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Items: 1 to 20 of 53

1.

Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology.

Horsburgh K, Wardlaw JM, van Agtmael T, Allan SM, Ashford MLJ, Bath PM, Brown R, Berwick J, Cader MZ, Carare RO, Davis JB, Duncombe J, Farr TD, Fowler JH, Goense J, Granata A, Hall CN, Hainsworth AH, Harvey A, Hawkes CA, Joutel A, Kalaria RN, Kehoe PG, Lawrence CB, Lockhart A, Love S, Macleod MR, Macrae IM, Markus HS, McCabe C, McColl BW, Meakin PJ, Miller A, Nedergaard M, O'Sullivan M, Quinn TJ, Rajani R, Saksida LM, Smith C, Smith KJ, Touyz RM, Trueman RC, Wang T, Williams A, Williams SCR, Work LM.

Clin Sci (Lond). 2018 Apr 30;132(8):851-868. doi: 10.1042/CS20171620. Print 2018 Apr 30. Review.

PMID:
29712883
2.

Neurovascular dysfunction in dementia - human cellular models and molecular mechanisms.

Parkes I, Chintawar S, Cader MZ.

Clin Sci (Lond). 2018 Feb 14;132(3):399-418. doi: 10.1042/CS20160720. Print 2018 Feb 14. Review.

PMID:
29444850
3.

HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease.

Benoy V, Van Helleputte L, Prior R, d'Ydewalle C, Haeck W, Geens N, Scheveneels W, Schevenels B, Cader MZ, Talbot K, Kozikowski AP, Vanden Berghe P, Van Damme P, Robberecht W, Van Den Bosch L.

Brain. 2018 Mar 1;141(3):673-687. doi: 10.1093/brain/awx375.

4.

Aligned electrospun fibers for neural patterning.

Soliman E, Bianchi F, Sleigh JN, George JH, Cader MZ, Cui Z, Ye H.

Biotechnol Lett. 2018 Mar;40(3):601-607. doi: 10.1007/s10529-017-2494-z. Epub 2018 Jan 8.

5.

Engineered method for directional growth of muscle sheets on electrospun fibers.

Soliman E, Bianchi F, Sleigh JN, George JH, Cader MZ, Cui Z, Ye H.

J Biomed Mater Res A. 2018 May;106(5):1165-1176. doi: 10.1002/jbm.a.36312. Epub 2018 Jan 9.

PMID:
29266766
6.

A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response.

Haenseler W, Sansom SN, Buchrieser J, Newey SE, Moore CS, Nicholls FJ, Chintawar S, Schnell C, Antel JP, Allen ND, Cader MZ, Wade-Martins R, James WS, Cowley SA.

Stem Cell Reports. 2017 Jun 6;8(6):1727-1742. doi: 10.1016/j.stemcr.2017.05.017.

7.

Trk receptor signaling and sensory neuron fate are perturbed in human neuropathy caused by Gars mutations.

Sleigh JN, Dawes JM, West SJ, Wei N, Spaulding EL, Gómez-Martín A, Zhang Q, Burgess RW, Cader MZ, Talbot K, Yang XL, Bennett DL, Schiavo G.

Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):E3324-E3333. doi: 10.1073/pnas.1614557114. Epub 2017 Mar 28.

8.

Multiplex High-Throughput Targeted Proteomic Assay To Identify Induced Pluripotent Stem Cells.

Baud A, Wessely F, Mazzacuva F, McCormick J, Camuzeaux S, Heywood WE, Little D, Vowles J, Tuefferd M, Mosaku O, Lako M, Armstrong L, Webber C, Cader MZ, Peeters P, Gissen P, Cowley SA, Mills K.

Anal Chem. 2017 Feb 21;89(4):2440-2448. doi: 10.1021/acs.analchem.6b04368. Epub 2017 Feb 6.

PMID:
28192931
9.

Mitophagy and Alzheimer's Disease: Cellular and Molecular Mechanisms.

Kerr JS, Adriaanse BA, Greig NH, Mattson MP, Cader MZ, Bohr VA, Fang EF.

Trends Neurosci. 2017 Mar;40(3):151-166. doi: 10.1016/j.tins.2017.01.002. Epub 2017 Feb 9. Review.

10.

C13orf31 (FAMIN) is a central regulator of immunometabolic function.

