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Items: 1 to 20 of 54


Tumor-Infiltrating Lymphocytes in the Checkpoint Inhibitor Era.

Linette GP, Carreno BM.

Curr Hematol Malig Rep. 2019 Jun 11. doi: 10.1007/s11899-019-00523-x. [Epub ahead of print] Review.


Heating up cancer vaccines.

Ghassemi S, Carreno BM.

Sci Immunol. 2017 Nov 10;2(17). pii: eaap9419. doi: 10.1126/sciimmunol.aap9419.


Neoantigen Vaccines Pass the Immunogenicity Test.

Linette GP, Carreno BM.

Trends Mol Med. 2017 Oct;23(10):869-871. doi: 10.1016/j.molmed.2017.08.007. Epub 2017 Aug 31.


Selective targeting of IL-2 to NKG2D bearing cells for improved immunotherapy.

Ghasemi R, Lazear E, Wang X, Arefanian S, Zheleznyak A, Carreno BM, Higashikubo R, Gelman AE, Kreisel D, Fremont DH, Krupnick AS.

Nat Commun. 2016 Sep 21;7:12878. doi: 10.1038/ncomms12878.


A Vaccine for Cancer?

Carreno BM, Mardis ER.

Sci Am. 2016 Apr;314(4):46. doi: 10.1038/scientificamerican0416-46. No abstract available.


pVAC-Seq: A genome-guided in silico approach to identifying tumor neoantigens.

Hundal J, Carreno BM, Petti AA, Linette GP, Griffith OL, Mardis ER, Griffith M.

Genome Med. 2016 Jan 29;8(1):11. doi: 10.1186/s13073-016-0264-5.


Cancer immunotherapy. A dendritic cell vaccine increases the breadth and diversity of melanoma neoantigen-specific T cells.

Carreno BM, Magrini V, Becker-Hapak M, Kaabinejadian S, Hundal J, Petti AA, Ly A, Lie WR, Hildebrand WH, Mardis ER, Linette GP.

Science. 2015 May 15;348(6236):803-8. doi: 10.1126/science.aaa3828. Epub 2015 Apr 2.


Dendritic cell-based vaccines: Shining the spotlight on signal 3.

Linette GP, Carreno BM.

Oncoimmunology. 2013 Nov 1;2(11):e26512. Epub 2013 Oct 10.


IL-12p70-producing patient DC vaccine elicits Tc1-polarized immunity.

Carreno BM, Becker-Hapak M, Huang A, Chan M, Alyasiry A, Lie WR, Aft RL, Cornelius LA, Trinkaus KM, Linette GP.

J Clin Invest. 2013 Aug;123(8):3383-94. doi: 10.1172/JCI68395. Epub 2013 Jul 11.


Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma.

Linette GP, Stadtmauer EA, Maus MV, Rapoport AP, Levine BL, Emery L, Litzky L, Bagg A, Carreno BM, Cimino PJ, Binder-Scholl GK, Smethurst DP, Gerry AB, Pumphrey NJ, Bennett AD, Brewer JE, Dukes J, Harper J, Tayton-Martin HK, Jakobsen BK, Hassan NJ, Kalos M, June CH.

Blood. 2013 Aug 8;122(6):863-71. doi: 10.1182/blood-2013-03-490565. Epub 2013 Jun 14.


Strain-specific variation in murine natural killer gene complex contributes to differences in immunosurveillance for urethane-induced lung cancer.

Kreisel D, Gelman AE, Higashikubo R, Lin X, Vikis HG, White JM, Toth KA, Deshpande C, Carreno BM, You M, Taffner SM, Yokoyama WM, Bui JD, Schreiber RD, Krupnick AS.

Cancer Res. 2012 Sep 1;72(17):4311-7. Epub 2012 Jun 29.


Amino-terminal extended peptide single-chain trimers are potent synthetic agonists for memory human CD8+ T cells.

Carreno BM, Becker-Hapak M, Chan M, Lie WR, Wang X, Hansen TH, Linette GP.

J Immunol. 2012 Jun 15;188(12):5839-49. doi: 10.4049/jimmunol.1103647. Epub 2012 May 9.


Cancer genome sequencing and its implications for personalized cancer vaccines.

Li L, Goedegebuure P, Mardis ER, Ellis MJ, Zhang X, Herndon JM, Fleming TP, Carreno BM, Hansen TH, Gillanders WE.

Cancers (Basel). 2011 Nov 25;3(4):4191-211. doi: 10.3390/cancers3044191.


Immunodeficient mouse strains display marked variability in growth of human melanoma lung metastases.

Carreno BM, Garbow JR, Kolar GR, Jackson EN, Engelbach JA, Becker-Hapak M, Carayannopoulos LN, Piwnica-Worms D, Linette GP.

Clin Cancer Res. 2009 May 15;15(10):3277-86. doi: 10.1158/1078-0432.CCR-08-2502. Epub 2009 May 15.


CD40 regulates human dendritic cell-derived IL-7 production that, in turn, contributes to CD8(+) T-cell antigen-specific expansion.

Carreno BM, Becker-Hapak M, Linette GP.

Immunol Cell Biol. 2009 Feb;87(2):167-77. doi: 10.1038/icb.2008.80. Epub 2008 Nov 11.


The human IL-17F/IL-17A heterodimeric cytokine signals through the IL-17RA/IL-17RC receptor complex.

Wright JF, Bennett F, Li B, Brooks J, Luxenberg DP, Whitters MJ, Tomkinson KN, Fitz LJ, Wolfman NM, Collins M, Dunussi-Joannopoulos K, Chatterjee-Kishore M, Carreno BM.

J Immunol. 2008 Aug 15;181(4):2799-805.


Human major histocompatibility complex (MHC) class I molecules with disulfide traps secure disease-related antigenic peptides and exclude competitor peptides.

Truscott SM, Wang X, Lybarger L, Biddison WE, McBerry C, Martinko JM, Connolly JM, Linette GP, Fremont DH, Hansen TH, Carreno BM.

J Biol Chem. 2008 Mar 21;283(12):7480-90. doi: 10.1074/jbc.M709935200. Epub 2008 Jan 14.


Identification of an interleukin 17F/17A heterodimer in activated human CD4+ T cells.

Wright JF, Guo Y, Quazi A, Luxenberg DP, Bennett F, Ross JF, Qiu Y, Whitters MJ, Tomkinson KN, Dunussi-Joannopoulos K, Carreno BM, Collins M, Wolfman NM.

J Biol Chem. 2007 May 4;282(18):13447-55. Epub 2007 Mar 13.


PD-1/PD-L1, but not PD-1/PD-L2, interactions regulate the severity of experimental autoimmune encephalomyelitis.

Carter LL, Leach MW, Azoitei ML, Cui J, Pelker JW, Jussif J, Benoit S, Ireland G, Luxenberg D, Askew GR, Milarski KL, Groves C, Brown T, Carito BA, Percival K, Carreno BM, Collins M, Marusic S.

J Neuroimmunol. 2007 Jan;182(1-2):124-34. Epub 2006 Dec 19.


Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth-related oncogene-alpha and granulocyte colony-stimulating factor in bronchial epithelium: implications for airway inflammation in cystic fibrosis.

McAllister F, Henry A, Kreindler JL, Dubin PJ, Ulrich L, Steele C, Finder JD, Pilewski JM, Carreno BM, Goldman SJ, Pirhonen J, Kolls JK.

J Immunol. 2005 Jul 1;175(1):404-12.

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