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Items: 1 to 20 of 33


Stem cell cultures derived from pediatric brain tumors accurately model the originating tumors.

Wenger A, Larsson S, Danielsson A, Elbæk KJ, Kettunen P, Tisell M, Sabel M, Lannering B, Nordborg C, Schepke E, Carén H.

Oncotarget. 2017 Jan 26. doi: 10.18632/oncotarget.14826. [Epub ahead of print]


Preoperative systemic levels of VEGFA, IL-7, IL-17A, and TNF-β delineate two distinct groups of children with brain tumors.

Sandén E, Enríquez Pérez J, Visse E, Kool M, Carén H, Siesjö P, Darabi A.

Pediatr Blood Cancer. 2016 Dec;63(12):2112-2122. doi: 10.1002/pbc.26158.


MethPed: an R package for the identification of pediatric brain tumor subtypes.

Ahamed MT, Danielsson A, Nemes S, Carén H.

BMC Bioinformatics. 2016 Jul 2;17(1):262. doi: 10.1186/s12859-016-1144-0.


Differentiation therapy for glioblastoma - too many obstacles?

Carén H, Beck S, Pollard SM.

Mol Cell Oncol. 2015 Dec 28;3(2):e1124174. doi: 10.1080/23723556.2015.1124174.


Rapid and specific hypomethylation of enhancers in endothelial cells during adaptation to cell culturing.

Magnusson M, Larsson P, Lu EX, Bergh N, Carén H, Jern S.

Epigenetics. 2016 Aug 2;11(8):614-24. doi: 10.1080/15592294.2016.1192734.


Highly Synchronized Expression of Lineage-Specific Genes during In Vitro Hepatic Differentiation of Human Pluripotent Stem Cell Lines.

Ghosheh N, Olsson B, Edsbagge J, Küppers-Munther B, Van Giezen M, Asplund A, Andersson TB, Björquist P, Carén H, Simonsson S, Sartipy P, Synnergren J.

Stem Cells Int. 2016;2016:8648356. doi: 10.1155/2016/8648356.


Genome-wide methylation profiling identifies novel methylated genes in neuroblastoma tumors.

Olsson M, Beck S, Kogner P, Martinsson T, Carén H.

Epigenetics. 2016;11(1):74-84. doi: 10.1080/15592294.2016.1138195.


Alterations in Tumor DNA Are Related to Short Postoperative Survival in Patients Resected for Pancreatic Carcinoma Aimed at Cure.

Asting AG, Ljungman D, Carén H, Dambrauskas Z, Iresjö BM, Hyltander A, Naredi P, Lundholm K.

Pancreas. 2016 Jul;45(6):900-7. doi: 10.1097/MPA.0000000000000566.


Glioblastoma Stem Cells Respond to Differentiation Cues but Fail to Undergo Commitment and Terminal Cell-Cycle Arrest.

Carén H, Stricker SH, Bulstrode H, Gagrica S, Johnstone E, Bartlett TE, Feber A, Wilson G, Teschendorff AE, Bertone P, Beck S, Pollard SM.

Stem Cell Reports. 2015 Nov 10;5(5):829-42.


Dynamic Enhancer Methylation--A Previously Unrecognized Switch for Tissue-Type Plasminogen Activator Expression.

Magnusson M, Lu EX, Larsson P, Ulfhammer E, Bergh N, Carén H, Jern S.

PLoS One. 2015 Oct 28;10(10):e0141805. doi: 10.1371/journal.pone.0141805.


MethPed: a DNA methylation classifier tool for the identification of pediatric brain tumor subtypes.

Danielsson A, Nemes S, Tisell M, Lannering B, Nordborg C, Sabel M, Carén H.

Clin Epigenetics. 2015 Jul 9;7:62. doi: 10.1186/s13148-015-0103-3.


Aberrant immunostaining pattern of the CD24 glycoprotein in clinical samples and experimental models of pediatric medulloblastomas.

Sandén E, Dyberg C, Krona C, Visse E, Carén H, Northcott PA, Kool M, Ståhl N, Persson A, Englund E, Johnsen JI, Siesjö P, Darabi A.

J Neurooncol. 2015 May;123(1):1-13. doi: 10.1007/s11060-015-1758-5.


The dynamics of DNA methylation covariation patterns in carcinogenesis.

Teschendorff AE, Liu X, Caren H, Pollard SM, Beck S, Widschwendter M, Chen L.

PLoS Comput Biol. 2014 Jul 10;10(7):e1003709. doi: 10.1371/journal.pcbi.1003709.


Integrated virus-host methylome analysis in head and neck squamous cell carcinoma.

Wilson GA, Lechner M, Köferle A, Caren H, Butcher LM, Feber A, Fenton T, Jay A, Boshoff C, Beck S.

Epigenetics. 2013 Sep;8(9):953-61. doi: 10.4161/epi.25614.


Widespread resetting of DNA methylation in glioblastoma-initiating cells suppresses malignant cellular behavior in a lineage-dependent manner.

Stricker SH, Feber A, Engström PG, Carén H, Kurian KM, Takashima Y, Watts C, Way M, Dirks P, Bertone P, Smith A, Beck S, Pollard SM.

Genes Dev. 2013 Mar 15;27(6):654-69. doi: 10.1101/gad.212662.112.


The good, the bad and the ugly: epigenetic mechanisms in glioblastoma.

Carén H, Pollard SM, Beck S.

Mol Aspects Med. 2013 Jul-Aug;34(4):849-62. doi: 10.1016/j.mam.2012.06.007. Review.


The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastoma.

Djos A, Martinsson T, Kogner P, Carén H.

Mol Cancer. 2012 Jun 13;11:40. doi: 10.1186/1476-4598-11-40.


Comprehensive SNP array study of frequently used neuroblastoma cell lines; copy neutral loss of heterozygosity is common in the cell lines but uncommon in primary tumors.

Kryh H, Carén H, Erichsen J, Sjöberg RM, Abrahamsson J, Kogner P, Martinsson T.

BMC Genomics. 2011 Sep 7;12:443. doi: 10.1186/1471-2164-12-443.


COX-2 gene expression in colon cancer tissue related to regulating factors and promoter methylation status.

Asting AG, Carén H, Andersson M, Lönnroth C, Lagerstedt K, Lundholm K.

BMC Cancer. 2011 Jun 13;11:238. doi: 10.1186/1471-2407-11-238.


Identification of epigenetically regulated genes that predict patient outcome in neuroblastoma.

Carén H, Djos A, Nethander M, Sjöberg RM, Kogner P, Enström C, Nilsson S, Martinsson T.

BMC Cancer. 2011 Feb 11;11:66. doi: 10.1186/1471-2407-11-66.

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