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Items: 1 to 20 of 301

1.

Activity Based Profiling of Deubiquitylating Enzymes and Inhibitors in Animal Tissues.

McLellan L, Forder C, Cranston A, Harrigan J, Jacq X.

Methods Mol Biol. 2016;1449:411-9. doi: 10.1007/978-1-4939-3756-1_27.

PMID:
27613053
2.

Monitoring Target Engagement of Deubiquitylating Enzymes Using Activity Probes: Past, Present, and Future.

Harrigan J, Jacq X.

Methods Mol Biol. 2016;1449:395-410. doi: 10.1007/978-1-4939-3756-1_26.

PMID:
27613052
3.

ADCT-301, a Pyrrolobenzodiazepine (PBD) Dimer-Containing Antibody Drug Conjugate (ADC) Targeting CD25-Expressing Hematological Malignancies.

Flynn M, Zammarchi F, Tyrer PC, Akarca AU, Janghra N, Britten CE, Havenith CE, Levy JN, Tiberghien A, Masterson LA, Barry C, d'Hooge F, Marafioti T, Parren PW, Williams DG, Howard PW, van Berkel PH, Hartley JA.

Mol Cancer Ther. 2016 Aug 17. pii: molcanther.0233.2016. [Epub ahead of print]

PMID:
27535974
4.

Review: Comprehensive review on treatment of HIV.

Daniyal M, Akram M, Hamid A, Nawaz A, Usmanghani K, Ahmed S, Hameed L.

Pak J Pharm Sci. 2016 Jul;29(4):1331-8. Review.

PMID:
27393456
5.

Inhibition of Histone Deacetylase 6 Reveals a Potent Immunosuppressant Effect in Models of Transplantation.

Ellis JD, Neil DA, Inston NG, Jenkinson E, Drayson MT, Hampson P, Shuttleworth SJ, Ready AR, Cobbold M.

Transplantation. 2016 Aug;100(8):1667-74. doi: 10.1097/TP.0000000000001208.

PMID:
27222932
6.

Ways to manage hepatitis C without cirrhosis: Treatment by comparison of coded eastern medicine hepcinal with interferon alpha 2b and ribavirin.

Nawaz A, Nazar H, Usmanghani K, Sheikh ZA, Chishti MA, Ahmad I.

Pak J Pharm Sci. 2016 May;29(3):919-27.

PMID:
27166535
7.

Characterization of age-dependent changes in the striatum: Response to the mitochondrial toxin 3-nitropropionic acid.

Shinomol GK, Ranganayaki S, Joshi AK, Gayathri N, Gowda H, Muralidhara, Srinivas Bharath MM.

Mech Ageing Dev. 2016 Apr 30. pii: S0047-6374(16)30050-1. doi: 10.1016/j.mad.2016.04.008. [Epub ahead of print]

PMID:
27143313
8.

Physiological modulators of Kv3.1 channels adjust firing patterns of auditory brain stem neurons.

Brown MR, El-Hassar L, Zhang Y, Alvaro G, Large CH, Kaczmarek LK.

J Neurophysiol. 2016 Jul 1;116(1):106-21. doi: 10.1152/jn.00174.2016. Epub 2016 Apr 6.

PMID:
27052580
9.

Kv3.3 Channels Bind Hax-1 and Arp2/3 to Assemble a Stable Local Actin Network that Regulates Channel Gating.

Zhang Y, Zhang XF, Fleming MR, Amiri A, El-Hassar L, Surguchev AA, Hyland C, Jenkins DP, Desai R, Brown MR, Gazula VR, Waters MF, Large CH, Horvath TL, Navaratnam D, Vaccarino FM, Forscher P, Kaczmarek LK.

Cell. 2016 Apr 7;165(2):434-48. doi: 10.1016/j.cell.2016.02.009. Epub 2016 Mar 17.

PMID:
26997484
10.

A New Series of Orally Bioavailable Chemokine Receptor 9 (CCR9) Antagonists; Possible Agents for the Treatment of Inflammatory Bowel Disease.

Kalindjian SB, Kadnur SV, Hewson CA, Venkateshappa C, Juluri S, Kristam R, Kulkarni B, Mohammed Z, Saxena R, Viswanadhan VN, Aiyar J, McVey D.

