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Cholesterol crystallization within hepatocyte lipid droplets and its role in murine NASH.

Ioannou GN, Subramanian S, Chait A, Haigh WG, Yeh MM, Farrell GC, Lee SP, Savard C.

J Lipid Res. 2017 Apr 12. pii: jlr.M072454. doi: 10.1194/jlr.M072454. [Epub ahead of print]


The Single-parameter, Structure-based IsoPSA Assay Demonstrates Improved Diagnostic Accuracy for Detection of Any Prostate Cancer and High-grade Prostate Cancer Compared to a Concentration-based Assay of Total Prostate-specific Antigen: A Preliminary Report.

Klein EA, Chait A, Hafron JM, Kernen KM, Manickam K, Stephenson AJ, Wagner M, Zhu H, Kestranek A, Zaslavsky B, Stovsky M.

Eur Urol. 2017 Apr 7. pii: S0302-2838(17)30236-1. doi: 10.1016/j.eururo.2017.03.025. [Epub ahead of print]


Metabolically distinct weight loss by 10,12 CLA and caloric restriction highlight the importance of subcutaneous white adipose tissue for glucose homeostasis in mice.

den Hartigh LJ, Wang S, Goodspeed L, Wietecha T, Houston B, Omer M, Ogimoto K, Subramanian S, Gowda GA, O'Brien KD, Kaiyala KJ, Morton GJ, Chait A.

PLoS One. 2017 Feb 28;12(2):e0172912. doi: 10.1371/journal.pone.0172912. eCollection 2017.


Cutting Edge: BAFF Overexpression Reduces Atherosclerosis via TACI-Dependent B Cell Activation.

Jackson SW, Scharping NE, Jacobs HM, Wang S, Chait A, Rawlings DJ.

J Immunol. 2016 Dec 15;197(12):4529-4534. Epub 2016 Nov 11.


Analytical applications of partitioning in aqueous two-phase systems: Exploring protein structural changes and protein-partner interactions in vitro and in vivo by solvent interaction analysis method.

Zaslavsky BY, Uversky VN, Chait A.

Biochim Biophys Acta. 2016 May;1864(5):622-44. doi: 10.1016/j.bbapap.2016.02.017. Epub 2016 Feb 23. Review.


Lipids, Lipoproteins, and Cardiovascular Disease: Clinical Pharmacology Now and in the Future.

Chait A, Eckel RH.

J Clin Endocrinol Metab. 2016 Mar;101(3):804-14. doi: 10.1210/jc.2015-3940. Epub 2016 Feb 23. Review.


Serum amyloid A impairs the antiinflammatory properties of HDL.

Han CY, Tang C, Guevara ME, Wei H, Wietecha T, Shao B, Subramanian S, Omer M, Wang S, O'Brien KD, Marcovina SM, Wight TN, Vaisar T, de Beer MC, de Beer FC, Osborne WR, Elkon KB, Chait A.

J Clin Invest. 2016 Feb;126(2):796. doi: 10.1172/JCI86401. Epub 2016 Feb 1. No abstract available.


Paraphenylene diamine exacerbates platelet aggregation and thrombus formation in response to a low dose of collagen.

Zaid Y, Marhoume F, Senhaji N, Kojok K, Boufous H, Naya A, Oudghiri M, Darif Y, Habti N, Zouine S, Mohamed F, Chait A, Bagri A.

J Toxicol Sci. 2016 Feb;41(1):123-8. doi: 10.2131/jts.41.123.


Serum amyloid A impairs the antiinflammatory properties of HDL.

Han CY, Tang C, Guevara ME, Wei H, Wietecha T, Shao B, Subramanian S, Omer M, Wang S, O'Brien KD, Marcovina SM, Wight TN, Vaisar T, de Beer MC, de Beer FC, Osborne WR, Elkon KB, Chait A.

J Clin Invest. 2016 Jan;126(1):266-81. doi: 10.1172/JCI83475. Epub 2015 Dec 7. Erratum in: J Clin Invest. 2016 Feb;126(2):796.


Genetic Disorders of Triglyceride Metabolism.

Chait A, Subramanian S, Brunzell JD.

