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Items: 16


An Autotaxin-LPA-IL-6 Amplification Loop Drives Scleroderma Fibrosis.

Castelino FV, Bain G, Pace VA, Black KE, George L, Probst CK, Goulet L, Lafyatis R, Tager AM.

Arthritis Rheumatol. 2016 Jul 7. doi: 10.1002/art.39797.


Autotaxin activity increases locally following lung injury, but is not required for pulmonary lysophosphatidic acid production or fibrosis.

Black KE, Berdyshev E, Bain G, Castelino FV, Shea BS, Probst CK, Fontaine BA, Bronova I, Goulet L, Lagares D, Ahluwalia N, Knipe RS, Natarajan V, Tager AM.

FASEB J. 2016 Jun;30(6):2435-50. doi: 10.1096/fj.201500197R.


Clonal expansion of CD4(+) cytotoxic T lymphocytes in patients with IgG4-related disease.

Mattoo H, Mahajan VS, Maehara T, Deshpande V, Della-Torre E, Wallace ZS, Kulikova M, Drijvers JM, Daccache J, Carruthers MN, Castelino FV, Stone JR, Stone JH, Pillai S.

J Allergy Clin Immunol. 2016 Sep;138(3):825-38. doi: 10.1016/j.jaci.2015.12.1330.


Patient Perspectives in OMERACT Provide an Anchor for Future Metric Development and Improved Approaches to Healthcare Delivery in Connective Tissue Disease Related Interstitial Lung Disease (CTD-ILD).

Mittoo S, Frankel S, LeSage D, Strand V, Shah AA, Christopher-Stine L, Danoff S, Hummers LK, Swigris JJ, Huscher D, Christensen AM, Cenac SL, Erbil JK, Ferguson S, Garcia-Valladares I, Grewal HK, Orbai AM, Smith KC, Tran M, Bingham CO 3rd, Castelino FV, Fischer A, Saketkoo LA.

Curr Respir Med Rev. 2015 Jun;11(2):175-183.


Interstitial lung disease in scleroderma.

Schoenfeld SR, Castelino FV.

Rheum Dis Clin North Am. 2015 May;41(2):237-48. doi: 10.1016/j.rdc.2014.12.005. Review.


Barriers to and Facilitators of a Career as a Physician-Scientist Among Rheumatologists in the US.

Ogdie A, Shah AA, Makris UE, Jiang Y, Nelson AE, Kim AH, Angeles-Han ST, Castelino FV, Golding A, Muscal E, Kahlenberg JM, Barg FK; American College of Rheumatology Early Career Investigator Subcommittee of the Committee on Research..

Arthritis Care Res (Hoboken). 2015 Sep;67(9):1191-201. doi: 10.1002/acr.22569.


A 30-Year-Old Woman With Chest Pain and Coronary Artery Aneurysms.

Honigberg MC, Wallace ZS, Castelino FV.

Arthritis Care Res (Hoboken). 2016 Sep;68(9):1378-84. doi: 10.1002/acr.22476. No abstract available.


Emerging cellular and molecular targets in fibrosis: implications for scleroderma pathogenesis and targeted therapy.

Castelino FV, Varga J.

Curr Opin Rheumatol. 2014 Nov;26(6):607-14. doi: 10.1097/BOR.0000000000000110. Review.


Connective tissue disease related interstitial lung diseases and idiopathic pulmonary fibrosis: provisional core sets of domains and instruments for use in clinical trials.

Saketkoo LA, Mittoo S, Huscher D, Khanna D, Dellaripa PF, Distler O, Flaherty KR, Frankel S, Oddis CV, Denton CP, Fischer A, Kowal-Bielecka OM, LeSage D, Merkel PA, Phillips K, Pittrow D, Swigris J, Antoniou K, Baughman RP, Castelino FV, Christmann RB, Christopher-Stine L, Collard HR, Cottin V, Danoff S, Highland KB, Hummers L, Shah AA, Kim DS, Lynch DA, Miller FW, Proudman SM, Richeldi L, Ryu JH, Sandorfi N, Sarver C, Wells AU, Strand V, Matteson EL, Brown KK, Seibold JR; CTD-ILD Special Interest Group..

Thorax. 2014 May;69(5):428-36. doi: 10.1136/thoraxjnl-2013-204202. Erratum in: Thorax. 2014 Sep;69(9):834. CTD-ILD Special Interest Group [added]; multiple investigator names added.


Current status of systemic sclerosis biomarkers: applications for diagnosis, management and drug development.

Castelino FV, Varga J.

Expert Rev Clin Immunol. 2013 Nov;9(11):1077-90. doi: 10.1586/1744666X.2013.848792. Review.


Lipids and eicosanoids in fibrosis: emerging targets for therapy.

Castelino FV.

Curr Opin Rheumatol. 2012 Nov;24(6):649-55. Review.


Amelioration of dermal fibrosis by genetic deletion or pharmacologic antagonism of lysophosphatidic acid receptor 1 in a mouse model of scleroderma.

Castelino FV, Seiders J, Bain G, Brooks SF, King CD, Swaney JS, Lorrain DS, Chun J, Luster AD, Tager AM.

Arthritis Rheum. 2011 May;63(5):1405-15. doi: 10.1002/art.30262.


Interstitial lung disease in connective tissue diseases: evolving concepts of pathogenesis and management.

Castelino FV, Varga J.

Arthritis Res Ther. 2010;12(4):213. doi: 10.1186/ar3097. Review.


The impact of rheumatological evaluation in the management of patients with interstitial lung disease.

Castelino FV, Goldberg H, Dellaripa PF.

Rheumatology (Oxford). 2011 Mar;50(3):489-93. doi: 10.1093/rheumatology/keq233.


Tyrosine kinase inhibitors in systemic sclerosis: the case for imatinib.

Castelino FV, Bhattacharyya S, Varga J.

Curr Rheumatol Rep. 2009 Jul;11(3):161-3. No abstract available.


A 36-year-old man with paresthesias and a headache.

Castelino FV, Wasfy JH, Collier D.

Arthritis Rheum. 2008 Sep 15;59(9):1358-65. doi: 10.1002/art.24008. No abstract available.

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