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Items: 1 to 20 of 249


Tissue distribution and clonal diversity of the T and B cell repertoire in type 1 diabetes.

Seay HR, Yusko E, Rothweiler SJ, Zhang L, Posgai AL, Campbell-Thompson M, Vignali M, Emerson RO, Kaddis JS, Ko D, Nakayama M, Smith MJ, Cambier JC, Pugliese A, Atkinson MA, Robins HS, Brusko TM.

JCI Insight. 2016 Dec 8;1(20):e88242.


B Cell Receptor Affinity for Insulin Dictates Autoantigen Acquisition and B Cell Functionality in Autoimmune Diabetes.

Packard TA, Smith MJ, Conrad FJ, Johnson SA, Getahun A, Lindsay RS, Hinman RM, Friedman RS, Thomas JW, Cambier JC.

J Clin Med. 2016 Nov 8;5(11). pii: E98.


Targeting B cells in treatment of autoimmunity.

Franks SE, Getahun A, Hogarth PM, Cambier JC.

Curr Opin Immunol. 2016 Dec;43:39-45. doi: 10.1016/j.coi.2016.09.003. Review.


Contamination of DNase Preparations Confounds Analysis of the Role of DNA in Alum-Adjuvanted Vaccines.

Noges LE, White J, Cambier JC, Kappler JW, Marrack P.

J Immunol. 2016 Aug 15;197(4):1221-30. doi: 10.4049/jimmunol.1501565.


Continuous inhibitory signaling by both SHP-1 and SHIP-1 pathways is required to maintain unresponsiveness of anergic B cells.

Getahun A, Beavers NA, Larson SR, Shlomchik MJ, Cambier JC.

J Exp Med. 2016 May 2;213(5):751-69. doi: 10.1084/jem.20150537.


γδ T Cells Shape Preimmune Peripheral B Cell Populations.

Huang Y, Getahun A, Heiser RA, Detanico TO, Aviszus K, Kirchenbaum GA, Casper TL, Huang C, Aydintug MK, Carding SR, Ikuta K, Huang H, Wysocki LJ, Cambier JC, O'Brien RL, Born WK.

J Immunol. 2016 Jan 1;196(1):217-31. doi: 10.4049/jimmunol.1501064.


Imbalanced PTEN and PI3K Signaling Impairs Class Switch Recombination.

Chen Z, Getahun A, Chen X, Dollin Y, Cambier JC, Wang JH.

J Immunol. 2015 Dec 1;195(11):5461-71. doi: 10.4049/jimmunol.1501375.


Of ITIMs, ITAMs, and ITAMis: revisiting immunoglobulin Fc receptor signaling.

Getahun A, Cambier JC.

Immunol Rev. 2015 Nov;268(1):66-73. doi: 10.1111/imr.12336. Review.


γδ T cells affect IL-4 production and B-cell tolerance.

Huang Y, Heiser RA, Detanico TO, Getahun A, Kirchenbaum GA, Casper TL, Aydintug MK, Carding SR, Ikuta K, Huang H, Cambier JC, Wysocki LJ, O'Brien RL, Born WK.

Proc Natl Acad Sci U S A. 2015 Jan 6;112(1):E39-48. doi: 10.1073/pnas.1415107111.


Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production.

White MJ, McArthur K, Metcalf D, Lane RM, Cambier JC, Herold MJ, van Delft MF, Bedoui S, Lessene G, Ritchie ME, Huang DC, Kile BT.

Cell. 2014 Dec 18;159(7):1549-62. doi: 10.1016/j.cell.2014.11.036.


Loss of anergic B cells in prediabetic and new-onset type 1 diabetic patients.

Smith MJ, Packard TA, O'Neill SK, Henry Dunand CJ, Huang M, Fitzgerald-Miller L, Stowell D, Hinman RM, Wilson PC, Gottlieb PA, Cambier JC.

Diabetes. 2015 May;64(5):1703-12. doi: 10.2337/db13-1798.


Role of B lymphocytes in the pathogenesis of type 1 diabetes.

Hinman RM, Cambier JC.

Curr Diab Rep. 2014;14(11):543. doi: 10.1007/s11892-014-0543-8. Review.


B cells and type 1 diabetes mice and men.

Hinman RM, Smith MJ, Cambier JC.

Immunol Lett. 2014 Aug;160(2):128-32. doi: 10.1016/j.imlet.2014.01.010. Review.


Anti-CD79 antibody induces B cell anergy that protects against autoimmunity.

Hardy IR, Anceriz N, Rousseau F, Seefeldt MB, Hatterer E, Irla M, Buatois V, Chatel LE, Getahun A, Fletcher A, Cons L, Pontini G, Hertzberg NA, Magistrelli G, Malinge P, Smith MJ, Reith W, Kosco-Vilbois MH, Ferlin WG, Cambier JC.

J Immunol. 2014 Feb 15;192(4):1641-50. doi: 10.4049/jimmunol.1302672.


B lymphocyte antigen receptor signaling: initiation, amplification, and regulation.

Packard TA, Cambier JC.

F1000Prime Rep. 2013 Oct 1;5:40. doi: 10.12703/P5-40. Review.


Cyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasome.

Abdul-Sater AA, Tattoli I, Jin L, Grajkowski A, Levi A, Koller BH, Allen IC, Beaucage SL, Fitzgerald KA, Ting JP, Cambier JC, Girardin SE, Schindler C.

EMBO Rep. 2013 Oct;14(10):900-6. doi: 10.1038/embor.2013.132.


Phosphatase regulation of immunoreceptor signaling in T cells, B cells and mast cells.

Bounab Y, Getahun A, Cambier JC, Daëron M.

Curr Opin Immunol. 2013 Jun;25(3):313-20. doi: 10.1016/j.coi.2013.04.001. Review.


Autoimmunity risk alleles: hotspots in B cell regulatory signaling pathways.

Cambier JC.

J Clin Invest. 2013 May;123(5):1928-31. doi: 10.1172/JCI69289.


STING/MPYS mediates host defense against Listeria monocytogenes infection by regulating Ly6C(hi) monocyte migration.

Jin L, Getahun A, Knowles HM, Mogan J, Akerlund LJ, Packard TA, Perraud AL, Cambier JC.

J Immunol. 2013 Mar 15;190(6):2835-43. doi: 10.4049/jimmunol.1201788.

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