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Items: 1 to 20 of 61

1.

Characterisation of the opposing effects of G6PD deficiency on cerebral malaria and severe malarial anaemia.

Clarke GM, Rockett K, Kivinen K, Hubbart C, Jeffreys AE, Rowlands K, Jallow M, Conway DJ, Bojang KA, Pinder M, Usen S, Sisay-Joof F, Sirugo G, Toure O, Thera MA, Konate S, Sissoko S, Niangaly A, Poudiougou B, Mangano VD, Bougouma EC, Sirima SB, Modiano D, Amenga-Etego LN, Ghansah A, Koram KA, Wilson MD, Enimil A, Evans J, Amodu OK, Olaniyan S, Apinjoh T, Mugri R, Ndi A, Ndila CM, Uyoga S, Macharia A, Peshu N, Williams TN, Manjurano A, Sepúlveda N, Clark TG, Riley E, Drakeley C, Reyburn H, Nyirongo V, Kachala D, Molyneux M, Dunstan SJ, Phu NH, Quyen NN, Thai CQ, Hien TT, Manning L, Laman M, Siba P, Karunajeewa H, Allen S, Allen A, Davis TM, Michon P, Mueller I, Molloy SF, Campino S, Kerasidou A, Cornelius VJ, Hart L, Shah SS, Band G, Spencer CC, Agbenyega T, Achidi E, Doumbo OK, Farrar J, Marsh K, Taylor T, Kwiatkowski DP; MalariaGEN Consortium..

Elife. 2017 Jan 9;6. pii: e15085. doi: 10.7554/eLife.15085.

2.

The variability and reproducibility of whole genome sequencing technology for detecting resistance to anti-tuberculous drugs.

Phelan J, O'Sullivan DM, Machado D, Ramos J, Whale AS, O'Grady J, Dheda K, Campino S, McNerney R, Viveiros M, Huggett JF, Clark TG.

Genome Med. 2016 Dec 22;8(1):132. doi: 10.1186/s13073-016-0385-x.

3.

Removing the bottleneck in whole genome sequencing of Mycobacterium tuberculosis for rapid drug resistance analysis: a call to action.

McNerney R, Clark TG, Campino S, Rodrigues C, Dolinger D, Smith L, Cabibbe AM, Dheda K, Schito M.

Int J Infect Dis. 2016 Dec 13. pii: S1201-9712(16)31642-3. doi: 10.1016/j.ijid.2016.11.422. [Epub ahead of print] Review.

4.

Characterizing the impact of sustained sulfadoxine/pyrimethamine use upon the Plasmodium falciparum population in Malawi.

Ravenhall M, Benavente ED, Mipando M, Jensen AT, Sutherland CJ, Roper C, Sepúlveda N, Kwiatkowski DP, Montgomery J, Phiri KS, Terlouw A, Craig A, Campino S, Ocholla H, Clark TG.

Malar J. 2016 Nov 29;15(1):575.

5.

Indels, structural variation, and recombination drive genomic diversity in Plasmodium falciparum.

Miles A, Iqbal Z, Vauterin P, Pearson R, Campino S, Theron M, Gould K, Mead D, Drury E, O'Brien J, Ruano Rubio V, MacInnis B, Mwangi J, Samarakoon U, Ranford-Cartwright L, Ferdig M, Hayton K, Su XZ, Wellems T, Rayner J, McVean G, Kwiatkowski D.

Genome Res. 2016 Sep;26(9):1288-99. doi: 10.1101/gr.203711.115.

6.

Genomic analysis of local variation and recent evolution in Plasmodium vivax.

Pearson RD, Amato R, Auburn S, Miotto O, Almagro-Garcia J, Amaratunga C, Suon S, Mao S, Noviyanti R, Trimarsanto H, Marfurt J, Anstey NM, William T, Boni MF, Dolecek C, Tran HT, White NJ, Michon P, Siba P, Tavul L, Harrison G, Barry A, Mueller I, Ferreira MU, Karunaweera N, Randrianarivelojosia M, Gao Q, Hubbart C, Hart L, Jeffery B, Drury E, Mead D, Kekre M, Campino S, Manske M, Cornelius VJ, MacInnis B, Rockett KA, Miles A, Rayner JC, Fairhurst RM, Nosten F, Price RN, Kwiatkowski DP.

