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Items: 1 to 20 of 29

1.

Elevation in the serum and urine concentration of injury-related molecules after the formation of deep tissue injury in a rat spinal cord injury pressure ulcer model.

Makhsous M, Lin F, Pandya A, Pandya MS, Chadwick CC.

PM R. 2010 Nov;2(11):1063-5. doi: 10.1016/j.pmrj.2010.08.002. No abstract available.

2.

Estrogen receptor dependent inhibitors of NF-kappaB transcriptional activation-1 synthesis and biological evaluation of substituted 2-cyanopropanoic acid derivatives: pathway selective inhibitors of NF-kappaB, a potential treatment for rheumatoid arthritis.

Caggiano TJ, Brazzale A, Ho DM, Kraml CM, Trybulski E, Chadwick CC, Chippari S, Borges-Marcucci L, Eckert A, Keith JC, Kenney T, Harnish DC.

J Med Chem. 2007 Nov 1;50(22):5245-8. Epub 2007 Sep 29.

PMID:
17902637
3.

Control of chronic inflammation with pathway selective estrogen receptor ligands.

Steffan RJ, Matelan E, Ashwell MA, Moore WJ, Solvibile WR, Trybulski E, Chadwick CC, Chippari S, Kenney T, Winneker RC, Eckert A, Borges-Marcucci L, Adelman SJ, Xu Z, Mosyak L, Harnish DC.

Curr Top Med Chem. 2006;6(2):103-11. Review.

PMID:
16454762
4.

Synthesis and activity of a new class of pathway-selective estrogen receptor ligands: hydroxybenzoyl-3,4-dihydroquinoxalin-2(1H)-ones.

Mahaney PE, Webb MB, Ye F, Sabatucci JP, Steffan RJ, Chadwick CC, Harnish DC, Trybulski EJ.

Bioorg Med Chem. 2006 May 15;14(10):3455-66. Epub 2006 Jan 19.

PMID:
16427291
5.

The activity of pathway-selective estrogen receptor ligands in experimental septic shock.

Opal SM, Palardy JE, Cristofaro P, Parejo N, Jhung JW, Keith JC Jr, Chippari S, Caggiano TJ, Steffan RJ, Chadwick CC, Harnish DC.

Shock. 2005 Dec;24(6):535-40.

PMID:
16317384
6.

Substituted 4-hydroxyphenyl sulfonamides as pathway-selective estrogen receptor ligands.

Sabatucci JP, Ashwell MA, Trybulski E, O'Donnell MM, Moore WJ, Harnish DC, Chadwick CC.

Bioorg Med Chem Lett. 2006 Feb 15;16(4):854-8. Epub 2005 Nov 21.

PMID:
16300947
7.

The utility of pathway selective estrogen receptor ligands that inhibit nuclear factor-kappa B transcriptional activity in models of rheumatoid arthritis.

Keith JC Jr, Albert LM, Leathurby Y, Follettie M, Wang L, Borges-Marcucci L, Chadwick CC, Steffan RJ, Harnish DC.

Arthritis Res Ther. 2005;7(3):R427-38. Epub 2005 Feb 21.

8.

Identification of pathway-selective estrogen receptor ligands that inhibit NF-kappaB transcriptional activity.

Chadwick CC, Chippari S, Matelan E, Borges-Marcucci L, Eckert AM, Keith JC Jr, Albert LM, Leathurby Y, Harris HA, Bhat RA, Ashwell M, Trybulski E, Winneker RC, Adelman SJ, Steffan RJ, Harnish DC.

Proc Natl Acad Sci U S A. 2005 Feb 15;102(7):2543-8. Epub 2005 Feb 7.

9.

Synthesis and activity of substituted 4-(indazol-3-yl)phenols as pathway-selective estrogen receptor ligands useful in the treatment of rheumatoid arthritis.

Steffan RJ, Matelan E, Ashwell MA, Moore WJ, Solvibile WR, Trybulski E, Chadwick CC, Chippari S, Kenney T, Eckert A, Borges-Marcucci L, Keith JC, Xu Z, Mosyak L, Harnish DC.

J Med Chem. 2004 Dec 16;47(26):6435-8.

PMID:
15588074
10.

Estrogen receptor alpha inhibits IL-1beta induction of gene expression in the mouse liver.

Evans MJ, Lai K, Shaw LJ, Harnish DC, Chadwick CC.

Endocrinology. 2002 Jul;143(7):2559-70.

PMID:
12072388
11.

In vitro modulation of primate coronary vascular muscle cell reactivity by ovarian steroid hormones.

Minshall RD, Miyagawa K, Chadwick CC, Novy MJ, Hermsmeyer K.

FASEB J. 1998 Oct;12(13):1419-29.

PMID:
9761786
12.
13.

Antimycins, inhibitors of ATP-citrate lyase, from a Streptomyces sp.

Barrow CJ, Oleynek JJ, Marinelli V, Sun HH, Kaplita P, Sedlock DM, Gillum AM, Chadwick CC, Cooper R.

J Antibiot (Tokyo). 1997 Sep;50(9):729-33.

14.

Variant cDNA sequences of human ATP:citrate lyase: cloning, expression, and purification from baculovirus-infected insect cells.

Lord KA, Wang XM, Simmons SJ, Bruckner RC, Loscig J, O'Connor B, Bentley R, Smallwood A, Chadwick CC, Stevis PE, Ciccarelli RB.

Protein Expr Purif. 1997 Feb;9(1):133-41.

PMID:
9116495
15.

4,5-Dihydro-3-(methanesulfonamidophenyl)-1-phenyl-1H-2,4-benzodiazepines: a novel class III antiarrhythmic agents.

Johnson RE, Silver PJ, Becker R, Birsner NC, Bohnet EA, Briggs GM, Busacca CA, Canniff P, Carabateas PM, Chadwick CC, et al.

J Med Chem. 1995 Jul 7;38(14):2551-6.

PMID:
7629795
16.

Novel inhibitors of potassium ion channels on human T lymphocytes.

Michne WF, Guiles JW, Treasurywala AM, Castonguay LA, Weigelt CA, Oconnor B, Volberg WA, Grant AM, Chadwick CC, Krafte DS, et al.

J Med Chem. 1995 May 26;38(11):1877-83.

PMID:
7540207
17.

4,5-Dihydro-1-phenyl-1H-2,4-benzodiazepines: novel antiarrhythmic agents.

Johnson RE, Baizman ER, Becker C, Bohnet EA, Bell RH, Birsner NC, Busacca CA, Carabateas PM, Chadwick CC, Gruett MD, et al.

J Med Chem. 1993 Oct 29;36(22):3361-70.

PMID:
8230126
18.

Identification of a specific radioligand for the cardiac rapidly activating delayed rectifier K+ channel.

Chadwick CC, Ezrin AM, O'Connor B, Volberg WA, Smith DI, Wedge KJ, Hill RJ, Briggs GM, Pagani ED, Silver PJ, et al.

Circ Res. 1993 Mar;72(3):707-14.

19.

Inositol polyphosphate receptor and clathrin assembly protein AP-2 are related proteins that form potassium-selective ion channels in planar lipid bilayers.

Timerman AP, Mayrleitner MM, Lukas TJ, Chadwick CC, Saito A, Watterson DM, Schindler H, Fleischer S.

Proc Natl Acad Sci U S A. 1992 Oct 1;89(19):8976-80.

20.

Structural and functional characterization of an inositol polyphosphate receptor from cerebellum.

Chadwick CC, Timerman AP, Saito A, Mayrleitner M, Schindler H, Fleischer S.

J Biol Chem. 1992 Feb 15;267(5):3473-81.

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