Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1983 1
1984 1
1985 1
1988 1
1989 1
1990 2
1991 2
1992 8
1993 8
1994 15
1995 15
1996 20
1997 32
1998 29
1999 29
2000 31
2001 39
2002 33
2003 33
2004 48
2005 52
2006 57
2007 75
2008 72
2009 74
2010 74
2011 78
2012 88
2013 88
2014 79
2015 81
2016 76
2017 93
2018 85
2019 78
2020 74
2021 89
2022 76
2023 67
2024 22

Text availability

Article attribute

Article type

Publication date

Search Results

1,625 results

Results by year

Filters applied: . Clear all
Page 1
Cartilage Oligomeric Matrix Protein, Diseases, and Therapeutic Opportunities.
Cui J, Zhang J. Cui J, et al. Int J Mol Sci. 2022 Aug 17;23(16):9253. doi: 10.3390/ijms23169253. Int J Mol Sci. 2022. PMID: 36012514 Free PMC article. Review.
Cartilage oligomeric matrix protein (COMP) is an extracellular matrix (ECM) glycoprotein that is critical for collagen assembly and ECM stability. ...The roles of COMP in other skeleton diseases, such as osteoarthritis, have been implied. As a w …
Cartilage oligomeric matrix protein (COMP) is an extracellular matrix (ECM) glycoprotein that is critical …
Cartilage oligomeric matrix protein: COMPopathies and beyond.
Posey KL, Coustry F, Hecht JT. Posey KL, et al. Matrix Biol. 2018 Oct;71-72:161-173. doi: 10.1016/j.matbio.2018.02.023. Epub 2018 Mar 9. Matrix Biol. 2018. PMID: 29530484 Free PMC article. Review.
Cartilage oligomeric matrix protein (COMP) is a large pentameric glycoprotein that interacts with multiple extracellular matrix proteins in cartilage and other tissues. ...The most exciting clinical application is the use of COMP as a bio …
Cartilage oligomeric matrix protein (COMP) is a large pentameric glycoprotein that interacts with multiple extra …
Cartilage Oligomeric Matrix Protein: Matricellular and Matricrine Signaling in Cardiovascular Homeostasis and Disease.
Fu Y, Kong W. Fu Y, et al. Curr Vasc Pharmacol. 2017;15(3):186-196. doi: 10.2174/1570161115666170201121232. Curr Vasc Pharmacol. 2017. PMID: 28155614 Review.
Increasing the understanding of the pathogenesis of various CV diseases may provide novel therapeutic targets to improve their prevention and treatment. Cartilage oligomeric matrix protein (COMP), also known as thrombospondin-5 (TSP-5), is a matricellu …
Increasing the understanding of the pathogenesis of various CV diseases may provide novel therapeutic targets to improve their prevention an …
Health consequences of mutant cartilage oligomeric matrix protein and its relationship to abnormal growth and joint degeneration.
Hecht JT, Chiu F, Veerisetty A, Hossain M, Posey KL. Hecht JT, et al. Matrix Biol. 2023 May;119:101-111. doi: 10.1016/j.matbio.2023.03.008. Epub 2023 Mar 30. Matrix Biol. 2023. PMID: 37001593 Review.
Cartilage oligomeric matrix protein (COMP), an extracellular matrix protein, has been shown to enhance proliferation and mechanical integrity in the matrix, supporting functions of the growth plate and articular cartilage. . …
Cartilage oligomeric matrix protein (COMP), an extracellular matrix protein, has been shown to enh …
Cartilage oligomeric matrix protein is an endogenous beta-arrestin-2-selective allosteric modulator of AT1 receptor counteracting vascular injury.
Fu Y, Huang Y, Yang Z, Chen Y, Zheng J, Mao C, Li Z, Liu Z, Yu B, Li T, Wang M, Xu C, Zhou Y, Zhao G, Jia Y, Guo W, Jia X, Zhang T, Li L, Liu Z, Guo S, Ma M, Zhang H, Liu B, Du J, Wang W, Tang C, Gao P, Xu Q, Wang X, Liu J, Sun J, Kong W. Fu Y, et al. Cell Res. 2021 Jul;31(7):773-790. doi: 10.1038/s41422-020-00464-8. Epub 2021 Jan 28. Cell Res. 2021. PMID: 33510386 Free PMC article.
Compelling evidence has revealed that biased activation of G protein-coupled receptor (GPCR) signaling, including angiotensin II (AngII) receptor type 1 (AT1) signaling, plays pivotal roles in vascular homeostasis and injury, but whether a clinically relevant endogenous bi …