Nat Genet. 2016 Aug;48(8):959-64. doi: 10.1038/ng.3599.

7.

Genomic variation in two gametocyte non-producing Plasmodium falciparum clonal lines.

Campino S, Benavente ED, Assefa S, Thompson E, Drought LG, Taylor CJ, Gorvett Z, Carret CK, Flueck C, Ivens AC, Kwiatkowski DP, Alano P, Baker DA, Clark TG.

Malar J. 2016 Apr 21;15:229. doi: 10.1186/s12936-016-1254-1.

8.

Mycobacterium tuberculosis whole genome sequencing and protein structure modelling provides insights into anti-tuberculosis drug resistance.

Phelan J, Coll F, McNerney R, Ascher DB, Pires DE, Furnham N, Coeck N, Hill-Cawthorne GA, Nair MB, Mallard K, Ramsay A, Campino S, Hibberd ML, Pain A, Rigouts L, Clark TG.

BMC Med. 2016 Mar 23;14:31. doi: 10.1186/s12916-016-0575-9.

9.

Recombination in pe/ppe genes contributes to genetic variation in Mycobacterium tuberculosis lineages.

Phelan JE, Coll F, Bergval I, Anthony RM, Warren R, Sampson SL, Gey van Pittius NC, Glynn JR, Crampin AC, Alves A, Bessa TB, Campino S, Dheda K, Grandjean L, Hasan R, Hasan Z, Miranda A, Moore D, Panaiotov S, Perdigao J, Portugal I, Sheen P, de Oliveira Sousa E, Streicher EM, van Helden PD, Viveiros M, Hibberd ML, Pain A, McNerney R, Clark TG.

BMC Genomics. 2016 Feb 29;17:151. doi: 10.1186/s12864-016-2467-y.

10.

Genetic determinants of anti-malarial acquired immunity in a large multi-centre study.

Shelton JM, Corran P, Risley P, Silva N, Hubbart C, Jeffreys A, Rowlands K, Craik R, Cornelius V, Hensmann M, Molloy S, Sepulveda N, Clark TG, Band G, Clarke GM, Spencer CC, Kerasidou A, Campino S, Auburn S, Tall A, Ly AB, Mercereau-Puijalon O, Sakuntabhai A, Djimdé A, Maiga B, Touré O, Doumbo OK, Dolo A, Troye-Blomberg M, Mangano VD, Verra F, Modiano D, Bougouma E, Sirima SB, Ibrahim M, Hussain A, Eid N, Elzein A, Mohammed H, Elhassan A, Elhassan I, Williams TN, Ndila C, Macharia A, Marsh K, Manjurano A, Reyburn H, Lemnge M, Ishengoma D, Carter R, Karunaweera N, Fernando D, Dewasurendra R, Drakeley CJ, Riley EM, Kwiatkowski DP, Rockett KA; MalariaGEN Consortium..

Malar J. 2015 Aug 28;14:333. doi: 10.1186/s12936-015-0833-x.

11.

PhyTB: Phylogenetic tree visualisation and sample positioning for M. tuberculosis.

Benavente ED, Coll F, Furnham N, McNerney R, Glynn JR, Campino S, Pain A, Mohareb FR, Clark TG.

BMC Bioinformatics. 2015 May 13;16:155. doi: 10.1186/s12859-015-0603-3.

12.

Genetic architecture of artemisinin-resistant Plasmodium falciparum.

Miotto O, Amato R, Ashley EA, MacInnis B, Almagro-Garcia J, Amaratunga C, Lim P, Mead D, Oyola SO, Dhorda M, Imwong M, Woodrow C, Manske M, Stalker J, Drury E, Campino S, Amenga-Etego L, Thanh TN, Tran HT, Ringwald P, Bethell D, Nosten F, Phyo AP, Pukrittayakamee S, Chotivanich K, Chuor CM, Nguon C, Suon S, Sreng S, Newton PN, Mayxay M, Khanthavong M, Hongvanthong B, Htut Y, Han KT, Kyaw MP, Faiz MA, Fanello CI, Onyamboko M, Mokuolu OA, Jacob CG, Takala-Harrison S, Plowe CV, Day NP, Dondorp AM, Spencer CC, McVean G, Fairhurst RM, White NJ, Kwiatkowski DP.