In: De Groot LJ, Chrousos G, Dungan K, Feingold KR, Grossman A, Hershman JM, Koch C, Korbonits M, McLachlan R, New M, Purnell J, Rebar R, Singer F, Vinik A, editors. Endotext [Internet]. South Dartmouth (MA):, Inc.; 2000-.
2015 Jun 12.


Solvent interaction analysis as a proteomic approach to structure-based biomarker discovery and clinical diagnostics.

Zaslavsky BY, Uversky VN, Chait A.

Expert Rev Proteomics. 2016;13(1):9-17. doi: 10.1586/14789450.2016.1116945. Epub 2015 Nov 26.


Behavioral, histopathological and biochemical impairments observed in mice envenomed by the scorpion: Hottentota gentili (Pallary, 1924).

El Hidan MA, Touloun O, El Hiba O, Chait A, Eddine Hafid J, Boumezzough A.

Toxicon. 2015 Sep;103:19-29. doi: 10.1016/j.toxicon.2015.06.013. Epub 2015 Jun 16.


Anti-HMGB1 antibody reduces weight gain in mice fed a high-fat diet.

Montes VN, Subramanian S, Goodspeed L, Wang SA, Omer M, Bobik A, Teshigawara K, Nishibori M, Chait A.

Nutr Diabetes. 2015 Jun 15;5:e161. doi: 10.1038/nutd.2015.11.


Hospital revisit rate after a diagnosis of conversion disorder.

Merkler AE, Parikh NS, Chaudhry S, Chait A, Allen NC, Navi BB, Kamel H.

J Neurol Neurosurg Psychiatry. 2016 Apr;87(4):363-6. doi: 10.1136/jnnp-2014-310181. Epub 2015 Apr 8.


The apolipoprotein-AI mimetic peptide L4F at a modest dose does not attenuate weight gain, inflammation, or atherosclerosis in LDLR-null mice.

Averill MM, Kim EJ, Goodspeed L, Wang S, Subramanian S, Den Hartigh LJ, Tang C, Ding Y, Reardon CA, Getz GS, Chait A.

PLoS One. 2014 Oct 6;9(10):e109252. doi: 10.1371/journal.pone.0109252. eCollection 2014.


Deletion of serum amyloid A3 improves high fat high sucrose diet-induced adipose tissue inflammation and hyperlipidemia in female mice.

den Hartigh LJ, Wang S, Goodspeed L, Ding Y, Averill M, Subramanian S, Wietecha T, O'Brien KD, Chait A.

PLoS One. 2014 Sep 24;9(9):e108564. doi: 10.1371/journal.pone.0108564. eCollection 2014.


Modulation of adipose tissue lipolysis and body weight by high-density lipoproteins in mice.

Wei H, Averill MM, McMillen TS, Dastvan F, Mitra P, Subramanian S, Tang C, Chait A, Leboeuf RC.

Nutr Diabetes. 2014 Feb 24;4:e108. doi: 10.1038/nutd.2014.4.


10E,12Z-conjugated linoleic acid impairs adipocyte triglyceride storage by enhancing fatty acid oxidation, lipolysis, and mitochondrial reactive oxygen species.

den Hartigh LJ, Han CY, Wang S, Omer M, Chait A.

J Lipid Res. 2013 Nov;54(11):2964-78. doi: 10.1194/jlr.M035188. Epub 2013 Aug 17.


Increased levels of invariant natural killer T lymphocytes worsen metabolic abnormalities and atherosclerosis in obese mice.

Subramanian S, Turner MS, Ding Y, Goodspeed L, Wang S, Buckner JH, O'Brien K, Getz GS, Reardon CA, Chait A.

J Lipid Res. 2013 Oct;54(10):2831-41. doi: 10.1194/jlr.M041020. Epub 2013 Aug 6.


T cell activation inhibitors reduce CD8+ T cell and pro-inflammatory macrophage accumulation in adipose tissue of obese mice.

Montes VN, Turner MS, Subramanian S, Ding Y, Hayden-Ledbetter M, Slater S, Goodspeed L, Wang S, Omer M, Den Hartigh LJ, Averill MM, O'Brien KD, Ledbetter J, Chait A.

PLoS One. 2013 Jul 2;8(7):e67709. doi: 10.1371/journal.pone.0067709. Print 2013.

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