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Items: 1 to 20 of 105

1.

Microfluidic-enhanced 3D bioprinting of aligned myoblast-laden hydrogels leads to functionally organized myofibers in vitro and in vivo.

Costantini M, Testa S, Mozetic P, Barbetta A, Fuoco C, Fornetti E, Tamiro F, Bernardini S, Jaroszewicz J, Święszkowski W, Trombetta M, Castagnoli L, Seliktar D, Garstecki P, Cesareni G, Cannata S, Rainer A, Gargioli C.

Biomaterials. 2017 Jul;131:98-110. doi: 10.1016/j.biomaterials.2017.03.026. Epub 2017 Mar 23.

2.

Both Intrinsic Substrate Preference and Network Context Contribute to Substrate Selection of Classical Tyrosine Phosphatases.

Palma A, Tinti M, Paoluzi S, Santonico E, Brandt BW, Hooft van Huijsduijnen R, Masch A, Heringa J, Schutkowski M, Castagnoli L, Cesareni G.

J Biol Chem. 2017 Mar 24;292(12):4942-4952. doi: 10.1074/jbc.M116.757518. Epub 2017 Feb 3.

PMID:
28159843
3.

The cell-autonomous mechanisms underlying the activity of metformin as an anticancer drug.

Sacco F, Calderone A, Castagnoli L, Cesareni G.

Br J Cancer. 2016 Dec 6;115(12):1451-1456. doi: 10.1038/bjc.2016.385. Epub 2016 Nov 22. Review.

4.

Pathobiological implications of the d16HER2 splice variant for stemness and aggressiveness of HER2-positive breast cancer.

Castagnoli L, Ghedini GC, Koschorke A, Triulzi T, Dugo M, Gasparini P, Casalini P, Palladini A, Iezzi M, Lamolinara A, Lollini PL, Nanni P, Chiodoni C, Tagliabue E, Pupa SM.

Oncogene. 2017 Mar 23;36(12):1721-1732. doi: 10.1038/onc.2016.338. Epub 2016 Sep 19.

5.

A subset of RAB proteins modulates PP2A phosphatase activity.

Sacco F, Mattioni A, Boldt K, Panni S, Santonico E, Castagnoli L, Ueffing M, Cesareni G.

Sci Rep. 2016 Sep 9;6:32857. doi: 10.1038/srep32857.

6.

Deep Proteomics of Breast Cancer Cells Reveals that Metformin Rewires Signaling Networks Away from a Pro-growth State.

Sacco F, Silvestri A, Posca D, Pirrò S, Gherardini PF, Castagnoli L, Mann M, Cesareni G.

Cell Syst. 2016 Mar 23;2(3):159-71. doi: 10.1016/j.cels.2016.02.005. Epub 2016 Mar 3.

7.

Characterization by mass cytometry of different methods for the preparation of muscle mononuclear cells.

Spada F, Fuoco C, Pirrò S, Paoluzi S, Castagnoli L, Gargioli C, Cesareni G.

N Biotechnol. 2016 Sep 25;33(5 Pt A):514-23. doi: 10.1016/j.nbt.2015.12.007. Epub 2016 Jan 7.

8.

SIGNOR: a database of causal relationships between biological entities.

Perfetto L, Briganti L, Calderone A, Cerquone Perpetuini A, Iannuccelli M, Langone F, Licata L, Marinkovic M, Mattioni A, Pavlidou T, Peluso D, Petrilli LL, Pirrò S, Posca D, Santonico E, Silvestri A, Spada F, Castagnoli L, Cesareni G.

Nucleic Acids Res. 2016 Jan 4;44(D1):D548-54. doi: 10.1093/nar/gkv1048. Epub 2015 Oct 13.

9.

Alterations in the phosphoproteomic profile of cells expressing a non-functional form of the SHP2 phosphatase.

Corallino S, Iwai LK, Payne LS, Huang PH, Sacco F, Cesareni G, Castagnoli L.

N Biotechnol. 2016 Sep 25;33(5 Pt A):524-36. doi: 10.1016/j.nbt.2015.08.002. Epub 2015 Aug 24.

PMID:
26316256
10.

Metformin Induces Apoptosis and Downregulates Pyruvate Kinase M2 in Breast Cancer Cells Only When Grown in Nutrient-Poor Conditions.

Silvestri A, Palumbo F, Rasi I, Posca D, Pavlidou T, Paoluzi S, Castagnoli L, Cesareni G.

