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Items: 1 to 20 of 195


Structure-based discovery of clinically approved drugs as Zika virus NS2B-NS3 protease inhibitors that potently inhibit Zika virus infection in vitro and in vivo.

Yuan S, Chan JF, den-Haan H, Chik KK, Zhang AJ, Chan CC, Poon VK, Yip CC, Mak WW, Zhu Z, Zou Z, Tee KM, Cai JP, Chan KH, de la Peña J, Pérez-Sánchez H, Cerón-Carrasco JP, Yuen KY.

Antiviral Res. 2017 Jul 14;145:33-43. doi: 10.1016/j.antiviral.2017.07.007. [Epub ahead of print]


Levels of 8-oxo-dGsn and 8-oxo-Gsn in random urine are consistent with 24 h urine in healthy subjects and patients with renal disease.

Mao YH, Weng QH, Xu LN, Li XY, Zhao B, Sun Y, Nie JJ, Hu JH, Zhou Q, Zhang LQ, Guo J, Zuo MZ, Ito S, Cai JP.

Free Radic Res. 2017 Jul 10:1-6. doi: 10.1080/10715762.2017.1346249. [Epub ahead of print]


Effects of CYP2C19 Variants on Fluoxetine Metabolism in vitro.

Fang P, He JY, Han AX, Lan T, Dai DP, Cai JP, Hu GX.

Pharmacology. 2017;100(1-2):91-97. doi: 10.1159/000475598. Epub 2017 May 12.


Selective Activation of Type II Interferon Signaling by Zika Virus NS5 Protein.

Chaudhary V, Yuen KS, Chan JF, Chan CP, Wang PH, Cai JP, Zhang S, Liang M, Kok KH, Chan CP, Yuen KY, Jin DY.

J Virol. 2017 Jun 26;91(14). pii: e00163-17. doi: 10.1128/JVI.00163-17. Print 2017 Jul 15.


Systematic screening for CYP3A4 genetic polymorphisms in a Han Chinese population.

Hu GX, Dai DP, Wang H, Huang XX, Zhou XY, Cai J, Chen H, Cai JP.

Pharmacogenomics. 2017 Mar;18(4):369-379. doi: 10.2217/pgs-2016-0179. Epub 2017 Feb 17.


Adipose-specific deletion of Kif5b exacerbates obesity and insulin resistance in a mouse model of diet-induced obesity.

Cui J, Pang J, Lin YJ, Gong H, Wang ZH, Li YX, Li J, Wang Z, Jiang P, Dai DP, Li J, Cai JP, Huang JD, Zhang TM.

FASEB J. 2017 Jun;31(6):2533-2547. doi: 10.1096/fj.201601103R. Epub 2017 Feb 27.


Identification of the novel HLA-DRB1*14:54:06 allele by sequencing-based typing in a Chinese bone marrow donor.

Zhou XY, Jiang P, Zhang LQ, Cai JP.

HLA. 2017 Mar;89(3):172-173. doi: 10.1111/tan.12962. Epub 2017 Jan 22.


Talaromyces marneffei Mp1p Is a Virulence Factor that Binds and Sequesters a Key Proinflammatory Lipid to Dampen Host Innate Immune Response.

Sze KH, Lam WH, Zhang H, Ke YH, Tse MK, Woo PC, Lau SK, Lau CC, Cai JP, Tung ET, Lo RK, Xu S, Kao RY, Hao Q, Yuen KY.

Cell Chem Biol. 2017 Feb 16;24(2):182-194. doi: 10.1016/j.chembiol.2016.12.014. Epub 2017 Jan 19.


A new HLA-B*55 allele, B*55:83N with a stop codon in exon 4 generated by a point mutation, identified in a Chinese individual.

Zhou XY, Jiang P, Zhang LQ, Cui J, Cai JP.

HLA. 2017 Feb;89(2):119-120. doi: 10.1111/tan.12953.


Effect of 22 CYP2D6 variants found in the Chinese population on tolterodine metabolism in vitro.

Wang H, Dai DP, Sun P, Xu LP, Liang BQ, Cai JP, Hu GX.

Chem Biol Interact. 2017 Feb 25;264:10-15. doi: 10.1016/j.cbi.2017.01.003. Epub 2017 Jan 10.


