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Items: 1 to 20 of 102


Genome-wide DNA methylation profiling in zebrafish.

Murphy PJ, Cairns BR.

Methods Cell Biol. 2016;135:345-59. doi: 10.1016/bs.mcb.2016.05.002.


Counteracting H3K4 methylation modulators Set1 and Jhd2 co-regulate chromatin dynamics and gene transcription.

Ramakrishnan S, Pokhrel S, Palani S, Pflueger C, Parnell TJ, Cairns BR, Bhaskara S, Chandrasekharan MB.

Nat Commun. 2016 Jun 21;7:11949. doi: 10.1038/ncomms11949.


Regulation of DNA Translocation Efficiency within the Chromatin Remodeler RSC/Sth1 Potentiates Nucleosome Sliding and Ejection.

Clapier CR, Kasten MM, Parnell TJ, Viswanathan R, Szerlong H, Sirinakis G, Zhang Y, Cairns BR.

Mol Cell. 2016 May 5;62(3):453-61. doi: 10.1016/j.molcel.2016.03.032.


Tet proteins enhance the developmental hourglass.

Hendrickson PG, Cairns BR.

Nat Genet. 2016 Apr;48(4):345-7. doi: 10.1038/ng.3533.


The impact of chromosomal translocation locus and fusion oncogene coding sequence in synovial sarcomagenesis.

Jones KB, Barrott JJ, Xie M, Haldar M, Jin H, Zhu JF, Monument MJ, Mosbruger TL, Langer EM, Randall RL, Wilson RK, Cairns BR, Ding L, Capecchi MR.

Oncogene. 2016 Sep 22;35(38):5021-32. doi: 10.1038/onc.2016.38.


Selective repression of SINE transcription by RNA polymerase III.

Varshney D, Vavrova-Anderson J, Oler AJ, Cairns BR, White RJ.

Mob Genet Elements. 2015 Sep 23;5(6):86-91.


Transcription and imprinting dynamics in developing postnatal male germline stem cells.

Hammoud SS, Low DH, Yi C, Lee CL, Oatley JM, Payne CJ, Carrell DT, Guccione E, Cairns BR.

Genes Dev. 2015 Nov 1;29(21):2312-24. doi: 10.1101/gad.261925.115.


Interaction of the Jhd2 Histone H3 Lys-4 Demethylase with Chromatin Is Controlled by Histone H2A Surfaces and Restricted by H2B Ubiquitination.

Huang F, Ramakrishnan S, Pokhrel S, Pflueger C, Parnell TJ, Kasten MM, Currie SL, Bhachech N, Horikoshi M, Graves BJ, Cairns BR, Bhaskara S, Chandrasekharan MB.

J Biol Chem. 2015 Nov 27;290(48):28760-77. doi: 10.1074/jbc.M115.693085.


Aberrant sperm DNA methylation predicts male fertility status and embryo quality.

Aston KI, Uren PJ, Jenkins TG, Horsager A, Cairns BR, Smith AD, Carrell DT.

Fertil Steril. 2015 Dec;104(6):1388-97.e1-5. doi: 10.1016/j.fertnstert.2015.08.019.


Experimental Approaches for Target Profiling of RNA Cytosine Methyltransferases.

Khoddami V, Yerra A, Cairns BR.

Methods Enzymol. 2015;560:273-96. doi: 10.1016/bs.mie.2015.03.008.


The chromatin remodelers RSC and ISW1 display functional and chromatin-based promoter antagonism.

Parnell TJ, Schlichter A, Wilson BG, Cairns BR.

Elife. 2015 Mar 30;4:e06073. doi: 10.7554/eLife.06073.


SINE transcription by RNA polymerase III is suppressed by histone methylation but not by DNA methylation.

Varshney D, Vavrova-Anderson J, Oler AJ, Cowling VH, Cairns BR, White RJ.

Nat Commun. 2015 Mar 23;6:6569. doi: 10.1038/ncomms7569.


HDAC1,2 inhibition impairs EZH2- and BBAP-mediated DNA repair to overcome chemoresistance in EZH2 gain-of-function mutant diffuse large B-cell lymphoma.

Johnson DP, Spitz GS, Tharkar S, Quayle SN, Shearstone JR, Jones S, McDowell ME, Wellman H, Tyler JK, Cairns BR, Chandrasekharan MB, Bhaskara S.

Oncotarget. 2015 Mar 10;6(7):4863-87.


Age-associated sperm DNA methylation alterations: possible implications in offspring disease susceptibility.

Jenkins TG, Aston KI, Pflueger C, Cairns BR, Carrell DT.

PLoS Genet. 2014 Jul 10;10(7):e1004458. doi: 10.1371/journal.pgen.1004458.


Chromatin and transcription transitions of mammalian adult germline stem cells and spermatogenesis.

Hammoud SS, Low DH, Yi C, Carrell DT, Guccione E, Cairns BR.

Cell Stem Cell. 2014 Aug 7;15(2):239-53. doi: 10.1016/j.stem.2014.04.006.


Transcriptome-wide target profiling of RNA cytosine methyltransferases using the mechanism-based enrichment procedure Aza-IP.

Khoddami V, Cairns BR.

Nat Protoc. 2014 Feb;9(2):337-61. doi: 10.1038/nprot.2014.014.


Probabilistic alignment leads to improved accuracy and read coverage for bisulfite sequencing data.

Hong C, Clement NL, Clement S, Hammoud SS, Carrell DT, Cairns BR, Snell Q, Clement MJ, Johnson WE.

BMC Bioinformatics. 2013 Nov 21;14:337. doi: 10.1186/1471-2105-14-337.


Reintroducing domesticated wild mice to sociality induces adaptive transgenerational effects on MUP expression.

Nelson AC, Cauceglia JW, Merkley SD, Youngson NA, Oler AJ, Nelson RJ, Cairns BR, Whitelaw E, Potts WK.

Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):19848-53. doi: 10.1073/pnas.1310427110.


Histone deacetylases 1 and 2 maintain S-phase chromatin and DNA replication fork progression.

Bhaskara S, Jacques V, Rusche JR, Olson EN, Cairns BR, Chandrasekharan MB.

Epigenetics Chromatin. 2013 Aug 15;6(1):27. doi: 10.1186/1756-8935-6-27.

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