PLoS One. 2015 Aug 20;10(8):e0136250. doi: 10.1371/journal.pone.0136250. eCollection 2015.

11.

HSPH1 inhibition downregulates Bcl-6 and c-Myc and hampers the growth of human aggressive B-cell non-Hodgkin lymphoma.

Zappasodi R, Ruggiero G, Guarnotta C, Tortoreto M, Tringali C, Cavanè A, Cabras AD, Castagnoli L, Venerando B, Zaffaroni N, Gianni AM, De Braud F, Tripodo C, Pupa SM, Di Nicola M.

Blood. 2015 Mar 12;125(11):1768-71. doi: 10.1182/blood-2014-07-590034. Epub 2015 Jan 8.

12.

Metformin protects skeletal muscle from cardiotoxin induced degeneration.

Langone F, Cannata S, Fuoco C, Lettieri Barbato D, Testa S, Nardozza AP, Ciriolo MR, Castagnoli L, Gargioli C, Cesareni G.

PLoS One. 2014 Dec 2;9(12):e114018. doi: 10.1371/journal.pone.0114018. eCollection 2014.

13.

The adapter protein CD2AP binds to p53 protein in the cytoplasm and can discriminate its polymorphic variants P72R.

Panni S, Salvioli S, Santonico E, Langone F, Storino F, Altilia S, Franceschi C, Cesareni G, Castagnoli L.

J Biochem. 2015 Feb;157(2):101-11. doi: 10.1093/jb/mvu059. Epub 2014 Sep 26.

PMID:
25261582
14.

RNF11 is a GGA protein cargo and acts as a molecular adaptor for GGA3 ubiquitination mediated by Itch.

Santonico E, Mattioni A, Panni S, Belleudi F, Mattei M, Torrisi MR, Cesareni G, Castagnoli L.

Oncogene. 2015 Jun;34(26):3377-90. doi: 10.1038/onc.2014.256. Epub 2014 Sep 8.

PMID:
25195858
15.

Activated d16HER2 homodimers and SRC kinase mediate optimal efficacy for trastuzumab.

Castagnoli L, Iezzi M, Ghedini GC, Ciravolo V, Marzano G, Lamolinara A, Zappasodi R, Gasparini P, Campiglio M, Amici A, Chiodoni C, Palladini A, Lollini PL, Triulzi T, Menard S, Nanni P, Tagliabue E, Pupa SM.

Cancer Res. 2014 Nov 1;74(21):6248-59. doi: 10.1158/0008-5472.CAN-14-0983. Epub 2014 Aug 27.

16.

Combining affinity proteomics and network context to identify new phosphatase substrates and adapters in growth pathways.

Sacco F, Boldt K, Calderone A, Panni S, Paoluzi S, Castagnoli L, Ueffing M, Cesareni G.

Front Genet. 2014 May 7;5:115. doi: 10.3389/fgene.2014.00115. eCollection 2014.

17.

Low body weight in females is a risk factor for increased tenofovir exposure and drug-related adverse events.

Gervasoni C, Meraviglia P, Landonio S, Baldelli S, Fucile S, Castagnoli L, Clementi E, Riva A, Galli M, Rizzardini G, Cattaneo D.

PLoS One. 2013 Dec 2;8(12):e80242. doi: 10.1371/journal.pone.0080242. eCollection 2013.

18.

mentha: a resource for browsing integrated protein-interaction networks.

Calderone A, Castagnoli L, Cesareni G.

Nat Methods. 2013 Aug;10(8):690-1. doi: 10.1038/nmeth.2561. No abstract available.

PMID:
23900247
19.

The SH2 domain interaction landscape.

Tinti M, Kiemer L, Costa S, Miller ML, Sacco F, Olsen JV, Carducci M, Paoluzi S, Langone F, Workman CT, Blom N, Machida K, Thompson CM, Schutkowski M, Brunak S, Mann M, Mayer BJ, Castagnoli L, Cesareni G.

Cell Rep. 2013 Apr 25;3(4):1293-305. doi: 10.1016/j.celrep.2013.03.001. Epub 2013 Mar 28.

20.

Mapping the human phosphatome on growth pathways.

Sacco F, Gherardini PF, Paoluzi S, Saez-Rodriguez J, Helmer-Citterich M, Ragnini-Wilson A, Castagnoli L, Cesareni G.

Mol Syst Biol. 2012;8:603. doi: 10.1038/msb.2012.36.

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