J Med Chem. 2016 Apr 14;59(7):3098-111. doi: 10.1021/acs.jmedchem.5b01840. Epub 2016 Mar 17.

PMID:
26987013
11.

Hypothalamic leptin action is mediated by histone deacetylase 5.

Kabra DG, Pfuhlmann K, García-Cáceres C, Schriever SC, Casquero García V, Kebede AF, Fuente-Martin E, Trivedi C, Heppner K, Uhlenhaut NH, Legutko B, Kabra UD, Gao Y, Yi CX, Quarta C, Clemmensen C, Finan B, Müller TD, Meyer CW, Paez-Pereda M, Stemmer K, Woods SC, Perez-Tilve D, Schneider R, Olson EN, Tschöp MH, Pfluger PT.

Nat Commun. 2016 Feb 29;7:10782. doi: 10.1038/ncomms10782.

12.

Diagnostic and Therapeutic Implications of Histone Epigenetic Modulators in Breast Cancer.

Walsh L, Gallagher WM, O'Connor DP, Ní Chonghaile T.

Expert Rev Mol Diagn. 2016;16(5):541-51. doi: 10.1586/14737159.2016.1156534. Epub 2016 Mar 16.

PMID:
26895288
13.

MPX-004 and MPX-007: New Pharmacological Tools to Study the Physiology of NMDA Receptors Containing the GluN2A Subunit.

Volkmann RA, Fanger CM, Anderson DR, Sirivolu VR, Paschetto K, Gordon E, Virginio C, Gleyzes M, Buisson B, Steidl E, Mierau SB, Fagiolini M, Menniti FS.

PLoS One. 2016 Feb 1;11(2):e0148129. doi: 10.1371/journal.pone.0148129. eCollection 2016. Erratum in: PLoS One. 2016;11(3):e0151452.

14.

Impact of resistance exercise on ribosome biogenesis is acutely regulated by post-exercise recovery strategies.

Figueiredo VC, Roberts LA, Markworth JF, Barnett MP, Coombes JS, Raastad T, Peake JM, Cameron-Smith D.

Physiol Rep. 2016 Feb;4(2). pii: e12670. doi: 10.14814/phy2.12670.

15.

A novel multi-CDK inhibitor P1446A-05 restricts melanoma growth and produces synergistic effects in combination with MAPK pathway inhibitors.

Eliades P, Miller DM, Miao B, Kumar R, Taylor M, Buch S, Srinivasa SP, Flaherty KT, Tsao H.

Cancer Biol Ther. 2016 Jul 2;17(7):778-84. doi: 10.1080/15384047.2016.1139267.

PMID:
26810603
16.

Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy.

Raman MC, Rizkallah PJ, Simmons R, Donnellan Z, Dukes J, Bossi G, Le Provost GS, Todorov P, Baston E, Hickman E, Mahon T, Hassan N, Vuidepot A, Sami M, Cole DK, Jakobsen BK.

Sci Rep. 2016 Jan 13;6:18851. doi: 10.1038/srep18851.

17.

Mesenchymoangioblast-derived mesenchymal stromal cells inhibit cell damage, tissue damage and improve peripheral blood flow following hindlimb ischemic injury in mice.

Koch JM, D'Souza SS, Schwahn DJ, Dixon I, Hacker TA.

Cytotherapy. 2016 Feb;18(2):219-28. doi: 10.1016/j.jcyt.2015.10.013. Epub 2015 Dec 28.

PMID:
26740280
18.

In Vivo Assessment of Bone Regeneration in Alginate/Bone ECM Hydrogels with Incorporated Skeletal Stem Cells and Single Growth Factors.

Gothard D, Smith EL, Kanczler JM, Black CR, Wells JA, Roberts CA, White LJ, Qutachi O, Peto H, Rashidi H, Rojo L, Stevens MM, El Haj AJ, Rose FR, Shakesheff KM, Oreffo RO.

PLoS One. 2015 Dec 16;10(12):e0145080. doi: 10.1371/journal.pone.0145080. eCollection 2015.

19.
20.

Generation of Efficient Germ-Line Chimeras Using Embryonic Stem Cell Injection.

Ritchie WA.

Methods Mol Biol. 2015;1330:113-23. doi: 10.1007/978-1-4939-2848-4_11.

PMID:
26621594
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