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Items: 12


LaminA/C regulates epigenetic and chromatin architecture changes upon aging of hematopoietic stem cells.

Grigoryan A, Guidi N, Senger K, Liehr T, Soller K, Marka G, Vollmer A, Markaki Y, Leonhardt H, Buske C, Lipka DB, Plass C, Zheng Y, Mulaw MA, Geiger H, Florian MC.

Genome Biol. 2018 Nov 7;19(1):189. doi: 10.1186/s13059-018-1557-3.


Aging alters the epigenetic asymmetry of HSC division.

Florian MC, Klose M, Sacma M, Jablanovic J, Knudson L, Nattamai KJ, Marka G, Vollmer A, Soller K, Sakk V, Cabezas-Wallscheid N, Zheng Y, Mulaw MA, Glauche I, Geiger H.

PLoS Biol. 2018 Sep 20;16(9):e2003389. doi: 10.1371/journal.pbio.2003389. eCollection 2018 Sep.


Aged murine hematopoietic stem cells drive aging-associated immune remodeling.

Leins H, Mulaw M, Eiwen K, Sakk V, Liang Y, Denkinger M, Geiger H, Schirmbeck R.

Blood. 2018 Aug 9;132(6):565-576. doi: 10.1182/blood-2018-02-831065. Epub 2018 Jun 11.


Expression and Activity of the Small RhoGTPase Cdc42 in Blood Cells of Older Adults Are Associated With Age and Cardiovascular Disease.

Florian MC, Klenk J, Marka G, Soller K, Kiryakos H, Peter R, Herbolsheimer F, Rothenbacher D, Denkinger M, Geiger H.

J Gerontol A Biol Sci Med Sci. 2017 Sep 1;72(9):1196-1200. doi: 10.1093/gerona/glx091.


Regulation of hematopoietic stem cell aging by the small RhoGTPase Cdc42.

Geiger H, Zheng Y.

Exp Cell Res. 2014 Dec 10;329(2):214-9. doi: 10.1016/j.yexcr.2014.09.001. Epub 2014 Sep 16. Review.


Cdc42 and aging of hematopoietic stem cells.

Geiger H, Zheng Y.

Curr Opin Hematol. 2013 Jul;20(4):295-300. doi: 10.1097/MOH.0b013e3283615aba. Review.


Alcam regulates long-term hematopoietic stem cell engraftment and self-renewal.

Jeannet R, Cai Q, Liu H, Vu H, Kuo YH.

Stem Cells. 2013 Mar;31(3):560-71. doi: 10.1002/stem.1309.


Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation.

Florian MC, Dörr K, Niebel A, Daria D, Schrezenmeier H, Rojewski M, Filippi MD, Hasenberg A, Gunzer M, Scharffetter-Kochanek K, Zheng Y, Geiger H.

Cell Stem Cell. 2012 May 4;10(5):520-30. doi: 10.1016/j.stem.2012.04.007.


Concise review: polarity in stem cells, disease, and aging.

Florian MC, Geiger H.

Stem Cells. 2010 Sep;28(9):1623-9. doi: 10.1002/stem.481. Review.


Stem cells, aging, niche, adhesion and Cdc42: a model for changes in cell-cell interactions and hematopoietic stem cell aging.

Geiger H, Koehler A, Gunzer M.

Cell Cycle. 2007 Apr 15;6(8):884-7. Epub 2007 Apr 7.


Increased hematopoietic stem cell mobilization in aged mice.

Xing Z, Ryan MA, Daria D, Nattamai KJ, Van Zant G, Wang L, Zheng Y, Geiger H.

Blood. 2006 Oct 1;108(7):2190-7. Epub 2006 Jun 1.

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