Compelling evidence has revealed that biased activation of G protein-coupled receptor (GPCR) signaling, including angiotensin II (Ang …
COMP (Cartilage Oligomeric Matrix Protein), a Novel PIEZO1 Regulator That Controls Blood Pressure.
Wang H, Yuan Z, Wang B, Li B, Lv H, He J, Huang Y, Cui Z, Ma Q, Li T, Fu Y, Tan X, Liu Y, Wang S, Wang C, Kong W, Zhu Y. Wang H, et al. Hypertension. 2022 Mar;79(3):549-561. doi: 10.1161/HYPERTENSIONAHA.121.17972. Epub 2022 Jan 5. Hypertension. 2022. PMID: 34983194
BACKGROUND: Vascular endothelial cells are critical for maintaining blood pressure (BP) by releasing biologically active molecules, such as nitric oxide. A non-endothelial cell resident matricellular protein, COMP (cartilage oligomeric matrix protei …
BACKGROUND: Vascular endothelial cells are critical for maintaining blood pressure (BP) by releasing biologically active molecules, such as …
Cartilage oligomeric matrix protein as a marker of progressive liver fibrosis in biliary atresia.
Udomsinprasert W, Angkathunyakul N, Jittikoon J, Chaikledkaew U, Vejchapipat P, Poovorawan Y, Honsawek S. Udomsinprasert W, et al. Sci Rep. 2021 Aug 17;11(1):16695. doi: 10.1038/s41598-021-95805-x. Sci Rep. 2021. PMID: 34404836 Free PMC article.
This study aimed to determine whether mRNA and protein levels of cartilage oligomeric matrix protein (COMP), a glycoprotein responsible for modulating homeostasis of extracellular matrix, in the systemic and local liver environments were …
This study aimed to determine whether mRNA and protein levels of cartilage oligomeric matrix protein (COM …
Cartilage oligomeric matrix protein (COMP) promotes cell proliferation in early-onset colon cancer tumorigenesis.
Nfonsam VN, Jecius HC, Janda J, Omesiete PN, Elquza E, Scott AJ, Nfonsam LE, Jandova J. Nfonsam VN, et al. Surg Endosc. 2020 Sep;34(9):3992-3998. doi: 10.1007/s00464-019-07185-z. Epub 2019 Oct 15. Surg Endosc. 2020. PMID: 31617091
Our recently published data showed that EOCC is a distinct disease with unique molecular features compared to late-onset CC (LOCC). The Cartilage Oligomeric Matrix Protein (COMP) was shown to be significantly upregulated in EOCC and correlated with poo …
Our recently published data showed that EOCC is a distinct disease with unique molecular features compared to late-onset CC (LOCC). The C …
The role of cartilage oligomeric matrix protein (COMP) in skeletal disease.
Posey KL, Hecht JT. Posey KL, et al. Curr Drug Targets. 2008 Oct;9(10):869-77. doi: 10.2174/138945008785909293. Curr Drug Targets. 2008. PMID: 18855621 Review.
Cartilage oligomeric matrix protein is a non-collagenous extracellular matrix protein expressed primarily in cartilage, ligament, and tendon. ...Recent studies have identified molecular functions of cartilage oligomeric …
Cartilage oligomeric matrix protein is a non-collagenous extracellular matrix protein expressed pr …
COMP (Cartilage Oligomeric Matrix Protein) Neoepitope: A Novel Biomarker to Identify Symptomatic Carotid Stenosis.
Sandstedt J, Vargmar K, Björkman K, Ruetschi U, Bergström G, Hultén LM, Skiöldebrand E. Sandstedt J, et al. Arterioscler Thromb Vasc Biol. 2021 Mar;41(3):1218-1228. doi: 10.1161/ATVBAHA.120.314720. Epub 2021 Jan 21. Arterioscler Thromb Vasc Biol. 2021. PMID: 33472398 Free PMC article.
OBJECTIVE: COMP (cartilage oligomeric matrix protein) is abundantly expressed in the cardiovascular system, cartilage, and atherosclerotic plaques. ...When the concentration was compared between the stenosis and control groups, IL-1ra (interleuk …
OBJECTIVE: COMP (cartilage oligomeric matrix protein) is abundantly expressed in the cardiovascular system, c …
1,625 results