159-68. doi: 10.1074/mcp.O114.044362. Epub 2015 Feb 16.


Acetyl-L-carnitine increases mitochondrial protein acetylation in the aged rat heart.

Kerner J, Yohannes E, Lee K, Virmani A, Koverech A, Cavazza C, Chance MR, Hoppel C.

Mech Ageing Dev. 2015 Jan;145:39-50. doi: 10.1016/j.mad.2015.01.003. Epub 2015 Feb 7.


Tissue specific dysregulated protein subnetworks in type 2 diabetic bladder urothelium and detrusor muscle.

Tomechko SE, Liu G, Tao M, Schlatzer D, Powell CT, Gupta S, Chance MR, Daneshgari F.

Mol Cell Proteomics. 2015 Mar;14(3):635-45. doi: 10.1074/mcp.M114.041863. Epub 2015 Jan 8.

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