Identification and interspecies transmission of a novel bocaparvovirus among different bat species in China.

Lau SK, Ahmed SS, Yeung HC, Li KS, Fan RY, Cheng TY, Cai JP, Wang M, Zheng BJ, Wong SS, Woo PC, Yuen KY.

J Gen Virol. 2016 Dec;97(12):3345-3358. doi: 10.1099/jgv.0.000645. Epub 2016 Oct 25.


Zika Virus Infection in Dexamethasone-immunosuppressed Mice Demonstrating Disseminated Infection with Multi-organ Involvement Including Orchitis Effectively Treated by Recombinant Type I Interferons.

Chan JF, Zhang AJ, Chan CC, Yip CC, Mak WW, Zhu H, Poon VK, Tee KM, Zhu Z, Cai JP, Tsang JO, Chik KK, Yin F, Chan KH, Kok KH, Jin DY, Au-Yeung RK, Yuen KY.

EBioMedicine. 2016 Dec;14:112-122. doi: 10.1016/j.ebiom.2016.11.017. Epub 2016 Nov 12.


Identification and genomic characterization of a novel rat bocavirus from brown rats in China.

Lau SK, Yeung HC, Li KS, Lam CS, Cai JP, Yuen MC, Wang M, Zheng BJ, Woo PC, Yuen KY.

Infect Genet Evol. 2017 Jan;47:68-76. doi: 10.1016/j.meegid.2016.11.014. Epub 2016 Nov 19.


Persistence of antibodies acquired by natural hepatitis E virus infection and effects of vaccination.

Su YY, Huang SJ, Guo M, Zhao J, Yu H, He WG, Jiang HM, Wang YJ, Zhang XF, Cai JP, Yang CL, Wang ZZ, Zhu FC, Wu T, Zhang J, Xia NS.

Clin Microbiol Infect. 2017 May;23(5):336.e1-336.e4. doi: 10.1016/j.cmi.2016.10.029. Epub 2016 Nov 9.


Identifying Novel B Cell Epitopes within Toxoplasma gondii GRA6.

Wang Y, Wang G, Cai JP.

Korean J Parasitol. 2016 Aug;54(4):431-7. doi: 10.3347/kjp.2016.54.4.431. Epub 2016 Aug 31.


A rapid and sensitive UHPLC-MS/MS assay for the determination of trelagliptin in rat plasma and its application to a pharmacokinetic study.

Hu XX, Lan T, Chen Z, Yang CC, Tang PF, Yuan LJ, Hu GX, Cai JP.

J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Oct 15;1033-1034:166-71. doi: 10.1016/j.jchromb.2016.08.024. Epub 2016 Aug 16.


Mp1p Is a Virulence Factor in Talaromyces (Penicillium) marneffei.

Woo PC, Lau SK, Lau CC, Tung ET, Chong KT, Yang F, Zhang H, Lo RK, Cai JP, Au-Yeung RK, Ng WF, Tse H, Wong SS, Xu S, Lam WH, Tse MK, Sze KH, Kao RY, Reiner NE, Hao Q, Yuen KY.

PLoS Negl Trop Dis. 2016 Aug 25;10(8):e0004907. doi: 10.1371/journal.pntd.0004907. eCollection 2016 Aug.


Differential cell line susceptibility to the emerging Zika virus: implications for disease pathogenesis, non-vector-borne human transmission and animal reservoirs.

Chan JF, Yip CC, Tsang JO, Tee KM, Cai JP, Chik KK, Zhu Z, Chan CC, Choi GK, Sridhar S, Zhang AJ, Lu G, Chiu K, Lo AC, Tsao SW, Kok KH, Jin DY, Chan KH, Yuen KY.

Emerg Microbes Infect. 2016 Aug 24;5:e93. doi: 10.1038/emi.2016.99.


EYA4 gene functions as a prognostic marker and inhibits the growth of intrahepatic cholangiocarcinoma.

Hao XY, Cai JP, Liu X, Chen W, Hou X, Chen D, Lai JM, Liang LJ, Yin XY.

Chin J Cancer. 2016 Jul 28;35(1):70. doi: 10.1186/s40880-016-0133-z.

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