Cader MZ, Boroviak K, Zhang Q, Assadi G, Kempster SL, Sewell GW, Saveljeva S, Ashcroft JW, Clare S, Mukhopadhyay S, Brown KP, Tschurtschenthaler M, Raine T, Doe B, Chilvers ER, Griffin JL, Kaneider NC, Floto RA, D'Amato M, Bradley A, Wakelam MJ, Dougan G, Kaser A.

Nat Immunol. 2016 Sep;17(9):1046-56. doi: 10.1038/ni.3532. Epub 2016 Aug 1.

PMID:
27478939
11.

Reprogramming psychiatry: stem cells and bipolar disorder.

Harrison PJ, Cader MZ, Geddes JR.

Lancet. 2016 Feb 27;387(10021):823-5. doi: 10.1016/S0140-6736(16)00235-X. Epub 2016 Feb 26. No abstract available.

PMID:
26972063
12.

Assessing similarity to primary tissue and cortical layer identity in induced pluripotent stem cell-derived cortical neurons through single-cell transcriptomics.

Handel AE, Chintawar S, Lalic T, Whiteley E, Vowles J, Giustacchini A, Argoud K, Sopp P, Nakanishi M, Bowden R, Cowley S, Newey S, Akerman C, Ponting CP, Cader MZ.

Hum Mol Genet. 2016 Mar 1;25(5):989-1000. doi: 10.1093/hmg/ddv637. Epub 2016 Jan 5.

13.

StemBANCC: Governing Access to Material and Data in a Large Stem Cell Research Consortium.

Morrison M, Klein C, Clemann N, Collier DA, Hardy J, Heisserer B, Cader MZ, Graf M, Kaye J.

Stem Cell Rev. 2015 Oct;11(5):681-7. doi: 10.1007/s12015-015-9599-3. Review.

14.

Dominant, toxic gain-of-function mutations in gars lead to non-cell autonomous neuropathology.

Grice SJ, Sleigh JN, Motley WW, Liu JL, Burgess RW, Talbot K, Cader MZ.

Hum Mol Genet. 2015 Aug 1;24(15):4397-406. doi: 10.1093/hmg/ddv176. Epub 2015 May 13.

15.

EBNA2 binds to genomic intervals associated with multiple sclerosis and overlaps with vitamin D receptor occupancy.

Ricigliano VA, Handel AE, Sandve GK, Annibali V, Ristori G, Mechelli R, Cader MZ, Salvetti M.

PLoS One. 2015 Apr 8;10(4):e0119605. doi: 10.1371/journal.pone.0119605. eCollection 2015.

16.

Altered neurochemical coupling in the occipital cortex in migraine with visual aura.

Bridge H, Stagg CJ, Near J, Lau CI, Zisner A, Cader MZ.

Cephalalgia. 2015 Oct;35(11):1025-30. doi: 10.1177/0333102414566860. Epub 2015 Jan 28.

PMID:
25631169
17.

Diagnostic outcomes associated with ankle synovitis in early inflammatory arthritis: a cohort study.

Abhishek A, de Pablo P, Cader MZ, Buckley CD, Raza K, Filer A.

Clin Exp Rheumatol. 2014 Jul-Aug;32(4):533-8. Epub 2014 Jul 1.

PMID:
24983292
18.

Morphological analysis of neuromuscular junction development and degeneration in rodent lumbrical muscles.

Sleigh JN, Burgess RW, Gillingwater TH, Cader MZ.

J Neurosci Methods. 2014 Apr 30;227:159-65. doi: 10.1016/j.jneumeth.2014.02.005. Epub 2014 Feb 14.

19.

Cloxyquin (5-chloroquinolin-8-ol) is an activator of the two-pore domain potassium channel TRESK.

Wright PD, Weir G, Cartland J, Tickle D, Kettleborough C, Cader MZ, Jerman J.

Biochem Biophys Res Commun. 2013 Nov 15;441(2):463-8.

PMID:
24383077
20.

Neuromuscular junction maturation defects precede impaired lower motor neuron connectivity in Charcot-Marie-Tooth type 2D mice.

Sleigh JN, Grice SJ, Burgess RW, Talbot K, Cader MZ.

Hum Mol Genet. 2014 May 15;23(10):2639-50. doi: 10.1093/hmg/ddt659. Epub 2013 Dec 23.

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