Nat Genet. 2015 Mar;47(3):226-34. doi: 10.1038/ng.3189.

13.

K13-propeller polymorphisms in Plasmodium falciparum parasites from sub-Saharan Africa.

Kamau E, Campino S, Amenga-Etego L, Drury E, Ishengoma D, Johnson K, Mumba D, Kekre M, Yavo W, Mead D, Bouyou-Akotet M, Apinjoh T, Golassa L, Randrianarivelojosia M, Andagalu B, Maiga-Ascofare O, Amambua-Ngwa A, Tindana P, Ghansah A, MacInnis B, Kwiatkowski D, Djimde AA.

J Infect Dis. 2015 Apr 15;211(8):1352-5. doi: 10.1093/infdis/jiu608. Erratum in: J Infect Dis. 2016 Jan 15;213(2):327.

14.

Optimized whole-genome amplification strategy for extremely AT-biased template.

Oyola SO, Manske M, Campino S, Claessens A, Hamilton WL, Kekre M, Drury E, Mead D, Gu Y, Miles A, MacInnis B, Newbold C, Berriman M, Kwiatkowski DP.

DNA Res. 2014 Dec;21(6):661-71. doi: 10.1093/dnares/dsu028.

15.

Glucose-6-phosphate dehydrogenase polymorphisms and susceptibility to mild malaria in Dogon and Fulani, Mali.

Maiga B, Dolo A, Campino S, Sepulveda N, Corran P, Rockett KA, Troye-Blomberg M, Doumbo OK, Clark TG.

Malar J. 2014 Jul 11;13:270. doi: 10.1186/1475-2875-13-270.

16.

Whole-genome scans provide evidence of adaptive evolution in Malawian Plasmodium falciparum isolates.

Ocholla H, Preston MD, Mipando M, Jensen AT, Campino S, MacInnis B, Alcock D, Terlouw A, Zongo I, Oudraogo JB, Djimde AA, Assefa S, Doumbo OK, Borrmann S, Nzila A, Marsh K, Fairhurst RM, Nosten F, Anderson TJ, Kwiatkowski DP, Craig A, Clark TG, Montgomery J.

J Infect Dis. 2014 Dec 15;210(12):1991-2000. doi: 10.1093/infdis/jiu349.

17.

A barcode of organellar genome polymorphisms identifies the geographic origin of Plasmodium falciparum strains.

Preston MD, Campino S, Assefa SA, Echeverry DF, Ocholla H, Amambua-Ngwa A, Stewart LB, Conway DJ, Borrmann S, Michon P, Zongo I, Ouédraogo JB, Djimde AA, Doumbo OK, Nosten F, Pain A, Bousema T, Drakeley CJ, Fairhurst RM, Sutherland CJ, Roper C, Clark TG.

Nat Commun. 2014 Jun 13;5:4052. doi: 10.1038/ncomms5052.

18.

A transcriptional switch underlies commitment to sexual development in malaria parasites.

Kafsack BF, Rovira-Graells N, Clark TG, Bancells C, Crowley VM, Campino SG, Williams AE, Drought LG, Kwiatkowski DP, Baker DA, Cortés A, Llinás M.

Nature. 2014 Mar 13;507(7491):248-52. doi: 10.1038/nature12920.

19.

estMOI: estimating multiplicity of infection using parasite deep sequencing data.

Assefa SA, Preston MD, Campino S, Ocholla H, Sutherland CJ, Clark TG.

Bioinformatics. 2014 May 1;30(9):1292-4. doi: 10.1093/bioinformatics/btu005.

20.

Genome-wide screen identifies new candidate genes associated with artemisinin susceptibility in Plasmodium falciparum in Kenya.

Borrmann S, Straimer J, Mwai L, Abdi A, Rippert A, Okombo J, Muriithi S, Sasi P, Kortok MM, Lowe B, Campino S, Assefa S, Auburn S, Manske M, Maslen G, Peshu N, Kwiatkowski DP, Marsh K, Nzila A, Clark TG.

Sci Rep. 2013 Nov 25;3:3318. doi: 10.1038/srep03318.

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